Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Weiping J. Zhang"'
Autor:
Mingming Xing, Yang Li, Yuqi Zhang, Juemou Zhou, Danting Ma, Mengqi Zhang, Minglei Tang, Ting Ouyang, Fumiao Zhang, Xiaofeng Shi, Jianyuan Sun, Zuxin Chen, Weiping J. Zhang, Shuli Zhang, Xiangyang Xie
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract The paraventricular hypothalamus (PVH) is crucial for food intake control, yet the presynaptic mechanisms underlying PVH neurons remain unclear. Here, we show that RUVBL2 in the PVH is significantly reduced during energy deficit, and knockou
Externí odkaz:
https://doaj.org/article/e355cb264c7f44cd8593ee4bc233abfe
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33278- (2024)
Arginase, an enzyme dependent on manganese (Mn), plays a crucial role in the production of urea and processing of ammonia in the liver. Previous studies have shown that overconsumption of fructose disrupts Mn homeostasis in the liver of male mice. Ho
Externí odkaz:
https://doaj.org/article/70c84fbbe1a549de8bad129ddb47ba1d
Autor:
Jian-Hui Shi, Yu-Xia Chen, Yingying Feng, Xiaohang Yang, Jie Lin, Ting Wang, Chun-Chun Wei, Xian-Hua Ma, Rui Yang, Dongmei Cao, Hai Zhang, Xiangyang Xie, Zhifang Xie, Weiping J. Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Arginase, a manganese (Mn)-dependent enzyme, is indispensable for urea generation and ammonia disposal in the liver. The potential role of fructose in Mn and ammonia metabolism is undefined. Here we demonstrate that fructose overconsumption
Externí odkaz:
https://doaj.org/article/014ff36b029a4ce38946bd821c2f6fce
Autor:
Jian Xiao, Le-Wei Dong, Shuai Liu, Fan-Hua Meng, Chang Xie, Xiao-Yi Lu, Weiping J. Zhang, Jie Luo, Bao-Liang Song
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Niemann-Pick C1-like 1 (NPC1L1) is essential for intestinal cholesterol absorption. Together with the cholesterol-rich and Flotillin-positive membrane microdomain, NPC1L1 is internalized via clathrin-mediated endocytosis and transported to e
Externí odkaz:
https://doaj.org/article/f8e1015e759a442db518284ebdf1b709
Publikováno v:
Chinese Medical Journal, Vol 134, Iss 11, Pp 1276-1285 (2021)
Abstract. Excessive consumption of fructose, the sweetest of all naturally occurring carbohydrates, has been linked to worldwide epidemics of metabolic diseases in humans, and it is considered an independent risk factor for cardiovascular diseases. W
Externí odkaz:
https://doaj.org/article/0386503c20af4d56889b1421852968a3
Autor:
Zhenbang Qin, Ping Wang, Weiwen Chen, Jue-Rui Wang, Xianhua Ma, Hai Zhang, Weiping J. Zhang, Chunchun Wei
Publikováno v:
Biochemical and Biophysical Research Communications. 658:128-135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e465cec927210a7f29d4b8be140ca951
https://doi.org/10.1016/j.bbrc.2023.03.075
https://doi.org/10.1016/j.bbrc.2023.03.075
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Recent studies have shown that ZBTB20, a zinc-finger protein containing transcription factor, is highly expressed in small-diameter primary sensory neurons in mice, and modulates pain through regulating TRP channels. However, whether ZBTB20 regulates
Externí odkaz:
https://doaj.org/article/12f23b0701c641e8ad6df83ebc55f740
Autor:
Yiruo Ma, Siyi Shen, Ying Yan, Shengjie Zhang, Shengnan Liu, Zhili Tang, Jing Yu, Mei Ma, Zhoumin Niu, Zhuoyang Li, Yuting Wu, Lin Zhao, Zhiqiang Lu, Chunchun Wei, Weiping J. Zhang, Ying Xue, Qiwei Zhai, Yu Li, Cheng Hu, Jingjing Jiang, Yuying Li, Hao Ying
Publikováno v:
Diabetes. 72:562-574
Thyroid hormone (TH) has a profound effect on energy metabolism and systemic homeostasis. Adipose tissues are crucial for maintaining whole-body homeostasis; however, whether TH regulates systemic metabolic homeostasis through its action on adipose t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86a23bbabe6bc038d05a82000738df5e
https://doi.org/10.2337/db22-0656
https://doi.org/10.2337/db22-0656
Autor:
Gan Liu, Luting Zhou, Hai Zhang, Rong Chen, Ye Zhang, Ling Li, Jun-Yu Lu, Hui Jiang, Dong Liu, Shasha Qi, Ying-Ming Jiang, Kai Yin, Zhifang Xie, Yuguang Shi, Yong Liu, Xuetao Cao, Yu-Xia Chen, Dajin Zou, Weiping J. Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
De novo lipogenesis is tightly controlled by hormonal and nutritional signals and plays an important role in energy homoeostasis. Here, Liu et al. show that zinc finger protein ZBTB20 regulates the expression of key glycolytic and lipogenic genes by
Externí odkaz:
https://doaj.org/article/b81cc4076fdc4b64ab9d4bbb68641880
Autor:
Qiufang Bai, Yajin Liu, Chen-Ma Wang, Jue-Rui Wang, Yingying Feng, Xianhua Ma, Xiaohang Yang, Ya-Nan Shi, Weiping J Zhang
Publikováno v:
Endocrinology. 164
Fructose intolerance in mammals is caused by defects in fructose absorption and metabolism. Fructose-1,6-bisphosphatase 1 (FBP1) is a key enzyme in gluconeogenesis, and its deficiency results in hypoglycemia as well as intolerance to fructose. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::678f5e81bbb66fb3765cd530537cb0d3
https://doi.org/10.1210/endocr/bqad054
https://doi.org/10.1210/endocr/bqad054