Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Weidong Gan"'
Autor:
Yi Chen, Yanwen Lu, Lei Yang, Wenliang Ma, Yuhan Dong, Shuoming Zhou, Ning Liu, Weidong Gan, Dongmei Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background NONO-TFE3 rearranged renal cell carcinoma (NONO-TFE3 rRCC) is one of a subtype of TFE3 rRCCs with high malignancy and poor prognosis. Compared with clear cell RCC, NONO-TFE3 rRCC shows a preference for mitochondrial respiration. W
Externí odkaz:
https://doaj.org/article/593e261d924c4c0e858d664cead23d59
Autor:
Yanwen Lu, Yiqi Zhu, Wenliang Ma, Ning Liu, Xiang Dong, Qiancheng Shi, Fei Yu, Hongqian Guo, Dongmei Li, Weidong Gan
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Based on the epidemiological characteristics of susceptibility and age selectivity for women in Xp11.2 translocation renal cell carcinoma (Xp11.2 tRCC), we inferred that estrogen was to be blamed. Rad54 like 2 (Rad54l2) which might be one of
Externí odkaz:
https://doaj.org/article/f3efcb5db0554c87a3524e1929e3320b
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Immunogenic cell death (ICD) is the trigger of adaptive immune responses. However, the role of ICD-related genes in clear cell renal carcinoma (ccRCC) remains unclear. We aimed to identify biomarkers associated with ICD and develop an ICD-re
Externí odkaz:
https://doaj.org/article/93a9fb27c36d46a49940601b97aad273
Autor:
Yang Yang, Haixiang Qin, Meng Ding, Changwei Ji, Wei Chen, Wenli Diao, Haoli Yin, Mengxia Chen, Weidong Gan, Hongqian Guo
Publikováno v:
FEBS Open Bio, Vol 13, Iss 2, Pp 257-269 (2023)
Docetaxel (DTX) plays an important role in treating advanced prostate cancer (PCa). However, nearly all patients receiving DTX therapy ultimately progress to DTX resistance. How to address DTX resistance in PCa remains a key challenge for all urologi
Externí odkaz:
https://doaj.org/article/2bf743effc7d4531a4036adbd1e706b9
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
TFE3-rearranged renal cell carcinoma (RCC) is a rare subtype of renal tumor that primarily affects young women and is characterized by early metastasis and a poor prognosis. This case study presents a 29-year-old woman diagnosed with TFE3-rearranged
Externí odkaz:
https://doaj.org/article/29b0021776d04bbaa889c1cb28f785d6
Publikováno v:
Cancer Medicine, Vol 12, Iss 2, Pp 1260-1268 (2023)
Abstract Background The aim of this study was to investigate the peritumoral pseudocapsule (PC) status and identify the factors influencing PC status in small renal cell carcinoma (RCCs). Methods A total of 147 patients with small RCC (≤4 cm) who h
Externí odkaz:
https://doaj.org/article/023107797bba4f53a3251631e980376a
Autor:
Wenliang Ma, Xin Li, Lei Yang, Jun Pan, Yi Chen, Yanwen Lu, Xiang Dong, Dongmei Li, Weidong Gan
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Clear cell renal cell carcinoma (ccRCC), the most common urological malignancy, has an unfavorable prognosis and an unknown mechanism of progression. Through survival analyses screening of The Cancer Genome Atlas (TCGA) dataset, w
Externí odkaz:
https://doaj.org/article/3b357ea8fdbe4347be8de431eecc8905
Autor:
Lei Yang, Haoli Yin, Yi Chen, Chun Pan, Hexing Hang, Yanwen Lu, Wenliang Ma, Xin Li, Weidong Gan, Hongqian Guo, Dongmei Li
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-16 (2022)
Abstract Background Pseudogenes play an essential role in tumor occurrence and progression. However, the functions and mechanisms of pseudogenes in clear cell renal cell carcinoma (ccRCC) remain largely elusive. Methods We quantified PEBP1P2 expressi
Externí odkaz:
https://doaj.org/article/a9a9f069baba4769abcca3eb2c72c41a
Publikováno v:
Biomarker Research, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Background In our previous study, we found that lncRNA TRAF3IP2 antisense RNA 1 (TRAF3IP2-AS1) could play a critical role in the progression of NONO-TFE3 translocation renal cell carcinoma (NONO-TFE3 tRCC). However, the function of TRAF3IP2
Externí odkaz:
https://doaj.org/article/d45cdf995af4443e9c61a1068803c242
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundXp11.2 translocation renal cell carcinoma (Xp11.2 tRCC) is a group of rare and highly heterogeneous renal cell carcinoma (RCC). The translocation involving TFE3 and different fusion partners lead to overexpression of the chimeric protein. T
Externí odkaz:
https://doaj.org/article/68eea2b228694689a0b9627967c96624