Zobrazeno 1 - 10
of 848
pro vyhledávání: '"Weinstein John N"'
Autor:
Reinhold William, Larionov Vladimir L, Brooks Brian P, Brown Jacob D, Bonner Robert F, Rajapakse Vinodh N, Ehler Martin, Kahn Ari B, Liu Hongfang, Zeeberg Barry R, Weinstein John N, Pommier Yves G
Publikováno v:
BMC Bioinformatics, Vol 12, Iss 1, p 52 (2011)
Abstract Background The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such as GoMiner can leverage GO to perform ontological analysis of
Externí odkaz:
https://doaj.org/article/bbc759ecd3f44d989fa98392806c20e7
Autor:
Reinhold William C, Chary Krishna K, Kane David, Sunshine Margot, Varma Sudhir, Shankavaram Uma T, Pommier Yves, Weinstein John N
Publikováno v:
BMC Genomics, Vol 10, Iss 1, p 277 (2009)
Abstract Background Advances in the high-throughput omic technologies have made it possible to profile cells in a large number of ways at the DNA, RNA, protein, chromosomal, functional, and pharmacological levels. A persistent problem is that some cl
Externí odkaz:
https://doaj.org/article/1c69d1c793b04f91806d074cfc3e69d2
Autor:
Liu Hongfang, Cleland James A, Kahn Ari B, Caplen Natasha J, Zeeberg Barry R, Ryan Michael C, Weinstein John N
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 313 (2008)
Abstract Background Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant challenges for contemporary biological assays. For example, RT-PCR
Externí odkaz:
https://doaj.org/article/da65e31737de47a59630943b563b9e13
Autor:
Gress Thomas M, Buchholz Malte, Kraus Johann M, Müller André, Kestler Hans A, Liu Hongfang, Kane David W, Zeeberg Barry R, Weinstein John N
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 67 (2008)
Abstract Background Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) database via GoMiner. Directed acyclic graph representations, which
Externí odkaz:
https://doaj.org/article/71cbb71b2ea240678f3491eaf701767b
Autor:
Liu Hongfang, Ryan Michael C, Kahn Ari B, Zeeberg Barry R, Jamison D Curtis, Weinstein John N
Publikováno v:
BMC Bioinformatics, Vol 8, Iss 1, p 75 (2007)
Abstract Background There are many fewer genes in the human genome than there are expressed transcripts. Alternative splicing is the reason. Alternatively spliced transcripts are often specific to tissue type, developmental stage, environmental condi
Externí odkaz:
https://doaj.org/article/7b40f370e1404a378d96b5bcefa6906b
Autor:
Shankavaram Uma, Rowland Rick, Sunshine Margot, Morita Daisaku, Nishizuka Satoshi, Major Sylvia M, Washburn Frank, Asin Daniel, Kouros-Mehr Hosein, Kane David, Weinstein John N
Publikováno v:
BMC Bioinformatics, Vol 7, Iss 1, p 192 (2006)
Abstract Background Monoclonal antibodies are used extensively throughout the biomedical sciences for detection of antigens, either in vitro or in vivo. We, for example, have used them for quantitation of proteins on "reverse-phase" protein lysate ar
Externí odkaz:
https://doaj.org/article/9f5e298d81ef4dd4b01a37079a153c0c
Autor:
Weinstein John N, Reimers Mark
Publikováno v:
BMC Bioinformatics, Vol 6, Iss 1, p 166 (2005)
Abstract Background Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifactually high or low intensities (or ratios in a two-channel arra
Externí odkaz:
https://doaj.org/article/b157232c89564ba3b35b06e170ceb155
Autor:
Wynn Thomas A, Hari Danielle M, Elnekave Eldad, Burt Stanley K, Bryant David, Stephens Robert M, Reimers Mark, Kane David W, Cao Hong, Sunshine Margot, Narasimhan Sudarshan, Qin Haiying, Zeeberg Barry R, Cunningham-Rundles Charlotte, Stewart Donn M, Nelson David, Weinstein John N
Publikováno v:
BMC Bioinformatics, Vol 6, Iss 1, p 168 (2005)
Abstract Background We previously developed GoMiner, an application that organizes lists of 'interesting' genes (for example, under-and overexpressed genes from a microarray experiment) for biological interpretation in the context of the Gene Ontolog
Externí odkaz:
https://doaj.org/article/c785a5d9cb514851a6022dfe0f655b0f
Autor:
Barrett J Carl, Linehan W Marston, Uchio Edward, Bussey Kimberly J, Riss Joseph, Kane David W, Zeeberg Barry R, Weinstein John N
Publikováno v:
BMC Bioinformatics, Vol 5, Iss 1, p 80 (2004)
Abstract Background When processing microarray data sets, we recently noticed that some gene names were being changed inadvertently to non-gene names. Results A little detective work traced the problem to default date format conversions and floating-
Externí odkaz:
https://doaj.org/article/c4dc242937f74d229cd48ceb183d9e39
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway
Autor:
Arora, Kanika, Shah, Minita, Shelton, Jennifer, Bowlby, Reanne, Friedl, Verena, Goldman, Mary, Craft, Brian, Heiman, David I., Hajirasouliha, Iman, Ricketts, Camir, Anur, Pavana, Chiotti, Kami E., Caesar-Johnson, Samantha J., Demchok, John A., Ferguson, Martin L., Kemal, Anab, Tarnuzzer, Roy, Wang, Zhining, Yang, Liming, Spellman, Paul T., Raphael, Benjamin, Akbani, Rehan, Zhu, Jingchun, Jones, Steven J.M., Shen, Hui, Carrot-Zhang, Jian, Yao, Xiaotong, Devarakonda, Siddhartha, Deshpande, Aditya, Damrauer, Jeffrey S., Silva, Tiago Chedraoui, Wong, Christopher K., Choi, Hyo Young, Felau, Ina, Robertson, A. Gordon, Castro, Mauro A.A., Bao, Lisui, Rheinbay, Esther, Liu, Eric Minwei, Trieu, Tuan, Haan, David, Yau, Christina, Hinoue, Toshinori, Liu, Yuexin, Shapira, Ofer, Kumar, Kiran, Mungall, Karen L., Zhang, Hailei, Lee, Jake June-Koo, Berger, Ashton, Gao, Galen F., Zhitomirsky, Binyamin, Liang, Wen-Wei, Zhou, Meng, Moorthi, Sitapriya, Berger, Alice H., Collisson, Eric A., Zody, Michael C., Ding, Li, Cherniack, Andrew D., Getz, Gad, Elemento, Olivier, Benz, Christopher C., Stuart, Josh, Zenklusen, J.C., Beroukhim, Rameen, Chang, Jason C., Campbell, Joshua D., Hayes, D. Neil, Yang, Lixing, Laird, Peter W., Weinstein, John N., Kwiatkowski, David J., Tsao, Ming S., Travis, William D., Khurana, Ekta, Berman, Benjamin P., Hoadley, Katherine A., Robine, Nicolas, Meyerson, Matthew, Govindan, Ramaswamy, Imielinski, Marcin
Publikováno v:
In Cell Reports 2 February 2021 34(5)