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Selective Eradication of Colon Cancer Cells Harboring PI3K and/or MAPK Pathway Mutations in 3D Culture by Combined PI3K/AKT/mTOR Pathway and MEK Inhibition.

Autor: Atanasova VS; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Riedl A; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Strobl M; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Flandorfer J; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Unterleuthner D; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Weindorfer C; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Neuhold P; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Stang S; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Hengstschläger M; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria., Bergmann M; Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.; Members of the Comprehensive Cancer Center Vienna, Medical University of Vienna, 1090 Vienna, Austria., Dolznig H; Institute of Medical Genetics, Medical University of Vienna, Währinger Straße 10, 1090 Vienna, Austria.; Members of the Comprehensive Cancer Center Vienna, Medical University of Vienna, 1090 Vienna, Austria.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jan 14; Vol. 24 (2). Date of Electronic Publication: 2023 Jan 14.

MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity.

Autor: Peirsman A; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium.; Plastic, Reconstructive and Aesthetic Surgery, Ghent University Hospital, Ghent, Belgium., Blondeel E; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Ahmed T; Wallace H Coulter Department of Biomedical Engineering and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology and Emory School of Medicine, Atlanta, GA, USA., Anckaert J; OncoRNALab, Cancer Research Institute, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Audenaert D; VIB Screening Core and Ghent University Expertise Centre for Bioassay Development and Screening (C-BIOS-VIB), Ghent University, Ghent, Belgium., Boterberg T; Department of Radiation Oncology, Ghent University Hospital, Ghent, Belgium., Buzas K; Department of Immunology, University of Szeged, Faculty of Medicine-Faculty of Science and Informatics, Szeged, Hungary., Carragher N; Institute of Genetics and Cancer, Cancer Research UK Edinburgh Centre, University of Edinburgh, Edinburgh, UK., Castellani G; Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy., Castro F; i3S - Institute for Research and Innovation in Health, University of Porto, Porto, Portugal., Dangles-Marie V; Translational Research Department, Institut Curie, PSL Research University, and Faculty of Pharmacy, Paris, France.; Faculty of Pharmacy, Université Paris Descartes, Paris, France., Dawson J; Institute of Genetics and Cancer, Cancer Research UK Edinburgh Centre, University of Edinburgh, Edinburgh, UK., De Tullio P; Center for Interdisciplinary Research on Medicines (CIRM), Metabolomics Group, Université de Liège, Liège, Belgium., De Vlieghere E; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Dedeyne S; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Depypere H; Menopause and Breast Clinic, Ghent University Hospital, Ghent, Belgium., Diosdi A; Synthetic and Systems Biology Unit, Hungarian Academy of Sciences, Biological Research Center (BRC), Szeged, Hungary., Dmitriev RI; Tissue Engineering and Biomaterials Group, Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Dolznig H; Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria., Fischer S; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Gespach C; INSERM U938 Hospital Saint-Antoine Research Center CRSA, Team Céline Prunier, TGFbeta Signaling in Cellular Plasticity and Cancer, Sorbonne University, Paris, France., Goossens V; VIB Screening Core and Ghent University Expertise Centre for Bioassay Development and Screening (C-BIOS-VIB), Ghent University, Ghent, Belgium., Heino J; Department of Life Technologies, University of Turku, Turku, Finland., Hendrix A; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Horvath P; Synthetic and Systems Biology Unit, Hungarian Academy of Sciences, Biological Research Center (BRC), Szeged, Hungary., Kunz-Schughart LA; OncoRay - National Center for Radiation Research in Oncology, University Hospital Carl Gustav Carus Dresden, Carl Gustav Carus Faculty of Medicine at TU Dresden, and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Maes S; Plastic, Reconstructive and Aesthetic Surgery, Ghent University Hospital, Ghent, Belgium., Mangodt C; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Mestdagh P; OncoRNALab, Cancer Research Institute, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Michlíková S; OncoRay - National Center for Radiation Research in Oncology, University Hospital Carl Gustav Carus Dresden, Carl Gustav Carus Faculty of Medicine at TU Dresden, and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany., Oliveira MJ; i3S - Institute for Research and Innovation in Health, University of Porto, Porto, Portugal., Pampaloni F; Physical Biology Group, Buchmann Institute for Molecular Life Sciences (BMLS), Goethe Universität Frankfurt am Main, Frankfurt am Main, Germany., Piccinini F; IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Pinheiro C; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Rahn J; Departments of Oncology and Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Robbins SM; Departments of Oncology and Biochemistry and Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada., Siljamäki E; Department of Life Technologies, University of Turku, Turku, Finland., Steigemann P; Lead Discovery, Nuvisan ICB, Berlin, Germany., Sys G; Department of Orthopedics and Traumatology, Ghent University Hospital, Ghent University, Ghent, Belgium., Takayama S; Wallace H Coulter Department of Biomedical Engineering and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology and Emory School of Medicine, Atlanta, GA, USA., Tesei A; IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Tulkens J; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Van Waeyenberge M; Plastic, Reconstructive and Aesthetic Surgery, Ghent University Hospital, Ghent, Belgium., Vandesompele J; OncoRNALab, Cancer Research Institute, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Wagemans G; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium., Weindorfer C; Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria., Yigit N; OncoRNALab, Cancer Research Institute, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Zablowsky N; Lead Discovery, Nuvisan ICB, Berlin, Germany., Zanoni M; IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Blondeel P; Plastic, Reconstructive and Aesthetic Surgery, Ghent University Hospital, Ghent, Belgium., De Wever O; Laboratory of Experimental Cancer Research, Cancer Research Institute, Ghent, Belgium. olivier.dewever@ugent.be.; Department of Human Structure and Repair, Ghent University, Ghent, Belgium. olivier.dewever@ugent.be.

Publikováno v: Nature methods [Nat Methods] 2021 Nov; Vol. 18 (11), pp. 1294-1303. Date of Electronic Publication: 2021 Nov 01.

Myeloid Cell-Derived IL-1 Signaling Damps Neuregulin-1 from Fibroblasts to Suppress Colitis-Induced Early Repair of the Intestinal Epithelium.

Autor: Qiu, Ding^1,2 (AUTHOR) qiud5@mail2.sysu.edu.cn, Xu, Shaoting² (AUTHOR) jikle@mail2.sysu.edu.cn, Ji, Kaile² (AUTHOR), Tang, Ce^1,2,3 (AUTHOR) tangc7@mail.sysu.edu.cn

Publikováno v: International Journal of Molecular Sciences. Apr2024, Vol. 25 Issue 8, p4469. 24p.

Macrophage heterogeneity and its interactions with stromal cells in tumour microenvironment.

Autor: Cao, Liren¹ (AUTHOR), Meng, Xiaoyan¹ (AUTHOR), Zhang, Zhiyuan¹ (AUTHOR) zhzhy0502@163.com, Liu, Zhonglong¹ (AUTHOR) zhonglong021@126.com, He, Yue¹ (AUTHOR) william5218@126.com

Publikováno v: Cell & Bioscience. 2/1/2024, Vol. 14 Issue 1, p1-22. 22p.