Function of the ABC transporters, P-glycoprotein, multidrug resistance protein and breast cancer resistance protein, in minimal residual disease in acute myeloid leukemia

Autor: van der Pol, M.A., Broxterman, H.J., Pater, JM, Feller, N., Maas, M., Weijers, GW, Scheffer, G.L., Allen, JD, Scheper, R.J., van Loevezijn, A, Ossenkoppele, G.J., Schuurhuis, G.J.

Publikováno v: Haematologica, 88(2), 134-47. Ferrata Storti Foundation
van der Pol, M A, Broxterman, H J, Pater, JM, Feller, N, Maas, M, Weijers, GW, Scheffer, G L, Allen, JD, Scheper, R J, van Loevezijn, A, Ossenkoppele, G J & Schuurhuis, G J 2003, ' Function of the ABC transporters, P-glycoprotein, multidrug resistance protein and breast cancer resistance protein, in minimal residual disease in acute myeloid leukemia. ', Haematologica, vol. 88, no. 2, pp. 134-47 . < http://haematologica-thj.org/cgi/reprint/88/2/134.pdf >

BACKGROUND AND OBJECTIVES: Relapse is common in acute myeloid leukemia (AML) because of persistence of minimal residual disease (MRD). ABC-transporters P-glycoprotein (Pgp) and multidrug resistance protein (MRP), are thought to contribute to treatmen

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MRD parameters using immunophenotypic detection methods are highly reliable in predicting survival in acute myeloid leukaemia.

Autor: Feller N; Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands., van der Pol MA, van Stijn A, Weijers GW, Westra AH, Evertse BW, Ossenkoppele GJ, Schuurhuis GJ

Publikováno v: Leukemia [Leukemia] 2004 Aug; Vol. 18 (8), pp. 1380-90.

Function of the ABC transporters, P-glycoprotein, multidrug resistance protein and breast cancer resistance protein, in minimal residual disease in acute myeloid leukemia.

Autor: van der Pol MA; Department of Hematology, VU University Medical Center, Amsterdam, The Netherlands., Broxterman HJ, Pater JM, Feller N, van der Maas M, Weijers GW, Scheffer GL, Allen JD, Scheper RJ, van Loevezijn A, Ossenkoppele GJ, Schuurhuis GJ

Publikováno v: Haematologica [Haematologica] 2003 Feb; Vol. 88 (2), pp. 134-47.