Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Weilun Ai"'
Autor:
Viswanathan Saraswathi, Weilun Ai, Vikas Kumar, Kanika Sharma, Thiyagarajan Gopal, Narendra Kumar, Harmeet Malhi, Tejasav Sehrawat, Cyrus V. Desouza
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 799 (2024)
Objective: Circulating exosome-enriched extracellular vesicles (EVs) have drawn considerable importance in obesity-related insulin-resistance (IR). We sought to compare the proteomics profile of serum exosomes from normal individuals and those with o
Externí odkaz:
https://doaj.org/article/4051e8112cfd421281ad724f8b6f1e18
Autor:
Viswanathan Saraswathi, Narendra Kumar, Weilun Ai, Thiyagarajan Gopal, Saumya Bhatt, Edward N. Harris, Geoffrey A. Talmon, Cyrus V. Desouza
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 739 (2022)
Saturated fatty acids (SFAs) are considered to be detrimental to human health. One of the SFAs, myristic acid (MA), is known to exert a hypercholesterolemic effect in mice as well as humans. However, its effects on altering adipose tissue (AT) inflam
Externí odkaz:
https://doaj.org/article/d1597676fbf74b3490c4edfb052bedad
Autor:
Viswanathan Saraswathi, Narendra Kumar, Thiyagarajan Gopal, Saumya Bhatt, Weilun Ai, Carmen Ma, Geoffrey A. Talmon, Cyrus Desouza
Publikováno v:
Biology, Vol 9, Iss 11, p 346 (2020)
Coconut oil, rich in medium-chain saturated fatty acids (MCSFA), in particular, lauric acid (LA), is known to exert beneficial metabolic effects. Although LA is the most abundant saturated fatty acid in coconut oil, the specific role of LA in alterin
Externí odkaz:
https://doaj.org/article/a0188651165948e891ec9f8335e22d4c
Publikováno v:
Physiology. 38
Alcohol-associated liver disease (ALD) is a major health issue worldwide with limited effective treatment options. Thromboxane-prostanoid receptor (TP-R), a G-protein-coupled receptor, is widely expressed in liver. Previous studies reported that an a
Publikováno v:
Alcohol Clin Exp Res
Alcohol-associated liver disease (AALD) encompasses a spectrum of liver diseases including simple steatosis, steatohepatitis, fibrosis, and cirrhosis. The adverse effects of alcohol in liver and the mechanisms by which ethanol promotes liver injury a
Autor:
Thiyagarajan Gopal, Saumya Bhatt, Cyrus Desouza, Carmen Ma, Viswanathan Saraswathi, Weilun Ai, Narendra Kumar, Geoffrey A. Talmon
Publikováno v:
Biology, Vol 9, Iss 346, p 346 (2020)
Biology
Volume 9
Issue 11
Biology
Volume 9
Issue 11
Coconut oil, rich in medium-chain saturated fatty acids (MCSFA), in particular, lauric acid (LA), is known to exert beneficial metabolic effects. Although LA is the most abundant saturated fatty acid in coconut oil, the specific role of LA in alterin
Publikováno v:
Journal of Pharmaceutical Sciences. 105:639-649
Doxorubicin (DOX) is known to induce apoptosis and necrosis in healthy tissue resulting in unwanted toxicities. To improve the ability of DOX to more specifically target tumors and minimize undesirable side effects, conjugation of DOX with epidermal
Autor:
Yongmei Liu, Jianli Duan, Xin Liu, Jing Chen, Shibin Ai, Yuan Tian, Weilun Ai, Fan Yang, Tao Jia, Zebo Huang
Publikováno v:
British Journal of Pharmacology. 168:1719-1735
Background and Purpose Induction of multidrug resistance by doxorubicin (DOX), together with non-specific toxicities, has restricted DOX-based chemotherapy. Recently, we demonstrated that DOX conjugated with an EGF receptor-binding peptide (DOX-EBP)
Autor:
Shibin, Ai, Tao, Jia, Weilun, Ai, Jianli, Duan, Yongmei, Liu, Jing, Chen, Xin, Liu, Fan, Yang, Yuan, Tian, Zebo, Huang
Publikováno v:
British journal of pharmacology. 168(7)
Induction of multidrug resistance by doxorubicin (DOX), together with non-specific toxicities, has restricted DOX-based chemotherapy. Recently, we demonstrated that DOX conjugated with an EGF receptor-binding peptide (DOX-EBP) had enhanced anticancer