Zobrazeno 1 - 10
of 30
pro vyhledávání: '"WeiDong Leng"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Background The vast majority of lncRNAs have low expression abundance, which greatly limits their functional range and impact. As a high expression abundance lncRNA, FGD5-AS1’s non-ceRNA biological function in cancer is unclear. Methods RN
Externí odkaz:
https://doaj.org/article/bb27a4b300324a6ea2ad226e148f8638
Autor:
Shanshan Qin, Qiwei Guo, Yue Liu, Xiangang Zhang, Pan Huang, Hedong Yu, Lingyun Xia, Weidong Leng, Dandan Li
Publikováno v:
Cell Death and Disease, Vol 15, Iss 5, Pp 1-14 (2024)
Abstract Transforming growth factor beta (TGFβ) signaling plays a critical role in tumorigenesis and metastasis. However, little is known about the biological function of TGFbeta-induced lncRNA in cancer. In this study, we discovered a novel TGFbeta
Externí odkaz:
https://doaj.org/article/a3bfbb55d39c44d1a771cd16999ff85b
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
PurposeThe primary cause of pulp and periapical diseases is the invasion of bacteria into the root canal, which results from the continuous destruction of dental hard tissues. Effective management of infections during root canal therapy necessitates
Externí odkaz:
https://doaj.org/article/05342425b3f74a15b2506813ad292958
Publikováno v:
BMC Oral Health, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Purpose To characterize the bacterial community in the primarily infected root canals. Methods A total of 13 samples were collected from the primarily infected root canals. 16 S rDNA sequencing was performed to define bacterial community. Ta
Externí odkaz:
https://doaj.org/article/a37e8cce53b84fafbd6fe3d385819a11
Autor:
Dandan Li, Lingyun Xia, Pan Huang, Zidi Wang, Qiwei Guo, Congcong Huang, Weidong Leng, Shanshan Qin
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Background Cancer/testis (CT) antigens/genes are usually overexpressed in cancers and exhibit high immunogenicity, making them promising targets for immunotherapy and cancer vaccines. The role of serine protease PRSS56 in cancers remains unk
Externí odkaz:
https://doaj.org/article/c58fed009fe043bfbeda73a254e904fa
Autor:
Lingyun Xia, Tianshu Zhang, Juncheng Yao, Kaitian Lu, Ziqiu Hu, Xinsheng Gu, Yongji Chen, Shanshan Qin, Weidong Leng
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108201- (2023)
Summary: Accumulating evidence has shown that fibromodulin (FMOD) plays a pivotal role in tumorigenesis and metastasis. However, the biological function of FMOD in oral squamous cell carcinoma (OSCC) remains largely unclear to date. In this study, we
Externí odkaz:
https://doaj.org/article/6511fbecd68143339d19fcdfbe1408bd
Autor:
Dandan Li, Lingyun Xia, Pan Huang, Zidi Wang, Qiwei Guo, Congcong Huang, Weidong Leng, Shanshan Qin
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract We previously reported that IGFBP7 plays a role in maintaining mRNA stability of oncogenic lncRNA UBE2CP3 by RNA-RNA interaction in gastric cancer (GC). Clinical cohort studies had implied an oncogenic role of IGFBP7 in GC. However, the mole
Externí odkaz:
https://doaj.org/article/7bba011b48154c71909c6b54aac8048a
Autor:
Pan Huang, Lingyun Xia, Qiwei Guo, Congcong Huang, Zidi Wang, Yinxuan Huang, Shanshan Qin, Weidong Leng, Dandan Li
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundThe dysregulated genes and miRNAs in tumor progression can be used as biomarkers for tumor diagnosis and prognosis. However, the biomarkers for predicting the clinical outcome of gastrointestinal cancer (GIC) are still scarce.MethodsGenome-
Externí odkaz:
https://doaj.org/article/dbe09ca2bde6431abd940900abfb28cd
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
Abstract Background Recently, convalescent plasma (CP) transfusion was employed for severe or critically ill patients with coronavirus disease-2019. However, the benefits of CP for patients with different conditions are still in debate. To contribute
Externí odkaz:
https://doaj.org/article/84df30aea4a14031aa56ed251dc69376
Autor:
Hedong Yu, Lingyun Xia, Xieyuan Leng, Yongji Chen, Li Zhang, Xiaobing Ni, Jie Luo, Weidong Leng
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Endothelial progenitor cells (EPCs) expressing vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) and bone marrow mesenchymal stem cells (BMSCs) expressing endogenous bone morphogenetic protein-2 (BMP-2) play the impo
Externí odkaz:
https://doaj.org/article/e28e1029fc6c4ce0b53d4991fb5057c0