Zobrazeno 1 - 10
of 391
pro vyhledávání: '"Weiping Zou"'
Autor:
Jae Eun Choi, Yuanyuan Qiao, Ilona Kryczek, Jiali Yu, Jonathan Gurkan, Yi Bao, Mahnoor Gondal, Jean Ching-Yi Tien, Tomasz Maj, Sahr Yazdani, Abhijit Parolia, Houjun Xia, JiaJia Zhou, Shuang Wei, Sara Grove, Linda Vatan, Heng Lin, Gaopeng Li, Yang Zheng, Yuping Zhang, Xuhong Cao, Fengyun Su, Rui Wang, Tongchen He, Marcin Cieslik, Michael D. Green, Weiping Zou, Arul M. Chinnaiyan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cancer treatment continues to shift from utilizing traditional therapies to targeted ones, such as protein kinase inhibitors and immunotherapy. Mobilizing dendritic cells (DC) and other myeloid cells with antigen presenting and cancer cell k
Externí odkaz:
https://doaj.org/article/110a46dd843f458b99af5d4a3c335b08
Autor:
Yousef Zakharia, Eric A. Singer, Satwik Acharyya, Rohan Garje, Monika Joshi, David Peace, Veera Baladandayuthapani, Annesha Majumdar, Xiong Li, Claudia Lalancette, Ilona Kryczek, Weiping Zou, Ajjai Alva
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Epigenetic modulation is well established in hematologic malignancies but to a lesser degree in solid tumors. Here we report the results of a phase Ib/II study of guadecitabine and durvalumab in advanced clear cell renal cell carcinoma (ccRC
Externí odkaz:
https://doaj.org/article/b61aeb1f55d4407694b815cd85d405bf
Autor:
Alex K. Bryant, Rafael Zamora‐Resendiz, Xin Dai, Destinee Morrow, Yuewei Lin, Kassidy M. Jungles, James M. Rae, Akshay Tate, Ashley N. Pearson, Ralph Jiang, Lars Fritsche, Theodore S. Lawrence, Weiping Zou, Matthew Schipper, Nithya Ramnath, Shinjae Yoo, Silvia Crivelli, Michael D. Green
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Purpose Real world evidence is crucial to understanding the diffusion of new oncologic therapies, monitoring cancer outcomes, and detecting unexpected toxicities. In practice, real world evidence is challenging to collect rapidly and compreh
Externí odkaz:
https://doaj.org/article/24564ba419ab4b8aac5c0b927356a621
Autor:
Fabiana Gregucci, Sheila Spada, Mary Helen Barcellos-Hoff, Nina Bhardwaj, Charleen Chan Wah Hak, Alba Fiorentino, Chandan Guha, Monica L. Guzman, Kevin Harrington, Fernanda G. Herrera, Jamie Honeychurch, Theodore Hong, Lorea Iturri, Elisabeth Jaffee, Sana D. Karam, Simon R.V. Knott, Constantinos Koumenis, David Lyden, Ariel E. Marciscano, Alan Melcher, Michele Mondini, Anna Mondino, Zachary S. Morris, Sean Pitroda, Sergio A. Quezada, Laura Santambrogio, Stephen Shiao, John Stagg, Irma Telarovic, Robert Timmerman, Marie-Catherine Vozenin, Ralph Weichselbaum, James Welsh, Anna Wilkins, Chris Xu, Roberta Zappasodi, Weiping Zou, Alexandre Bobard, Sandra Demaria, Lorenzo Galluzzi, Eric Deutsch, Silvia C. Formenti
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTFocal radiation therapy (RT) has attracted considerable attention as a combinatorial partner for immunotherapy (IT), largely reflecting a well-defined, predictable safety profile and at least some potential for immunostimulation. However, onl
Externí odkaz:
https://doaj.org/article/420f3d04260044b482062ca48125b481
Autor:
Michael B. Mumphrey, Noshad Hosseini, Abhijit Parolia, Jie Geng, Weiping Zou, Malini Raghavan, Arul Chinnaiyan, Marcin Cieslik
