Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Weihua Shou"'
Autor:
Yanjun Wang, Ling Hang, Weihua Shou, Cuifen Li, Fangling Dong, Xingxing Feng, Ruohong Jin, Bin Li, Shufang Xiao
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
BackgroundThere are few reports of infantile mitochondrial DNA depletion syndrome (MDDS) caused by variants in RRM2B and the correlation between genotype and phenotype has rarely been analyzed in detail. This study investigated an infantile patient w
Externí odkaz:
https://doaj.org/article/4c9a4b538e6b40a19daa0546d7dc81b2
Autor:
Yanjun Wang, Juan He, Fangling Dong, Weihua Shou, Xingxing Feng, Ya Yang, Cuifen Li, Jingjing Wang, Bin Li, Shufang Xiao
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e27199- (2024)
Background: Combined Oxidative Phosphorylation Deficiency 23 (COXPD23) is a rare mitochondrial disease caused by mutations in the GTPBP3 gene. The rare incidence of the disease and the high clinical heterogeneity pose challenges in making a precise d
Externí odkaz:
https://doaj.org/article/46aea6830ec34a51a1caf63b637448f9
Autor:
Cassandra N Spracklen, Jinxiu Shi, Swarooparani Vadlamudi, Ying Wu, Meng Zou, Chelsea K Raulerson, James P Davis, Monica Zeynalzadeh, Kayla Jackson, Wentao Yuan, Haifeng Wang, Weihua Shou, Ying Wang, Jingchun Luo, Leslie A Lange, Ethan M Lange, Barry M Popkin, Penny Gordon-Larsen, Shufa Du, Wei Huang, Karen L Mohlke
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007275 (2018)
To identify genetic contributions to type 2 diabetes (T2D) and related glycemic traits (fasting glucose, fasting insulin, and HbA1c), we conducted genome-wide association analyses (GWAS) in up to 7,178 Chinese subjects from nine provinces in the Chin
Externí odkaz:
https://doaj.org/article/2f4c9552e17c4607a5f338d225ffa92d
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46295 (2012)
In order to comprehensively screen genetic variants leading to differential expression of the important human ABCB1 gene in the primary drug-metabolizing organ, ABCB1 mRNA expression levels were measured in 73 normal liver tissue samples from Chinese
Externí odkaz:
https://doaj.org/article/e7f89663c2894a1ab9d26fc532ec6be3
Autor:
Dazhi Wang, Zhengwen Jiang, Zhongyang Shen, Hui Wang, Beilan Wang, Weihua Shou, Hong Zheng, Xun Chu, Jinxiu Shi, Wei Huang
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24900 (2011)
Variations in the activities of Cytochrome P450s are one of the major factors responsible for inter-individual differences in drug clearance rates, which may cause serious toxicity or inefficacy of therapeutic drugs. Various mRNA level is one of the
Externí odkaz:
https://doaj.org/article/f14d46bf6a5e4e8cb168d558f9ee467e
Publikováno v:
Journal of Genetics and Genomics. 47:756-769
The unusual chromosome 11q23.3 harboring the apolipoprotein (APO) gene cluster has been well documented for its essential roles in plasma lipid-related traits and atherosclerotic cardiovascular diseases. However, its genetic architecture and the pote
Publikováno v:
Biochemical Genetics. 49:122-137
This haplotype-based case-control study investigated whether the aldosterone synthase gene (CYP11B2) might be implicated in the pathogenesis of essential hypertension in Yi (226 individuals) and Hani (296 individuals) minorities of China. Four tag SN
Autor:
Penny Gordon-Larsen, Ying Wang, Ethan M. Lange, Shi Jinxiu, Shufa Du, Wentao Yuan, Meng Zou, Cassandra N. Spracklen, Leslie A. Lange, Chelsea K. Raulerson, Wei Huang, Karen L. Mohlke, Jingchun Luo, Haifeng Wang, Swarooparani Vadlamudi, Barry M. Popkin, Weihua Shou, James P. Davis, Ying Wu, Kayla Jackson, Monica Zeynalzadeh
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 4, p e1007275 (2018)
PLoS Genetics, Vol 14, Iss 4, p e1007275 (2018)
To identify genetic contributions to type 2 diabetes (T2D) and related glycemic traits (fasting glucose, fasting insulin, and HbA1c), we conducted genome-wide association analyses (GWAS) in up to 7,178 Chinese subjects from nine provinces in the Chin
Autor:
Ying Wang, Fang Xie, Yi Wang, Wei Huang, Hong Wu, Shi Jinxiu, Zhi-Min Wang, Beilan Wang, Lin Yang, Weihua Shou
Publikováno v:
Biochimica et biophysica acta. 1842(11)
Apolipoprotein A5 (APOA5) gene plays a key role in plasma triglyceride (TG) metabolism, and shows the involvement in coronary artery disease (CAD). A set of single nucleotide polymorphisms around the APOA5 gene was identified to be associated with pl
Autor:
Wei Huang, Lin Liu, Xiao-Jing Miao, Haifeng Wang, Ya-Nan Bai, Kai-Yue Zhang, Fang Xie, Peng-Peng Yang, Weihua Shou, Min Shen, Huai-Dong Song, Yan Dong, Sai-Juan Chen, Qi Hua, Xun Chu, Zhu Chen, Lin Yang, Wen-Dong Liu, Yi Wang, Shi Jinxiu
Publikováno v:
Journal of Medical Genetics
Background Graves’ disease is a female preponderant autoimmune illness and the contribution of the X chromosome to its risk has long been appreciated. However, no X-linked susceptibility loci have been indentified from recent genome-wide associatio