NCX1 represents an ionic Na+ sensing mechanism in macrophages

Autor: Oliver, Paula M., Neubert, Patrick, Homann, Arne, Wendelborn, David, Bär, Anna-Lorena, Krampert, Luka, Trum, Maximilian, Schröder, Agnes, Ebner, Stefan, Weichselbaum, Andrea, Schatz, Valentin, Linz, Peter, Veelken, Roland, Schulte-Schrepping, Jonas, Aschenbrenner, Anna C., Quast, Thomas, Kurts, Christian, Geisberger, Sabrina, Kunzelmann, Karl, Hammer, Karin, Binger, Katrina J., Titze, Jens, Müller, Dominik N., Kolanus, Waldemar, Schultze, Joachim L., Wagner, Stefan, Jantsch, Jonathan

Inflammation and infection can trigger local tissue Na(+)accumulation. This Na+-rich environment boosts proinflammatory activation of monocyte/macrophage-like cells (M phi s) and their antimicrobial activity. Enhanced Na+-driven M phi function requir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a24370931dd8498b16e92bff0ffa79

NCX1 represents an ionic Na⁺ sensing mechanism in macrophages.

Autor: Neubert, Patrick, Homann, Arne, Wendelborn, David, Bär, Anna-Lorena, Krampert, Luka, Trum, Maximilian, Schröder, Agnes, Ebner, Stefan, Weichselbaum, Andrea, Schatz, Valentin, Linz, Peter, Veelken, Roland, Schulte-Schrepping, Jonas, Aschenbrenner, Anna C., Quast, Thomas, Kurts, Christian, Geisberger, Sabrina, Kunzelmann, Karl, Hammer, Karin, Binger, Katrina J.

Publikováno v: PLoS Biology; 6/22/2020, Vol. 18 Issue 6, p1-21, 21p, 2 Diagrams, 8 Graphs

Nanoscale Quantum Dynamics and Electrostatic Coupling

Autor: Weichselbaum, Andreas

Physical nanoscale systems have been analyzed both from an electrostatic point of view and quantum mechanically with respect to quantum computation. We introduce an elaborate code for the efficient numerical simulation of nanoscale electrostatics via

Externí odkaz: http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1091115085

NCX1 represents an ionic Na+ sensing mechanism in macrophages.

Autor: Neubert P; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Homann A; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Wendelborn D; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Bär AL; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Krampert L; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Trum M; Department of Internal Medicine II, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Schröder A; Institute of Orthodontics, University Hospital of Regensburg, Regensburg, Germany., Ebner S; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.; Max Planck Institute of Biochemistry, Martinsried, Germany., Weichselbaum A; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Schatz V; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Linz P; Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Veelken R; Department of Internal Medicine 4, University Hospital Erlangen, Erlangen, Germany., Schulte-Schrepping J; Department for Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Aschenbrenner AC; Department for Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, the Netherlands., Quast T; Molecular Immunology and Cell Biology LIMES Institute, University of Bonn, Bonn, Germany., Kurts C; Institute of Experimental Immunology, University of Bonn, Bonn, Germany., Geisberger S; Experimental and Clinical Research Center (ECRC), a cooperation of Charité-Universitätsmedizin Berlin and Max Delbruck Center for Molecular Medicine, Berlin, Germany.; Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Kunzelmann K; Institute of Physiology, University of Regensburg, Regensburg, Germany., Hammer K; Department of Internal Medicine II, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Binger KJ; Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Australia., Titze J; Cardiovascular and Metabolic Disorders, Duke-NUS Medical School, Singapore., Müller DN; Experimental and Clinical Research Center (ECRC), a cooperation of Charité-Universitätsmedizin Berlin and Max Delbruck Center for Molecular Medicine, Berlin, Germany.; Max Delbruck Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Kolanus W; Molecular Immunology and Cell Biology LIMES Institute, University of Bonn, Bonn, Germany., Schultze JL; Department for Genomics and Immunoregulation, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; Platform for Single Cell Genomics & Epigenomics at the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn, Bonn, Germany., Wagner S; Department of Internal Medicine II, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany., Jantsch J; Institute of Clinical Microbiology and Hygiene, University Hospital of Regensburg and University of Regensburg, Regensburg, Germany.

Publikováno v: PLoS biology [PLoS Biol] 2020 Jun 22; Vol. 18 (6), pp. e3000722. Date of Electronic Publication: 2020 Jun 22 (Print Publication: 2020).