A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia

Autor: Tooba Quidwai, Jiaolong Wang, Emma A Hall, Narcis A Petriman, Weihua Leng, Petra Kiesel, Jonathan N Wells, Laura C Murphy, Margaret A Keighren, Joseph A Marsh, Esben Lorentzen, Gaia Pigino, Pleasantine Mill

Publikováno v: eLife, Vol 10 (2021)

Intraflagellar transport (IFT) is a highly conserved mechanism for motor-driven transport of cargo within cilia, but how this cargo is selectively transported to cilia is unclear. WDR35/IFT121 is a component of the IFT-A complex best known for its ro

Externí odkaz: https://doaj.org/article/a1c4b4199b71449c8dc737a7d2b3ac26

Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells

Autor: Elisabeth Nüske, Guendalina Marini, Doris Richter, Weihua Leng, Aliona Bogdanova, Titus M. Franzmann, Gaia Pigino, Simon Alberti

Publikováno v: Biology Open, Vol 9, Iss 7 (2020)

Cells exposed to starvation have to adjust their metabolism to conserve energy and protect themselves. Protein synthesis is one of the major energy-consuming processes and as such has to be tightly controlled. Many mechanistic details about how starv

Externí odkaz: https://doaj.org/article/543e78a5e6734f56ba49cea01d3e5af0

A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia

Autor: Narcis Adrian Petriman, Pleasantine Mill, Margaret A. Keighren, Petra Kiesel, Tooba Quidwai, Jonathan N. Wells, Jiaolong Wang, Laura C. Murphy, Weihua Leng, Esben Lorentzen, Gaia Pigino, Joseph A. Marsh, Emma Hall

Publikováno v: Quidwai, T, Wang, J, Hall, E A, Petriman, N A, Leng, W, Kiesel, P, Wells, J N, Murphy, L C, Keighren, M A, A Marsh, J, Lorentzen, E, Pigino, G & Mill, P 2021, ' A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia ', eLife, vol. 10, e69786 . https://doi.org/10.7554/eLife.69786
eLife
eLife, Vol 10 (2021)
Quidwai, T, Wang, J, Hall, E A, Petriman, N A, Leng, W, Kiesel, P, Wells, J N, Murphy, L C, Keighren, M A, A Marsh, J, Lorentzen, E, Pigino, G & Mill, P 2021, ' A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia ', eLIFE, vol. 10 . https://doi.org/10.7554/eLife.69786

Intraflagellar transport (IFT) is a highly conserved mechanism for motor-driven transport of cargo within cilia, but how this cargo is selectively transported to cilia is unclear. WDR35/IFT121 is a component of the IFT-A complex best known for its ro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f64150e8e37334c7485a5f3df509bf
https://pure.au.dk/portal/da/publications/a-wdr35dependent-coat-protein-complex-transports-ciliary-membrane-cargo-vesicles-to-cilia(26b12d5e-fddf-47db-b664-49374d435eed).html

A local insulin reservoir ensures developmental progression in condition of nutrient shortage in Drosophila

Autor: Suhrid Ghosh, Weihua Leng, Michaela Wilsch-Bräuninger, Suzanne Eaton, Pierre Leopold

SummaryInsulin/IGF signalling (IIS) controls many aspects of development and physiology. In Drosophila, a conserved family of insulin-like peptides (Ilp) is produced by brain neurosecretory cells and exerts systemic functions. Here, we describe the l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2124d306fa4714ade426d580f67a87b7
https://doi.org/10.1101/2021.07.05.451134

A WDR35-dependent coatomer transports ciliary membrane proteins from the Golgi to the cilia

Autor: Pleasantine Mill, Gaia Pigino, Margaret A. Keighren, Joseph A. Marsh, Emma Hall, Laura C. Murphy, Tooba Quidwai, Weihua Leng, Jonathan N. Wells, Petra Kiesel

Intraflagellar transport (IFT) is a highly conserved mechanism for motor-driven transport of cargo within cilia, but how this cargo is selectively transported to cilia and across the diffusion barrier is unclear. WDR35/IFT121 is a component of the IF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4beb679374ed02f0261af67b857cee38
https://doi.org/10.1101/2020.12.22.423978