Regulation of Burkholderia cenocepacia biofilm formation by RpoN and the c-di-GMP effector BerB.

Autor: Fazli M; Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.; Costerton Biofilm Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rybtke M; Costerton Biofilm Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Steiner E; Department of Plant and Microbial Biology, University of Zurich, Zurich, Switzerland., Weidel E; Department of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland, Saarbrücken, Germany., Berthelsen J; Costerton Biofilm Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groizeleau J; Costerton Biofilm Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bin W; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Zhi BZ; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Yaming Z; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Kaever V; Research Core Unit Metabolomics, Institute of Pharmacology, Hannover Medical School, Hannover, Germany., Givskov M; Costerton Biofilm Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Singapore Centre on Environmental Life Sciences Engineering, Nanyang Technological University, Singapore, Singapore., Hartmann RW; Department of Drug Design and Optimization, Helmholtz Institute for Pharmaceutical Research Saarland, Saarbrücken, Germany., Eberl L; Department of Plant and Microbial Biology, University of Zurich, Zurich, Switzerland., Tolker-Nielsen T; Costerton Biofilm Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: MicrobiologyOpen [Microbiologyopen] 2017 Aug; Vol. 6 (4). Date of Electronic Publication: 2017 Apr 16.

Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.

Autor: Zender M; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Department Drug Design and Optimization, Campus E8.1, 66123 Saarbrücken, Germany., Witzgall F; Helmholtz Centre for Infection Research , Department Structure and Function of Proteins, Inhoffenstrasse 7, 38124 Braunschweig, Germany., Drees SL; Institute of Molecular Microbiology and Biotechnology, University of Münster , Corrensstrasse 3, 48149 Münster, Germany., Weidel E; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Department Drug Design and Optimization, Campus E8.1, 66123 Saarbrücken, Germany., Maurer CK; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Department Drug Design and Optimization, Campus E8.1, 66123 Saarbrücken, Germany., Fetzner S; Institute of Molecular Microbiology and Biotechnology, University of Münster , Corrensstrasse 3, 48149 Münster, Germany., Blankenfeldt W; Helmholtz Centre for Infection Research , Department Structure and Function of Proteins, Inhoffenstrasse 7, 38124 Braunschweig, Germany.; Institut für Biochemie, Biotechnologie und Bioinformatik, Technische Universität Braunschweig , Spielmannstr. 7, 38106 Braunschweig, Germany., Empting M; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Department Drug Design and Optimization, Campus E8.1, 66123 Saarbrücken, Germany., Hartmann RW; Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) , Department Drug Design and Optimization, Campus E8.1, 66123 Saarbrücken, Germany.; Pharmaceutical and Medicinal Chemistry, Department of Pharmacy, Saarland University , Campus E8.1, 66123 Saarbrücken, Germany.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2016 Jun 17; Vol. 11 (6), pp. 1755-63. Date of Electronic Publication: 2016 Apr 28.

Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa.

Autor: Sahner JH; Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Department of Drug Design and Optimization, Campus C2 3, 66123 Saarbrücken, Germany., Empting M; Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Department of Drug Design and Optimization, Campus C2 3, 66123 Saarbrücken, Germany., Kamal A; Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Department of Drug Design and Optimization, Campus C2 3, 66123 Saarbrücken, Germany., Weidel E; Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Department of Drug Design and Optimization, Campus C2 3, 66123 Saarbrücken, Germany., Groh M; Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Department of Drug Design and Optimization, Campus C2 3, 66123 Saarbrücken, Germany., Börger C; PharmBioTec GmbH, Science Park 1, 66123 Saarbrücken, Germany., Hartmann RW; Pharmaceutical and Medicinal Chemistry, Saarland University & Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Department of Drug Design and Optimization, Campus C2 3, 66123 Saarbrücken, Germany. Electronic address: rolf.hartmann@helmholtz-hzi.de.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2015; Vol. 96, pp. 14-21. Date of Electronic Publication: 2015 Apr 06.

Direct rotation-rate detection with a fibre-optic gyro by using digital data processing.

Autor: Böhm, K., Marten, P., Weidel, E., Petermann, K.

Publikováno v: Electronics Letters (Institution of Engineering & Technology); 11/10/1983, Vol. 19 Issue 23, p997-999, 3p

Composing compound libraries for hit discovery--rationality-driven preselection or random choice by structural diversity?

Autor: Weidel E; Department Drug Design & Optimization, Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS), Campus C2.3, 66123 Saarbrücken, Germany., Negri M, Empting M, Hinsberger S, Hartmann RW

Publikováno v: Future medicinal chemistry [Future Med Chem] 2014; Vol. 6 (18), pp. 2057-72.