Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Weichuan Luo"'
Autor:
Fenghua Zhang, Bo Huang, Sagar M. Utturkar, Weichuan Luo, Gregory Cresswell, Seth A. Herr, Suilan Zheng, John V. Napoleon, Rina Jiang, Boning Zhang, Muyi Liu, Nadia Lanman, Madduri Srinivasarao, Timothy L. Ratliff, Philip S. Low
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Folate receptors can perform folate transport, cell adhesion, and/or transcription factor functions. The beta isoform of the folate receptor (FRβ) has attracted considerable attention as a biomarker for immunosuppressive macrophages and myeloid-deri
Externí odkaz:
https://doaj.org/article/6dc8dbece4744d66b4109cdad3fb1700
Autor:
Yun Chang, Gyuhyung Jin, Weichuan Luo, Qian Luo, Juhyung Jung, Sydney N. Hummel, Sandra Torregrosa-Allen, Bennett D. Elzey, Philip S. Low, Xiaojun Lance Lian, Xiaoping Bao
Publikováno v:
Bioactive Materials, Vol 27, Iss , Pp 168-180 (2023)
Adoptive chimeric antigen receptor (CAR)-engineered natural killer (NK) cells have shown promise in treating various cancers. However, limited immunological memory and access to sufficient numbers of allogenic donor cells have hindered their broader
Externí odkaz:
https://doaj.org/article/132da242ecf24ecdaf6268b9a29f76ac
Autor:
Mark Cobbold, Gordon Moody, Kelly McGlinchey, Emily Bosco, Peter Zanvit, Christine Fazenbaker, Weichuan Luo, Jessica Pezold, Clare Hoover
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e5e673da0a984d5aafd7bab7e39bcc6a
Autor:
Peter Zanvit, Dewald van Dyk, Christine Fazenbaker, Kelly McGlinchey, Weichuan Luo, Jessica M. Pezold, John Meekin, Chien-ying Chang, Rosa A. Carrasco, Shannon Breen, Crystal Sao-Fong Cheung, Ariel Endlich-Frazier, Benjamin Clark, Nina J. Chu, Alessio Vantellini, Philip L. Martin, Clare E. Hoover, Kenesha Riley, Steve M. Sweet, David Chain, Yeoun Jin Kim, Eric Tu, Nathalie Harder, Sandrina Phipps, Melissa Damschroder, Ryan N. Gilbreth, Mark Cobbold, Gordon Moody, Emily E. Bosco
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
Prostate cancer is generally considered an immunologically “cold” tumor type that is insensitive to immunotherapy. Targeting surface antigens on tumors through cellular therapy can induce a potent antitumor immune response to “heat up” the tu
Externí odkaz:
https://doaj.org/article/e772d4b790a848fcb94aa4259efad645
Autor:
Weichuan Luo, John V. Napoleon, Fenghua Zhang, Yong Gu Lee, Bingbing Wang, Karson S. Putt, Philip S. Low
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Although CAR T cell therapies have proven to be effective in treating hematopoietic cancers, their abilities to regress solid tumors have been less encouraging. Mechanisms to explain these disparities have focused primarily on differences in cancer c
Externí odkaz:
https://doaj.org/article/ee38390f311143a2964ec9990eb61239
Autor:
Yong Gu Lee, Imrul Shahriar, Philip S. Low, Boning Zhang, Madduri Srinivasarao, Xin Liu, Weichuan Luo
Publikováno v:
Bioconjugate Chemistry. 32:1548-1553
The last step in influenza virus replication involves the assembly of viral components on the infected cell's plasma membrane followed by budding of intact virus from the host cell surface. Because viral neuraminidase and hemagglutinin are both inser
Publikováno v:
Molecular and Clinical Oncology. 17
Chimeric antigen receptors (CARs) recently gained momentum in cancer treatment due to their ability to promote T-cell mediated responses to a specific tumor-associated antigen. CARs are part of the adoptive cell transfer (ACT) strategies that utilize
Autor:
Dewald van Dyk, Peter Zanvit, Christine Fazenbaker, Kelly McGlinchey, Weichuan Luo, Jessica Pezold, John Meekin, Chien-ying Chang, Benjamin Clark, Philip L. Martin, Clare Hoover, Eric Tu, Ryan Gilbreth, Mark Cobbold, Gordon Moody, Emily E. Bosco
Publikováno v:
Cancer Research. 83:LB085-LB085
Prostate cancer is traditionally considered an immunologically “cold” tumor type rendering patients insensitive to immunotherapy. Targeting surface antigens on tumors through cellular therapy can induce a potent anti tumor immune response to “h
Publikováno v:
SSRN Electronic Journal.
The last step in influenza virus replication involves the assembly of viral components on the infected cell’s plasma membrane followed by budding of intact virus from the host cell surface. Because viral neuraminidase and hemagglutinin are both ins
Publikováno v:
Cancer Research. 81:2782-2782
Although CAR T therapies have proven effective in treating liquid cancers, similar CAR T cell therapies have been unsuccessful in treating solid tumors, in part due to their immunosuppressive tumor microenvironments (TMEs). Critical to the establishm