Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Weinan Guo"'
ACSS2 enables melanoma cell survival and tumor metastasis by negatively regulating the Hippo pathway
Autor:
Baolu Zhang, Qing Zhu, Di Qu, Mao Zhao, Juan Du, Hengxiang Zhang, Hao Wang, Linhan Jiang, Xiuli Yi, Sen Guo, Huina Wang, Yuqi Yang, Weinan Guo
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
IntroductionAcetyl-CoA synthetase 2 (ACSS2), one of the enzymes that catalyze the conversion of acetate to acetyl-CoA, has been proved to be an oncogene in various cancers. However, the function of ACSS2 is still largely a black box in melanoma.Metho
Externí odkaz:
https://doaj.org/article/931d09d052ef4972aba5f246444ee4a9
Autor:
Yuqi Yang, Sijia Wang, Xiang-xu Wang, Sen Guo, Huina Wang, Qiong Shi, Yangzi Tian, Hao Wang, Tao Zhao, Hengxiang Zhang, Baolu Zhang, Tianwen Gao, Chunying Li, Xiuli Yi, Weinan Guo
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Tumor cells frequently suffer from endoplasmic reticulum (ER) stress. Previous studies have extensively elucidated the role of tumorous unfolded protein response in melanoma cells, whereas the effect on tumor immunology and the un
Externí odkaz:
https://doaj.org/article/1ca35d42680d49a9a960322fc26ee89d
Autor:
Yuqian Chang, Pan Kang, Tingting Cui, Weinan Guo, Weigang Zhang, Pengran Du, Xiuli Yi, Sen Guo, Tianwen Gao, Chunying Li, Shuli Li
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-19 (2023)
Abstract Background The activation of CD8+ T cells and their trafficking to the skin through JAK-STAT signaling play a central role in the development of vitiligo. Thus, targeting this key disease pathway with innovative drugs is an effective strateg
Externí odkaz:
https://doaj.org/article/965a199f1d41414ca6d1b92f08574ed9
Autor:
Xiuli Yi, Huina Wang, Yuqi Yang, Hao Wang, Hengxiang Zhang, Sen Guo, Jianru Chen, Juan Du, Yangzi Tian, Jingjing Ma, Baolu Zhang, Lili Wu, Qiong Shi, Tianwen Gao, Weinan Guo, Chunying Li
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-17 (2023)
Abstract Melanoma is the most lethal type of skin cancer, originating from the malignant transformation of melanocyte. While the development of targeted therapy and immunotherapy has gained revolutionary advances in potentiating the therapeutic effec
Externí odkaz:
https://doaj.org/article/87c7e97a5d9948e3adeb21bc4545118e
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Background: Wound healing is a complicated process involving multiple cell components and can help the re-establishment of the skin’s barrier function. Previous studies have pointed out that bacterial infection and sustained inflammatory reactions
Externí odkaz:
https://doaj.org/article/4ffff761096e4437bf75c6c68a07de74
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-39 (2021)
Abstract Melanoma is the most lethal skin cancer that originates from the malignant transformation of melanocytes. Although melanoma has long been regarded as a cancerous malignancy with few therapeutic options, increased biological understanding and
Externí odkaz:
https://doaj.org/article/6949cbaa2f704ccc90158175904c0eea
Publikováno v:
Mathematics, Vol 11, Iss 13, p 2987 (2023)
This paper presents an unconditionally stable integration method, which introduces a linearly implicit algorithm featuring an explicit displacement expression. The technique that is being considered integrates one Newton iteration into the mean accel
Externí odkaz:
https://doaj.org/article/506ca68fe8184823bf7c273a8722322b
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundMelanoma is a type of skin cancer, which originates from the malignant transformation of epidermal melanocytes, with extremely high lethality. Ferroptosis has been documented to be highly related to cancer pathogenesis and the effect of imm
Externí odkaz:
https://doaj.org/article/e8557f817784440cb33ecb7fed05b46f
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Melanoma results from the malignant transformation of melanocytes and accounts for the most lethal type of skin cancers. In the pathogenesis of melanoma, disordered metabolism is a hallmark characteristic with multiple metabolic paradigms involved in
Externí odkaz:
https://doaj.org/article/6c007b24f5b9450b85c86d76d90dea2b
Autor:
Hao Wang, Zhenjie Wu, Jingjing Ma, Weinan Guo, Jinyuan Ma, Sen Guo, Huina Wang, Sijia Wang, Qiong Shi, Jianru Chen, Xiuli Yi, Yuqi Yang, Tianwen Gao, Chunying Li, Weiming You, Xiangxu Wang, Yangzi Tian
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/cddcc949d9484abda1f7fef81ea20f4b