Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Weilin Q"'
Autor:
Yuxin Cai, Lijuan Sui, Jingjing Wang, Weilin Qian, Yeheng Peng, Luyao Gong, Weijia Wu, Yuan Gao
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background Cell and gene therapy products (CGTPs) often receive accelerated approvals, lacking comprehensive long-term safety and efficacy data, which can raise significant safety concerns. This research aims to study the post-marketing surv
Externí odkaz:
https://doaj.org/article/c9946b23617b4dcf8f586491879b709b
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionThymic stromal lymphopoietin (TSLP) is integral to inducing innate and T helper two cell inflammation that leads to clinical symptoms of asthma. SHR-1905 is a humanized immunoglobulin G1 kappa monoclonal antibody that inhibits TSLP bioact
Externí odkaz:
https://doaj.org/article/7870093938624ce0bc4da917984206c8
Publikováno v:
Experimental Gerontology, Vol 190, Iss , Pp 112428- (2024)
Background: Mitochondrial dysregulation in skeletal myocytes is considered a major factor in aged sarcopenia. In this study, we aimed to study the effects of peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) on Sestrin2-m
Externí odkaz:
https://doaj.org/article/0a499de4365c43dcbf95dd099513d139
Autor:
Na Li, Sepehr Shakib, Weilin Qian, Xiaoyan Yao, Puyuan Li, Tsz Keung Nip, Xiaoyan Bai, Kai Shen
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 4, Pp n/a-n/a (2024)
Abstract SHR‐1819 is a novel anti‐IL‐4Rα monoclonal antibody currently under clinical development for use in patients with type 2 inflammatory diseases. In this randomized, double‐blind, placebo‐controlled, single‐dose escalation phase I
Externí odkaz:
https://doaj.org/article/d758e3e40e7b488ba4dd68bb15474e5b
Autor:
Nan Xia, Yuqian Tang, Mengying Tang, Weilin Quan, Zhanjiang Xu, Bowen Zhang, Yuxuan Xiao, Yonggang Ma
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
For a long time, human activities have been prohibited in ecologically protected areas in the Ebinur Lake Wetland National Nature Reserve (ELWNNR). The implementation of total closure is one of the main methods for ecological protection. For arid zon
Externí odkaz:
https://doaj.org/article/a25e26db3196494da4381329478807ed
Publikováno v:
Ecological Indicators, Vol 154, Iss , Pp 110807- (2023)
Xinjiang is located in the northwest of China, with a vast territory and abundant resources, which holds an important strategic position for China. However, the climate in the region is arid and the ecological environment is fragile. In recent years,
Externí odkaz:
https://doaj.org/article/05f0a5421fe74b2ebe02216589a13476
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285610 (2023)
PM2.5 is closely linked to both air quality and public health. Many studies have used models combined with remote sensing and auxiliary data to inverse a large range of PM2.5 concentrations. However, the data's spatial resolution is limited. and bett
Externí odkaz:
https://doaj.org/article/9fe2186ac5744d23b1bbd2f47bf65b9a
Publikováno v:
JACS Au, Vol 1, Iss 2, Pp 156-163 (2020)
Externí odkaz:
https://doaj.org/article/ddc1a863554d443d862151e18f9d93be
Autor:
Yi Zhou, La Zhu, Yu Sun, Hui Zhang, Jiaojiao Wang, Weilin Qin, Wangchao He, Luojing Zhou, Qi Li, Rurong Zhao, Kaikun Luo, Chenchen Tang, Chun Zhang, Shaojun Liu
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Polyploidy occurs naturally in fish; however, the appearance of these species is an occasional and gradual process, which makes it difficult to trace the changes in phenotypes, genotypes, and regulation of gene expression. The allotetraploid hybrids
Externí odkaz:
https://doaj.org/article/773dc9eeb21e4af1ae234830650b80ab
Autor:
Yuting Guo, Weibo Dai, Yan Zheng, Weilin Qiao, Weixuan Chen, Lihua Peng, Hua Zhou, Tingting Zhao, Huimin Liu, Feng Zheng, Peng Sun
Publikováno v:
Molecules, Vol 27, Iss 20, p 7080 (2022)
Intracerebral hemorrhage (ICH) is the most lethal subtype of stroke, but effective treatments are lacking, and neuroinflammation plays a key role in the pathogenesis. In the innate immune response to cerebral hemorrhage, microglia first appear around
Externí odkaz:
https://doaj.org/article/5ba84a8bbf1b4d0881b59e0cad826f1d