Molecular Dynamics of 'Fuzzy' Transcriptional Activator-Coactivator Interactions

Autor: Scholes, NS, Weinzierl, ROJ

Transcriptional activation domains (ADs) are generally thought to be intrinsically unstructured, but capable of adopting limited secondary structure upon interaction with a coactivator surface. The indeterminate nature of this interface made it hithe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::6c1ea6c8c4ceae5c8066a622350ff357
http://hdl.handle.net/10044/1/31667

Transcribing Genes the Hard Way: In Vitro Reconstitution of Nanoarchaeal RNA Polymerase Reveals Unusual Active Site Properties.

Autor: Nottebaum S; Department of Life Sciences, Imperial College London, London, United Kingdom.; Orthomol Pharmazeutische Vertriebs GmbH, Langenfeld, Germany., Weinzierl ROJ; Department of Life Sciences, Imperial College London, London, United Kingdom.

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Multivalent and Bidirectional Binding of Transcriptional Transactivation Domains to the MED25 Coactivator.

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An Amino Acid Substitution in RNA Polymerase That Inhibits the Utilization of an Alternative Sigma Factor.

Autor: Wang Erickson AF; Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA., Deighan P; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Biology, Emmanuel College, Boston, Massachusetts, USA., Garcia CP; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.; Department of Biology, Emmanuel College, Boston, Massachusetts, USA., Weinzierl ROJ; Department of Life Sciences, Imperial College London, London, United Kingdom., Hochschild A; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA., Losick R; Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA losick@mcb.harvard.edu.

Publikováno v: Journal of bacteriology [J Bacteriol] 2017 Jun 27; Vol. 199 (14). Date of Electronic Publication: 2017 Jun 27 (Print Publication: 2017).

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