Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Weiji Zhang"'
SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling
Autor:
Dongxue Su, Yuxi Li, Weiji Zhang, Huan Gao, Yao Cheng, Yongqiang Hou, Junhong Li, Yi Ye, Zhangjian Lai, Zhe Li, Haitao Huang, Jiaxin Li, Jinhuan Li, Mengyu Cheng, Cheng Nian, Na Wu, Zhien Zhou, Yunzhi Xing, Yu Zhao, He Liu, Jiayu Tang, Qinghua Chen, Lixin Hong, Wengang Li, Zhihai Peng, Bin Zhao, Randy L. Johnson, Pingguo Liu, Wanjin Hong, Lanfen Chen, Dawang Zhou
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 20 (2023)
The loss of contact inhibition is a key step during carcinogenesis. The Hippo–Yes-associated protein (Hippo/YAP) pathway is an important regulator of cell growth in a cell density–dependent manner. However, how Hippo signaling senses cell density
Externí odkaz:
https://doaj.org/article/10851ccf1c0d4b83bc5cb1bf57cbefc0
Publikováno v:
PeerJ, Vol 8, p e10148 (2020)
Smad nuclear interacting protein 1 (SNIP1) is a nuclear protein and involved in essential biological processes. MicroRNAs are effective regulators of tumorigenesis and cancer progression via targeting multiple genes. In present study, we aimed to inv
Externí odkaz:
https://doaj.org/article/c02ae6d368db472283f3ea771658137a
Publikováno v:
Atmosphere, Vol 10, Iss 8, p 472 (2019)
Subway air pollution mainly refers to inhalable particulate matter (PM) pollution, organic pollution, and microbial pollution. Based on the investigation and calculation of the existing researches, this paper summarizes the sources of air pollutants,
Externí odkaz:
https://doaj.org/article/bcbddda11ec341babeeae78049fa25b1
Autor:
Hui Shao, Cheng Nian, Dawang Zhou, Jing Geng, Jin Ding, Yuxi Li, Xianming Deng, Weiji Zhang, Hao Zhao, Shuhai Lin, Chen Xiao, Lihong Chen, Qian Zhao, Randy L. Johnson, Shihao Zhang, Qingxu Liu, Xiaolong Liu, Dongxue Su, Lixin Hong, Qinghua Chen, Junhong Li, Qiao Wu, Lanfen Chen, Jiaxin Li, Rongqin Ke
Publikováno v:
Cell. 184(22)
Glucose consumption is generally increased in tumor cells to support tumor growth. Interestingly, we report that glycogen accumulation is a key initiating oncogenic event during liver malignant transformation. We found that glucose-6-phosphatase (G6P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8308f850b4464cf2d3c3a8d36f8a0294
https://pubmed.ncbi.nlm.nih.gov/34861187
https://pubmed.ncbi.nlm.nih.gov/34861187
Publikováno v:
Atmosphere, Vol 10, Iss 8, p 472 (2019)
Atmosphere
Volume 10
Issue 8
Atmosphere
Volume 10
Issue 8
Subway air pollution mainly refers to inhalable particulate matter (PM) pollution, organic pollution, and microbial pollution. Based on the investigation and calculation of the existing researches, this paper summarizes the sources of air pollutants,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e478789a90c6fa7245b3e2ca575f0094
https://www.mdpi.com/2073-4433/10/8/472
https://www.mdpi.com/2073-4433/10/8/472
Autor:
Suyuan Ji, Daming Gao, Chengyan Liu, Dawang Zhou, Qiao Wu, Keiko Nakayama, Jing Geng, Qiyuan Li, Lixin Hong, Shihao Zhang, Xianming Deng, Kwang Huei Lin, Keiichi I. Nakayama, Yuanyuan Zeng, Lanfen Chen, Qingxu Liu, Qinghua Chen, Weiji Zhang, Liang Zhu, Zhonglei Lu, Zhenyu Yin, Xiufeng Sun, Randy L. Johnson, Yuxi Li
Polyploidy can lead to aneuploidy and tumorigenesis. Here, we report that the Hippo pathway effector Yap promotes the diploid-polyploid conversion and polyploid cell growth through the Akt-Skp2 axis. Yap strongly induces the acetyltransferase p300-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b749080e45476fc11c8cb09259ba2a
https://europepmc.org/articles/PMC5863541/
https://europepmc.org/articles/PMC5863541/
Autor:
Yuan Zhu, Shiquan Ling, Xuchun Gui, Lifang Yuan, Zikang Tang, Rong Xiang, Tianzhun Wu, Weiji Zhang
Publikováno v:
J. Mater. Chem. A. 2:6952-6959
This paper proposes a facile, versatile, and low-cost approach for batch production of engineered superlyophobic surfaces (SLSs, simultaneously superhydrophobic and superoleophobic) on various curable materials. Based on the soft replication using po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c36823007e27ab708abed3468f4b8af
https://doi.org/10.1039/c4ta00672k
https://doi.org/10.1039/c4ta00672k
Autor:
Dawang Zhou, Qingxu Liu, Shihao Zhang, Qiao Wu, Li Wang, Cong Wang, Changchuan Xie, Cheng Nian, Yuxi Li, Zhenyu Yin, Ying He, Chen Xiao, Jiaxin Li, Fen Wang, Weiji Zhang, Lixin Hong, Lanfen Chen, Qinghua Chen, Junhong Li, Randy L. Johnson, Suyuan Ji, Jing Geng, Han You, Chundong Yu, Kwang Huei Lin, Xing Chen, Xun Li
Publikováno v:
Developmental Cell. 48:460-474.e9
Summary The external factors that modulate Hippo signaling remain elusive. Here, we report that FGF15 activates Hippo signaling to suppress bile acid metabolism, liver overgrowth, and tumorigenesis. FGF15 is induced by FXR in ileal enterocytes in res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a8ec719e8b9869bac4ce794f23a5e3
https://doi.org/10.1016/j.devcel.2018.12.021
https://doi.org/10.1016/j.devcel.2018.12.021
Publikováno v:
Wei sheng wu xue bao = Acta microbiologica Sinica. 55(11)
The work was aimed at selecting osmo-regulated prompters possessing excellent performance for further research of the industrial yeast Candida glycerinogenes.Promoters PCgPGI, PCgTPI, PCgZWF, PCgSTL1, PCgSTL2 and PCgSTL3 were amplified by PCR and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0ed2efff4625d2fca229b375cbf6918e
https://pubmed.ncbi.nlm.nih.gov/26915219
https://pubmed.ncbi.nlm.nih.gov/26915219
Autor:
Jinjin Ye, Ningshao Xia, Lixin Hong, Cai-Hong Yun, Hao Liu, Dawang Zhou, Chen Xiao, Lihong Huang, Xinrui Wu, Xiufeng Sun, Quan Yuan, Weiji Zhang, Qiao Wu, Nathanael S. Gray, Fan Fuqin, Qinghua Chen, Xianming Deng, Zhixiang He, Lanfen Chen, Shihao Zhang, Lu-Lu Kong, Yunzhan Li, Lunzhi Yuan, Jing Geng, Zhiliang Ji, Sun Xihuan, Ping Wang
Publikováno v:
Science translational medicine. 8(352)
Tissue repair and regenerative medicine address the important medical needs to replace damaged tissue with functional tissue. Most regenerative medicine strategies have focused on delivering biomaterials and cells, yet there is the untapped potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77341940a4ea1a5499c678562ca50924
https://pubmed.ncbi.nlm.nih.gov/27605063
https://pubmed.ncbi.nlm.nih.gov/27605063