Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Weihui Shao"'
Autor:
LeYuan Gu, WeiHui Shao, Lu Liu, Qing Xu, YuLing Wang, JiaXuan Gu, Yue Yang, ZhuoYue Zhang, YaXuan Wu, Yue Shen, Qian Yu, XiTing Lian, HaiXiang Ma, YuanLi Zhang, HongHai Zhang
Publikováno v:
eLife, Vol 13 (2024)
The advent of midazolam holds profound implications for modern clinical practice. The hypnotic and sedative effects of midazolam afford it broad clinical applicability. However, the specific mechanisms underlying the modulation of altered consciousne
Externí odkaz:
https://doaj.org/article/20ca8e0a75394714835daa95d8d3517f
Autor:
Qing Xu, YuLing Wang, XiTing Lian, Lu Liu, WeiHui Shao, JiaXuan Gu, LeYuan Gu, Qian Yu, YuanLi Zhang, ZhuoYue Zhang, HaiXiang Ma, Yue Shen, HongHai Zhang
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102403- (2023)
Summary: The locus coeruleus (LC) and noradrenergic neurotransmission are involved in the regulation of sudden unexpected death in epilepsy (SUDEP). Here, we present a protocol for modulating the noradrenergic pathway from LC to heart to prevent SUDE
Externí odkaz:
https://doaj.org/article/8c72f32a5717468ea66244f275d37378
Autor:
XiTing Lian, Qing Xu, YuLing Wang, LeYuan Gu, Qian Yu, WeiHui Shao, HaiXiang Ma, Yue Shen, Lu Liu, JiaXuan Gu, HongHai Zhang
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106284- (2023)
Summary: Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among epilepsy patients. However, the underlying mechanism remains elusive. Seizure-induced respiratory arrest (S-IRA) is recognized as a main cause of SUDEP, but the
Externí odkaz:
https://doaj.org/article/560f0abfe75a419e9da826703f82df82
Autor:
YuLing Wang, Qing Xu, Qian Yu, LeYuan Gu, HaiXiang Ma, Yue Shen, XiTing Lian, WeiHui Shao, JiaXuan Gu, Lu Liu, HongHai Zhang
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102129- (2023)
Summary: The dorsal raphe nucleus (DR) and the pre-Bötzinger complex (PBC) may play an important role in regulating seizure-induced respiratory arrest (S-IRA), the main contributor to sudden unexpected death in epilepsy. Here, we describe pharmacolo
Externí odkaz:
https://doaj.org/article/44323863adb249d8b23b64980a5b2a2c
Autor:
Zhaoyong Zhang, Eric Zeng, Lu Zhang, Weiming Wang, Yingkang Jin, Jiye Sun, Shuxiang Huang, Wenguang Yin, Jun Dai, Zhen Zhuang, Zhao Chen, Jing Sun, Airu Zhu, Fang Li, Weitao Cao, Xiaobo Li, Yongxia Shi, Mian Gan, Shengnan Zhang, Peilan Wei, Jicheng Huang, Nanshan Zhong, Guocai Zhong, Jingxian Zhao, Yanqun Wang, Weihui Shao, Jincun Zhao
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Abstract The current COVID-19 pandemic, caused by SARS-CoV-2, poses a serious public health threat. Effective therapeutic and prophylactic treatments are urgently needed. Angiotensin-converting enzyme 2 (ACE2) is a functional receptor for SARS-CoV-2,
Externí odkaz:
https://doaj.org/article/9b704b1c51eb428aae1ea4a9d75ae69c
Publikováno v:
Energies, Vol 12, Iss 15, p 2891 (2019)
Decision-making of microgrids in the condition of a dynamic uncertain bidding environment has always been a significant subject of interest in the context of energy markets. The emerging application of reinforcement learning algorithms in energy mark
Externí odkaz:
https://doaj.org/article/c13067ce146e473a8423f7d1ae8d227e
Publikováno v:
Energies, Vol 11, Iss 12, p 3312 (2018)
Networked microgrids are emerging for coordinating distributed energy resources in distribution networks in the future Energy Internet, for which developing an efficient energy market model is crucial for facilitating multi-directional trading among
Externí odkaz:
https://doaj.org/article/3f4662ff8f184f928c59643986fd6d85
Autor:
LeYuan Gu, Lu Liu, WeiHui Shao, JiaXuan Gu, Qing Xu, YuLing Wang, Qian Yu, XiTing Lian, HongHai Zhang
Generation of the unconsciousness associated with arousal during the initial stage of anesthesia by midazolam is critical for general anesthesia, however, the exact mechanism remains unknown. Here, firstly, we found that the destruction of noradrener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e2664b4ca5f8877136f1ba0dd5a3684
https://doi.org/10.1101/2023.03.20.533578
https://doi.org/10.1101/2023.03.20.533578
Autor:
Haixiang Ma, Leyuan Gu, Yuling Wang, Qing Xu, Weihui Shao, Qian Yu, Xiting Lian, Lu Liu, Jiaxuan Gu, Na Ji, Yuanli Zhang, Xiaoling Liu, Kazuki Nagayasu, Honghai Zhang
General anesthesia is widely used in various clinical practices due to its ability to cause loss of consciousness. However, the exact mechanism of anesthesia-induced unconsciousness remains unclear. It is generally thought that arousal-related brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69ee5432131b95648ce32dac32cdafaa
https://doi.org/10.21203/rs.3.rs-2665304/v1
https://doi.org/10.21203/rs.3.rs-2665304/v1
Autor:
HaiXiang Ma, LeYuan Gu, YuLing Wang, Qing Xu, Qian Yu, XiTing Lian, WeiHui Shao, Lu Liu, JiaXuan Gu, Yue Shen, HongHai Zhang
In order to explore the mechanism of general anesthesia emergence, based on the common clinical phenomenon-delayed emergence, we explore the role of 5-hydroxytryptamine (5-HT) neurons in the dorsal raphe nucleus in promoting awakening from sevofluran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e26ee2c5762d7904ba8b2c96cfa1882
https://doi.org/10.1101/2022.05.22.492958
https://doi.org/10.1101/2022.05.22.492958