Zobrazeno 1 - 10
of 290
pro vyhledávání: '"Weikop P"'
Publikováno v:
Translational Neuroscience, Vol 13, Iss 1, Pp 320-326 (2022)
The CACNA1C protein is a L-type calcium channel, which influence affective disorders.
Externí odkaz:
https://doaj.org/article/7773e091bf7140d2a2d6878ca73d348d
Autor:
Qian Sun, Sisi Peng, Qiwu Xu, Pia Weikop, Rashad Hussain, Wei Song, Maiken Nedergaard, Fengfei Ding
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Epileptogenesis is the process whereby the previously normally functioning brain begins to generate spontaneous, unprovoked seizures. Status epilepticus (SE), which entails a massive release of neuronal glutamate and other neuroactive substa
Externí odkaz:
https://doaj.org/article/9923f647b3e24330a44f711ec40c2199
Autor:
Neža Cankar, Natalie Beschorner, Anastasia Tsopanidou, Filippa L. Qvist, Ana R. Colaço, Mie Andersen, Celia Kjaerby, Christine Delle, Marius Lambert, Filip Mundt, Pia Weikop, Mathias Jucker, Matthias Mann, Niels Henning Skotte, Maiken Nedergaard
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114977- (2024)
Summary: Impaired sleep is a common aspect of aging and often precedes the onset of Alzheimer’s disease. Here, we compare the effects of sleep deprivation in young wild-type mice and their APP/PS1 littermates, a murine model of Alzheimer’s diseas
Externí odkaz:
https://doaj.org/article/879a38c249f7446eb3ef832e4a2b5bc5
Autor:
Christine Delle, Xiaowei Wang, Michael Giannetto, Evan Newbold, Weiguo Peng, Ryszard Stefan Gomolka, Antonio Ladrón-de-Guevara, Neža Cankar, Elise Schiøler Nielsen, Celia Kjaerby, Pia Weikop, Yuki Mori, Maiken Nedergaard
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Glymphatic transport is vital for the physiological homeostasis of the retina and optic nerve. Pathological alterations of ocular glymphatic fluid transport and enlarged perivascular spaces have been described in glaucomatous mice. It remain
Externí odkaz:
https://doaj.org/article/8a286795867f441496e4616d9e241860
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Upon both acute and prolonged alcohol intake, the brain undergoes a metabolic shift associated with increased acetate metabolism and reduced glucose metabolism, which persists during abstinence, putatively leading to energy depletion in the
Externí odkaz:
https://doaj.org/article/92808c120b834da787be070569b8e17b
Autor:
Christine Delle, Neža Cankar, Christian Digebjerg Holgersson, Helle Hvorup Knudsen, Elise Schiøler Nielsen, Celia Kjaerby, Yuki Mori, Maiken Nedergaard, Pia Weikop
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Obesity affects millions of people worldwide and is associated with an increased risk of cognitive decline. The glymphatic system is a brain-wide metabolic waste clearance system, dysfunction of which is linked to dementia. We herein examine
Externí odkaz:
https://doaj.org/article/3fe18b81296a41f69cb823c501f1ae53
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Akademický článek
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Autor:
WEIKOP, CHRISTIAN
Publikováno v:
Burlington Magazine; Sep2024, Vol. 166 Issue 1458, p965-968, 4p
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
BackgroundAlcohol use disorder (AUD) is a major problem of our society and is often characterized and worsened by relapse. Prolonged alcohol exposure leads to numerous biochemical alterations that, upon cessation of alcohol intake, cause an array of
Externí odkaz:
https://doaj.org/article/5ccb12d54ea24bc6a28d887c49ec8b02