Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Wei-xiao Niu"'
Publikováno v:
Phytotherapy Research.
Publikováno v:
Acta Pharmacol Sin
Liver fibrosis is one of the most severe pathologic consequences of chronic liver diseases, and effective therapeutic strategies are urgently needed. Proton pump inhibitors (PPIs) are H + /K + -ATPase inhibitors and currently used to treat acid-relat
Autor:
Wei-Xiao, Niu, Yun-Yang, Bao, Na, Zhang, Zhen-Ning, Lu, Mao-Xu, Ge, Yi-Ming, Li, Yi, Li, Ming-Hua, Chen, Hong-Wei, He
Publikováno v:
Bioorganic Chemistry. 127:105971
Liver fibrosis is an important process in chronic liver disease and is strongly related to poor prognosis. Dehydromevalonolactone (C8) is a natural product isolated from a fungus of Fusarium sp. CPCC 401218, and its pharmacological activity has never
Autor:
Rong-Guang Shao, Dong-ke Yu, Maoxu Ge, Hong-Tao Liu, Juxian Wang, Wei-xiao Niu, Yi-xuan Zhang, Hongwei He, Shi-Ying Cai, Zhang Na, Ren Jinfeng, Yucheng Wang
Publikováno v:
Acta Pharmacol Sin
The manipulation of bile acid (BA) homeostasis by blocking the ileal apical Na(+)-dependent bile salt transporter (ASBT/SLC10A2) may have therapeutic effects in nonalcoholic fatty liver disease. We developed a novel ASBT inhibitor, an N-(3,4-o-dichlo
Autor:
Dong‐ke Yu, Hong-Tao Liu, Zhen‐ning Lu, Wei-xiao Niu, Ge Maoxu, He Hongwei, Rong-Guang Shao, Bao Yunyang, Na Zhang, Rui Huang
Publikováno v:
Br J Pharmacol
Background and purpose This study investigates the antifibrotic activities and potential mechanisms of costunolide (COS), a natural sesquiterpene compound. Experimental approach Rats subjected to bile duct ligation and mice challenged with CCl4 were
Autor:
Shao Duanyang, Guoning Zhang, Ziqiang Li, Wei-xiao Niu, Mei Zhu, Juxian Wang, Donghui Li, Yucheng Wang
Publikováno v:
Chemistry & Biodiversity. 16
A new series of (sulfonamido)propanamides (6a1-6a13, 6b1-6b15, 7c1-7c5, 6d1-6d5, 6e1-6e6) was designed and synthesized. All the synthesized compounds were characterized by NMR and mass spectrometry. The target compounds were evaluated for their in vi