Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Weipert, J"'
Autor:
Jacek Kohl, Claudia Keser, Michael Spannagl, W. Machleidt, Leonhard Schweiberer, Matthias Siebeck, Weipert J
Publikováno v:
Europe PubMed Central
We wanted to determine the effects of WEB 2086, a platelet activating factor (PAF) antagonist, in lipopolysaccharide (LPS) shock in anesthetized pigs. In a randomized study, LPS from S. abortus equi, 2 micrograms/kg/h was given IV for six hours. Thir
Autor:
Michael Spannagl, Matthias Siebeck, Hans Fritz, Marianne Jochum, Leonhard Schweiberer, Weipert J, Peter Kroworsch, Kazuaki Shimamoto, Edwin Fink
Publikováno v:
Europe PubMed Central
Activation of the contact phase of coagulation has been implicated in the pathogenesis of septic shock. We wanted to determine if inhibition of plasma kallikrein can prevent arterial hypotension and liberation of kinins from kininogen, induced by an
Autor:
Hans Hoffmann, Hans Peter Schwarz, Michael Spannagl, Wolfgang Schramm, Matthias Siebeck, Weipert J
Publikováno v:
Thrombosis research. 61(1)
Inhibition of activated clotting factors is an important therapeutic approach in disseminated intravascular coagulation (DIC). We examined the possible protective effect of a purified complex of human antithrombin III (AT III) and heparin in endotoxi
Akademický článek
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Publikováno v:
Research in Experimental Medicine; 1988, Vol. 188 Issue 3, p183-187, 5p
Publikováno v:
Klinische Wochenschrift; Sep1985, Vol. 63 Issue 18, p948-958, 11p
Publikováno v:
European Journal of Cardio-Thoracic Surgery; October 1997, Vol. 12 Issue: 4 p574-580, 7p
Publikováno v:
Europe PubMed Central
The selective competitive bradykinin (BK) antagonist (B4148) produced significant inhibition of the hypotensive effect of BK in rats. Using a rat model of endotoxin shock, the fall in mean arterial blood pressure to an intravenous injection of lipopo
Publikováno v:
Europe PubMed Central
Thrombin activation is an important underlying pathomechanism for septic organ failure. The selective thrombin inhibitor, hirudin, reduces the endotoxin-induced fibrinogen consumption and thus the formation of fibrin monomer, as well as the pulmonary
Hirudin vom Blutegel ist ein sehr spezifischer und potenter Inhibitor des Thrombins. Das Protein (Mr 7100) kann gentechnologisch (r-Hirudin) hergestellt warden und verhalt sich wie die Substanz vom Egel. Durch Gabe von Endotoxin kann beim Schwein ein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cfc171e3c75622f3b9795ad235da806
https://doi.org/10.1007/978-3-642-73472-4_57
https://doi.org/10.1007/978-3-642-73472-4_57