Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Weikaixin Kong"'
Autor:
Sujie Zhu, Wenjing Zhu, Kaihua Zhao, Jie Yu, Wenxia Lu, Rui Zhou, Shule Fan, Weikaixin Kong, Feifei Yang, Peipei Shan
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Background Breast cancer is one of the most lethal cancers in women. Despite significant advances in the diagnosis and treatment of breast cancer, many patients still succumb to this disease, and thus, novel effective treatments are urgently
Externí odkaz:
https://doaj.org/article/79cb79b9aa9b4770b8ab2665f901b61e
Autor:
Yifan Wang, Hui Yang, Na Li, Lili Wang, Chang Guo, Weining Ma, Shiqi Liu, Chao Peng, Jiexin Chen, Huifang Song, Hedan Chen, Xinyue Ma, Jingyun Yi, Jingjing Lian, Weikaixin Kong, Jie Dong, Xinyu Tu, Mala Shah, Xin Tian, Zhuo Huang
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract Intrinsic plasticity, a fundamental process enabling neurons to modify their intrinsic properties, plays a crucial role in shaping neuronal input‐output function and is implicated in various neurological and psychiatric disorders. Despite
Externí odkaz:
https://doaj.org/article/4dc7b2a5320f4ffe9666be2212827c47
Autor:
Aleksandra Urban, Johanne Hermansen, Yanping Yin, Weikaixin Kong, Rebecca Teglgaard, Christian Brieghel, Sabina Kersting, Geir E. Tjønnfjord, Mark-David Levin, Hoa T. T. Tran, Mattias Mattsson, Juha Ranti, Gerrit-Jan Veldhuis, Caspar Da Cunha-Bang, Rogier Mous, Julie Dubois, Arnon Kater, Carsten Niemann, Tero Aittokallio, Sigrid Skånland
Publikováno v:
HemaSphere, Vol 7, p e92046ec (2023)
Externí odkaz:
https://doaj.org/article/69ae2e40c7fe4a2ca9baae0e3b9e3035
Publikováno v:
iMeta, Vol 2, Iss 3, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/5648be5dd9094ebe9ca2716488a8ac4a
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundColon cancer is a highly heterogeneous disease, and identifying molecular subtypes can provide insights into deregulated pathways within tumor subsets, which may lead to personalized treatment options. However, most prognostic models are ba
Externí odkaz:
https://doaj.org/article/1c41b5ce181545b9bac4db4ca8d5dcdf
Autor:
Jie Zhu, Weikaixin Kong, Liting Huang, Shixin Wang, Suzhen Bi, Yin Wang, Peipei Shan, Sujie Zhu
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6412-6426 (2022)
The molecular landscape in breast cancer is characterized by large biological heterogeneity and variable clinical outcomes. Here, we performed an integrative multi-omics analysis of patients diagnosed with breast cancer. Using transcriptomic analysis
Externí odkaz:
https://doaj.org/article/c14580694e68492aa2b13cfdbd20f434
Autor:
Weikaixin Kong, Gianmarco Midena, Yingjia Chen, Paschalis Athanasiadis, Tianduanyi Wang, Juho Rousu, Liye He, Tero Aittokallio
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2807-2814 (2022)
Synergistic effects between drugs are rare and highly context-dependent and patient-specific. Hence, there is a need to develop novel approaches to stratify patients for optimal therapy regimens, especially in the context of personalized design of co
Externí odkaz:
https://doaj.org/article/175a067dc4514c28b5498d1175b594cd
Autor:
Linzhi Tan, Zhaohui Zheng, Yuanwei Xu, Weikaixin Kong, Zhen Dai, Xuewen Qin, Tao Liu, Hongting Tang
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
With the advances in the field of expanded genetic code, the application of non-canonical amino acid (ncAA) is considered an effective strategy for protein engineering. However, cumbersome and complicated selection schemes limit the extensive applica
Externí odkaz:
https://doaj.org/article/f3396eaa86c944c9ae62ac727f127504
Publikováno v:
Journal of Cellular and Molecular Medicine. 27:266-276
Na(v)1.5 sodium channels contribute to the generation of the rapid upstroke of the myocardial action potential and thereby play a central role in the excitability of myocardial cells. At present, the patch clamp method is the gold standard for ion ch
Autor:
Jie Zhu, Yongpan An, Xin Wang, Liting Huang, Weikaixin Kong, Miaomiao Gao, Jingxiang Wang, Xinpei Sun, Sujie Zhu, Zhengwei Xie
Publikováno v:
Life Medicine. 1:372-386
The occurrence of obesity is associated with age. But their interplay remains mysterious. Here, we discovered that rotundic acid (RA), a plant-derived pentacyclic triterpene, was a powerful agent for both anti-aging and treating obesity. Considering