Leveraging the genetic correlation between traits improves the detection of epistasis in genome-wide association studies.

Autor: Stamp J; Center for Computational Molecular Biology, Brown University, Providence, RI 02906, USA., DenAdel A; Center for Computational Molecular Biology, Brown University, Providence, RI 02906, USA., Weinreich D; Center for Computational Molecular Biology, Brown University, Providence, RI 02906, USA.; Department of Ecology, Evolution, and Organismal Biology, Brown University, Providence, RI 02906, USA., Crawford L; Center for Computational Molecular Biology, Brown University, Providence, RI 02906, USA.; Department of Biostatistics, Brown University, Providence, RI 02903, USA.; Microsoft Research New England, Cambridge, MA 02142, USA.

Publikováno v: G3 (Bethesda, Md.) [G3 (Bethesda)] 2023 Aug 09; Vol. 13 (8).

Clinical Benefits of First-Line (1L) Cemiplimab Monotherapy by PD-L1 Expression Levels in Patients With Advanced NSCLC

Autor: Kilickap, S., Sezer, A., Gumus, M., Bondarenko, I., Ozguroglu, M., Gogishvili, M., Turk, H. M., Cicin, I., Bentsion, D., Gladkov, O., Clingan, P., Sriuranpong, V., Rizvi, N., Li, S., Lee, S., Makharadze, T., Paydas, S., Nechaeva, M., Seebach, F., Weinreich, D. M., Yancopoulos, G. D., Gullo, G., Lowy, I., Rietschel, P.

Publikováno v: Publons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::00470c3ec0ce402b86577607f17d8da3
http://hdl.handle.net/20.500.12645/28836

Diabetes mellitus differently affects electrical membrane properties of vagal afferent neurons of rats.

Autor: da Silva-Alves KS; Laboratory of Electrophysiology, Superior Institute of Biomedical Sciences, State University of Ceará, Fortaleza, Brazil., Ferreira-da-Silva FW; Laboratory of Electrophysiology, Superior Institute of Biomedical Sciences, State University of Ceará, Fortaleza, Brazil.; Technological and Exact Science Center, State University Vale do Acaraú, Sobral, Brazil., Coelho-de-Souza AN; Laboratory of Electrophysiology, Superior Institute of Biomedical Sciences, State University of Ceará, Fortaleza, Brazil.; Laboratory of Experimental Physiology, Superior Institute of Biomedical Sciences, State University of Ceará, Fortaleza, Brazil., Weinreich D; Department of Pharmacology, University of Maryland, School of Medicine, Baltimore, Maryland, USA., Leal-Cardoso JH; Laboratory of Electrophysiology, Superior Institute of Biomedical Sciences, State University of Ceará, Fortaleza, Brazil.

Publikováno v: Physiological reports [Physiol Rep] 2023 Feb; Vol. 11 (4), pp. e15605.

Characterization of the vasodilator effect of eugenol in isolated human umbilical cord arteries.

Autor: Dantas DM; Biological Chemistry Department, Postgraduate Program in Biological Chemistry, Regional University of Cariri, Pimenta Campus, 63105-010, Crato, CE, Brazil; Biological Sciences Department, Physiopharmacology of Excitable Cells Laboratory, Regional University of Cariri, Campus of Pimenta, 63105-010, Crato, CE, Brazil., Silva AA; Biological Sciences Department, Physiopharmacology of Excitable Cells Laboratory, Regional University of Cariri, Campus of Pimenta, 63105-010, Crato, CE, Brazil., Pereira-de-Morais L; Biological Sciences Department, Physiopharmacology of Excitable Cells Laboratory, Regional University of Cariri, Campus of Pimenta, 63105-010, Crato, CE, Brazil. Electronic address: luispereira256@gmail.com., Bastos CMS; Biological Chemistry Department, Postgraduate Program in Biological Chemistry, Regional University of Cariri, Pimenta Campus, 63105-010, Crato, CE, Brazil; Biological Sciences Department, Physiopharmacology of Excitable Cells Laboratory, Regional University of Cariri, Campus of Pimenta, 63105-010, Crato, CE, Brazil., Calixto GL; Biological Sciences Department, Physiopharmacology of Excitable Cells Laboratory, Regional University of Cariri, Campus of Pimenta, 63105-010, Crato, CE, Brazil., Kerntopf MR; Biological Chemistry Department, Postgraduate Program in Biological Chemistry, Regional University of Cariri, Pimenta Campus, 63105-010, Crato, CE, Brazil., Menezes IRA; Biological Chemistry Department, Postgraduate Program in Biological Chemistry, Regional University of Cariri, Pimenta Campus, 63105-010, Crato, CE, Brazil., Weinreich D; University of Maryland, Baltimore, MD, 21201, USA., Barbosa R; Biological Chemistry Department, Postgraduate Program in Biological Chemistry, Regional University of Cariri, Pimenta Campus, 63105-010, Crato, CE, Brazil; Biological Sciences Department, Physiopharmacology of Excitable Cells Laboratory, Regional University of Cariri, Campus of Pimenta, 63105-010, Crato, CE, Brazil.

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2022 May 25; Vol. 359, pp. 109890. Date of Electronic Publication: 2022 Mar 19.

Response to the correspondence: "Non-optimal methodology questions indirect treatment comparison of dupilumab vs other biologics in severe asthma".

Autor: Bateman ED; Division of Pulmonology, Department of Medicine, University of Cape Town, Cape Town, South Africa. Electronic address: eric.bateman@uct.ac.za., Khan AH; Sanofi, Chilly-Mazarin, France., Xu Y; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Guyot P; Sanofi, Chilly-Mazarin, France., Chao J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Kamat S; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Rowe P; Sanofi, Bridgewater, NJ, USA., Burnett H; Evidera, St-Laurent, Quebec, Canada., Msihid J; Sanofi, Chilly-Mazarin, France., Weinreich D; Regeneron Pharmaceuticals, Inc., Tarrytown, NY, USA., Pavord ID; Oxford Respiratory NIHR BRC, Nuffield Department of Medicine, University of Oxford, Oxford, UK.

Publikováno v: Respiratory medicine [Respir Med] 2022 Jan; Vol. 191, pp. 106088. Date of Electronic Publication: 2020 Jul 09.