Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Weibin, Zha"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Depression and use of antidepressant medications are both associated with increased risk of obesity, potentially attributed to a reduced serotonin transporter (SERT) function. However, how SERT deficiency promotes obesity is unknown. Here, w
Externí odkaz:
https://doaj.org/article/76530317f3e348398465b60bfd95a71c
Publikováno v:
Mol Pharmacol
Formed by the choroid plexus epithelial (CPE) cells, the blood-cerebrospinal fluid barrier (BCSFB) plays an active role in removing drugs, toxins, and metabolic wastes from the brain. Several organic cation and anion transporters are expressed in the
Autor:
Weibin Zha, Matthew L. Edin, Kimberly C. Vendrov, Robert N. Schuck, Fred B. Lih, Jawahar Lal Jat, J. Alyce Bradbury, Laura M. DeGraff, Kunjie Hua, Kenneth B. Tomer, John R. Falck, Darryl C. Zeldin, Craig R. Lee
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 2124-2136 (2014)
Adipogenesis plays a critical role in the initiation and progression of obesity. Although cytochrome P450 (CYP)-derived epoxyeicosatrienoic acids (EETs) have emerged as a potential therapeutic target for cardiometabolic disease, the functional contri
Externí odkaz:
https://doaj.org/article/b28891d15da546688f2635126a06d9ed
Autor:
Risheng Cao, Zhumei Xu Cronk, Weibin Zha, Lixin Sun, Xuan Wang, Youwen Fang, Elaine Studer, Huiping Zhou, William M. Pandak, Paul Dent, Gregorio Gil, Phillip B. Hylemon
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 8, Pp 2234-2244 (2010)
Bile acids are important regulatory molecules that can activate specific nuclear receptors and cell signaling pathways in the liver and gastrointestinal tract. In the current study, the chronic bile fistula (CBF) rat model and primary rat hepatocytes
Externí odkaz:
https://doaj.org/article/dc92c16a4c334b9aa4faf848b25d30bb
Autor:
Yan Liu, Jingwei Zhang, Fei Qian, Kun Hao, Fang Zhou, Yao-yao Wang, Xiao-yang Chen, Weibin Zha, Guangji Wang, Yuan Sun
Publikováno v:
Acta Pharmacol Sin
Intracellular Staphylococcus aureus (S. aureus) often causes clinical failure and relapse after antibiotic treatment. We previously found that 20(S)-ginsenoside Rh2 [20(S)-Rh2] enhanced the therapeutic effect of quinolones in a mouse model of periton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2489c293417795d38c25686c1b41da4a
https://europepmc.org/articles/PMC8564512/
https://europepmc.org/articles/PMC8564512/
Autor:
Ying, Zhang, Jiye, A, Wang, Guangji, Qing, Huang, Bei, Yan, Weibin, Zha, Shenghua, Gu, Linsheng, Liu, Hongcan, Ren, Meiting, Ren, Longsheng, Sheng
Publikováno v:
In Journal of Chromatography B 2009 877(18):1751-1757
Autor:
Robert N Schuck, Weibin Zha, Matthew L Edin, Artiom Gruzdev, Kimberly C Vendrov, Tricia M Miller, Zhenghong Xu, Fred B Lih, Laura M DeGraff, Kenneth B Tomer, H Michael Jones, Liza Makowski, Leaf Huang, Samuel M Poloyac, Darryl C Zeldin, Craig R Lee
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110162 (2014)
Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its progression. Cytochrome P450 (CYP) epoxygenases metabolize arachidonic acid to biologically act
Externí odkaz:
https://doaj.org/article/29650032df5d48bc836fda83e9a5f696
Autor:
Beth S Zha, Xiaoshan Wan, Xiaoxuan Zhang, Weibin Zha, Jun Zhou, Martin Wabitsch, Guangji Wang, Vijay Lyall, Phillip B Hylemon, Huiping Zhou
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59514 (2013)
BackgroundHIV protease inhibitors (PI) are core components of Highly Active Antiretroviral Therapy (HAART), the most effective treatment for HIV infection currently available. However, HIV PIs have now been linked to lipodystrophy and dyslipidemia, w
Externí odkaz:
https://doaj.org/article/08dcda328ebf4cc587061c41842f8f92
Autor:
Weibin Zha, Guangji Wang, Weiren Xu, Xuyuan Liu, Yun Wang, Beth S Zha, Jian Shi, Qijin Zhao, Phillip M Gerk, Elaine Studer, Phillip B Hylemon, William M Pandak, Huiping Zhou
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54349 (2013)
BackgroundHIV protease inhibitor (PI)-induced inflammatory response in macrophages is a major risk factor for cardiovascular diseases. We have previously reported that berberine (BBR), a traditional herbal medicine, prevents HIV PI-induced inflammato
Externí odkaz:
https://doaj.org/article/48ba76f137a34e8ab09360090c8231ae
Autor:
Weibin Zha, Guang Liang, Jian Xiao, Elaine J Studer, Phillip B Hylemon, William M Pandak, Guangji Wang, Xiaokun Li, Huiping Zhou
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9069 (2010)
HIV protease inhibitor (PI)-induced inflammatory response plays an important role in HIV PI-associated dyslipidemia and cardiovascular complications. This study examined the effect of berberine, a traditional herb medicine, on HIV PI-induced inflamma
Externí odkaz:
https://doaj.org/article/562d5ee929464bc2a1c8cf80b57858de