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112965- (2023)
Summary: Disruption of antigen presentation via loss of major histocompatibility complex (MHC) expression is a strategy whereby cancer cells escape immune surveillance and develop resistance to immunotherapy. Here, we develop the personalized genomic
Externí odkaz:
https://doaj.org/article/d0c6d870f1f846c894747d75024f6dd8
Autor:
Danfeng Sun, Weichao Wang, Fangfang Guo, Michael R. Pitter, Wan Du, Shuang Wei, Sara Grove, Linda Vatan, Yingxuan Chen, Ilona Kryczek, Eric R. Fearon, Jing-Yuan Fang, Weiping Zou
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Chronic inflammation and oncogenic pathway activation are key-contributing factors in colorectal cancer pathogenesis. However, colorectal intrinsic mechanisms linking these two factors in cancer development are poorly defined. Here, we show that inte
Externí odkaz:
https://doaj.org/article/b15ed1fa7f02475197f41ee424609607
Autor:
Shasha Li, Jiali Yu, Amanda Huber, Ilona Kryczek, Zhuwen Wang, Long Jiang, Xiong Li, Wan Du, Gaopeng Li, Shuang Wei, Linda Vatan, Wojciech Szeliga, Arul M. Chinnaiyan, Michael D. Green, Marcin Cieslik, Weiping Zou
Publikováno v:
Cell Reports, Vol 39, Iss 1, Pp 110609- (2022)
Summary: Tumor-associated macrophages (TAMs) are a major cellular component in the tumor microenvironment (TME). However, the relationship between the phenotype and metabolic pattern of TAMs remains poorly understood. We performed single-cell transcr
Externí odkaz:
https://doaj.org/article/cf19bac1b0044715a74b077d445979ea
Autor:
Erin A. Holcomb, Weiping Zou
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 3 (2022)
IL-2 is a pleiotropic cytokine. In this issue of the JCI, Ren et al. report on the development of a low-affinity IL-2 paired with anti–PD-1 (PD-1–laIL-2) that reactivates intratumoral CD8+ T cells, but not CD4+ Treg cells. PD-1–laIL-2 treatment
Externí odkaz:
https://doaj.org/article/3a9e27c86b844a7ba113b8f7f112a808
Autor:
Jiayin Tang, Tingting Yan, Yujie Bao, Chaoqin Shen, Chenyang Yu, Xiaoqiang Zhu, Xianglong Tian, Fangfang Guo, Qian Liang, Qiang Liu, Ming Zhong, Jinxian Chen, Zhizheng Ge, Xiaobo Li, Xiaoyu Chen, Yun Cui, Yingxuan Chen, Weiping Zou, Haoyan Chen, Jie Hong, Jing-Yuan Fang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
lncRNA and cellular metabolism are frequently dysregulated in cancer. In this study, the authors discover the lncGLCC1 is increased in colorectal cancer cells under glucose starvation conditions and correlates with poor prognosis in this cancer.
Externí odkaz:
https://doaj.org/article/3bdfa59d5ab74709ab6814e3fa0fb544
Autor:
Michael Green, Dmitriy Zamarin, Katherine Panageas, Taha Merghoub, Weiping Zou, Cailian Liu, Jedd Wolchok, Matthew Hellmann, Joseph Chan, Hongyu Shi, Hira Rizvi, Jessica Waninger, Aditi Gupta, Nicholas Ceglia, Viola Allaj, Giulia Zago, Nisarg Shah, Sai Sharma, Marissa Mattar, Yonina Bykov, Corrin Wohlhieter, Fathema Uddin, Inna Khodos, Angel Qin, Vinod Balachandran, Sohrab Shah, Andrew McPherson, Jason Lewis, Justin Perry, Elisa de Stanchina, Triparna Sen, John Poirier, Charles Rudin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/40d967b30569450689026463a728aa99