Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Weiling Zhao"'
Autor:
Kexin Huang, Yun Zhang, Xiaorui Shi, Zhiqin Yin, Weiling Zhao, Liyu Huang, Fu Wang, Xiaobo Zhou
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 816-831 (2023)
Disrupted alternative polyadenylation (APA) is frequently involved in tumorigenesis and cancer progression by regulating the gene expression of oncogenes and tumor suppressors. However, limited knowledge of tumor-type- and cell-type-specific APA even
Externí odkaz:
https://doaj.org/article/1642cf163bc04531845c50e12cec599c
Publikováno v:
Genes, Vol 15, Iss 6, p 718 (2024)
Glioblastoma multiforme (GBM)is the most common and aggressive primary brain tumor. Although temozolomide (TMZ)-based radiochemotherapy improves overall GBM patients’ survival, it also increases the frequency of false positive post-treatment magnet
Externí odkaz:
https://doaj.org/article/a56f22e1f94b420aaa62b8b53a9e862e
Publikováno v:
Global Challenges, Vol 8, Iss 1, Pp n/a-n/a (2024)
Abstract The explosive growth of biomedical Big Data presents both significant opportunities and challenges in the realm of knowledge discovery and translational applications within precision medicine. Efficient management, analysis, and interpretati
Externí odkaz:
https://doaj.org/article/dd1b57c64d2a46f9b10d4aabc2d57c6f
Autor:
Jorge D. Oldan, Benjamin C. Giglio, Eric Smith, Weiling Zhao, Deeanna M. Bouchard, Marija Ivanovic, Yueh Z. Lee, Frances A. Collichio, Michael O. Meyers, Diana E. Wallack, Amber Abernethy-Leinwand, Patricia K. Long, Dimitri G. Trembath, Paul B. Googe, Madeline H. Kowalski, Anastasia Ivanova, Jennifer A. Ezzell, Nana Nikolaishvili-Feinberg, Nancy E. Thomas, Terence Z. Wong, David W. Ollila, Zibo Li, Stergios J. Moschos
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTClinical trials of combined IDO/PD1 blockade in metastatic melanoma (MM) failed to show additional clinical benefit compared to PD1-alone inhibition. We reasoned that a tryptophan-metabolizing pathway other than the kynurenine one is essentia
Externí odkaz:
https://doaj.org/article/ef023c41d8c54761886b2eb17171d130
Publikováno v:
Shuiwen dizhi gongcheng dizhi, Vol 50, Iss 4, Pp 173-184 (2023)
In order to deeply study the main controlling factors of land subsidence in the northeast of the Xiongan New Area, the layered monitoring points of Daying Town are taken as the research object, and the causes of land subsidence are discussed based on
Externí odkaz:
https://doaj.org/article/367d1f00173c4b07bc17849380d2d4f2
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of coronavirus disease 19 (COVID-19), has caused a global health crisis. Despite ongoing efforts to treat patients, there is no universal prevention or cure available.
Externí odkaz:
https://doaj.org/article/fec76b33986b4629840c9325d49b353f
Autor:
Kexin Huang, Yun Zhang, Haoran Gong, Zhengzheng Qiao, Tiangang Wang, Weiling Zhao, Liyu Huang, Xiaobo Zhou
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1011122 (2023)
Lung adenocarcinoma (LUAD) is a deadly tumor with dynamic evolutionary process. Although much endeavors have been made in identifying the temporal patterns of cancer progression, it remains challenging to infer and interpret the molecular alterations
Externí odkaz:
https://doaj.org/article/6d9b9883ecee4c8d860c7b1fe8d9fd00
Publikováno v:
Healthcare, Vol 11, Iss 18, p 2529 (2023)
Mining process models of medical behavior from electronic medical records is an effective way to optimize clinical pathways. However, clinical medical behavior is an extremely complex field with high nonlinearity and variability, and thus we need to
Externí odkaz:
https://doaj.org/article/c5e46c53995f4ba0afc9942d43cc811f
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1242 (2023)
The emergence of RNA velocity has enriched our understanding of the dynamic transcriptional landscape within individual cells. In light of this breakthrough, we embarked on integrating RNA velocity with cellular pseudotime inference, aiming to improv
Externí odkaz:
https://doaj.org/article/93684fc864ed431ebd7623805585e963
Autor:
Yujun Liu, Kai Chen, Yangyang Luo, Jiqiu Wu, Qu Xiang, Li Peng, Jian Zhang, Weiling Zhao, Mingliang Li, Xiaobo Zhou
Publikováno v:
Digital Health, Vol 8 (2022)
Background Major depressive disorder and bipolar disorder in adolescents are prevalent and are associated with cognitive impairment, executive dysfunction, and increased mortality. Early intervention in the initial stages of major depressive disorder
Externí odkaz:
https://doaj.org/article/fd2a961ad0a848c1a5e2f83b968d05dc