Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Weiding Wu"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 3634-3650 (2024)
Gemcitabine is a standard first-line drug for pancreatic cancer chemotherapy. Nevertheless, gemcitabine resistance is common and significantly limits its therapeutic efficacy, impeding advancements in pancreatic cancer treatment. In this study, throu
Externí odkaz:
https://doaj.org/article/977c18f132574aa0a690046006ab5d02
Autor:
Saimeng Shi, Duancheng Guo, Longyun Ye, Tianjiao Li, Qinglin Fei, Mengxiong Lin, Xianjun Yu, Kaizhou Jin, Weiding Wu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-18 (2023)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant digestive tract tumor with limited clinical treatments. Transforming acidic coiled-coil-containing protein 3 (TACC3) is a component of the centrosome axis and a member of the TACC
Externí odkaz:
https://doaj.org/article/9a85e684f5cb4e558f07329aad902170
Autor:
Chen Liu, Shengming Deng, Zhiwen Xiao, Renquan Lu, He Cheng, Jingjing Feng, Xuxia Shen, Quanxing Ni, Weiding Wu, Xianjun Yu, Guopei Luo
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Background Carbohydrate antigen 19–9 (CA19-9) is the most widely used biomarker for pancreatic cancer. Since CA19-9 closely correlates with patient outcome and tumor stage in pancreatic cancer, the deciphering of CA19-9 biosynthesis provid
Externí odkaz:
https://doaj.org/article/5eaa316c0eed46148d8c9aa04d2bb666
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pancreatic cancer has an exclusive inhibitory tumor microenvironment characterized by a dense mechanical barrier, profound infiltration of immunosuppressive cells, and a lack of penetration of effector T cells, which constitute an important cause for
Externí odkaz:
https://doaj.org/article/a974b5823063411a86e9c2da995ff961
Publikováno v:
Journal of Minimal Access Surgery, Vol 18, Iss 4, Pp 632-634 (2022)
Duodenum-preserving pancreatic head resection (DPPHR) is very complicated due to its difficulty to find the lower common bile duct (CBD), and to preserve the blood supply of the duodenum and CBD. Recently, indocyanine green (ICG) has been widely appl
Externí odkaz:
https://doaj.org/article/3bf3a9962e9144bba6163ff9057d0654
Autor:
Longyun Ye, Kaizhou Jin, Zhenyu Liao, Zhiwen Xiao, Huaxiang Xu, Xuan Lin, Hao Li, Tianjiao Li, Wuhu Zhang, Xuan Han, Wenquan Wang, Heli Gao, Liang Liu, Weiding Wu, Xianjun Yu
Publikováno v:
EBioMedicine, Vol 79, Iss , Pp 104016- (2022)
Summary: Background: Previously, we uncovered a patient subgroup with highly malignant pancreatic cancer with serum markers CEA+/CA125+/CA19-9 ≥ 1000 U/mL (triple-positive, TP). However, the underlying immunosuppressive mechanism in the tumor immun
Externí odkaz:
https://doaj.org/article/5ac80511a6ba49eda212ca5b9c13eb6d
Autor:
Yitao Gong, Yunzhen Qian, Guopei Luo, Yu Liu, Ruijie Wang, Shengming Deng, He Cheng, Kaizhou Jin, Quanxing Ni, Xianjun Yu, Weiding Wu, Chen Liu
Publikováno v:
World Journal of Surgical Oncology, Vol 19, Iss 1, Pp 1-8 (2021)
Abstract Background Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first rate-limiting enzyme of the hexosamine biosynthesis pathway (HBP), which plays a pivotal role in the progression of pancreatic ductal adenocarcinoma (PDAC). Theref
Externí odkaz:
https://doaj.org/article/97b2d54f28c84ea58371efd07c86e3b6
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3748 (2022)
Common pancreatic diseases have caused significant economic and social burdens worldwide. The interstitial microenvironment is involved in and plays a crucial part in the occurrence and progression of pancreatic diseases. Innate lymphoid cells (ILCs)
Externí odkaz:
https://doaj.org/article/3150ed1137c74aa6a98124256454059e
Autor:
Qinglin Fei, Kaizhou Jin, Saimeng Shi, Tianjiao Li, Duancheng Guo, Mengxiong Lin, Xianjun Yu, Weiding Wu, Longyun Ye
Publikováno v:
Acta Biochimica et Biophysica Sinica; Apr2024, Vol. 56 Issue 4, p513-524, 12p
Autor:
Zhenyu Liao, Longyun Ye, Tianjiao Li, Xing Jin, Xuan Lin, Qinglin Fei, Huiru Zhang, Saimeng Shi, Xianjun Yu, Kaizhou Jin, Weiding Wu
Publikováno v:
International Journal of Cancer. 152:2396-2409