Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Wei-ling FU"'
Autor:
Jun-Fu Huang, Dong-Zhu Zeng, Guang-Jie Duan, Yan Shi, Guo-Hong Deng, Han Xia, Han-Qing Xu, Na Zhao, Wei-Ling Fu, Qing Huang
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145698 (2015)
The high degree of intra-tumor heterogeneity has meant that it is important to develop sensitive and selective assays to detect low-abundance KRAS mutations in metastatic colorectal carcinoma (mCRC) patients. As a major potential source of tumor DNA
Externí odkaz:
https://doaj.org/article/549c210b3f424fb5b5ad2232a9b665ce
Autor:
Yue-Ping Liu, Hai-Yan Wu, Xiang Yang, Han-Qing Xu, Yong-Chuan Li, Da-Chuan Shi, Jun-Fu Huang, Qing Huang, Wei-Ling Fu
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0121745 (2015)
Thiopurine drugs are well established treatments in the management of inflammatory bowel disease (IBD), but their use is limited by significant adverse drug reactions (ADRs). Thiopurine S-methyltransferase (TPMT) is an important enzyme involved in th
Externí odkaz:
https://doaj.org/article/1912f0afa5294176ad1523b3189781f3
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144234 (2015)
Azathioprine (AZA) is widely used as an immunosuppressive drug in autoimmune diseases, but its use is limited by significant adverse drug reactions (ADRs). Thiopurine S-methyltransferase (TPMT) is an important enzyme involved in AZA metabolism. Sever
Externí odkaz:
https://doaj.org/article/d066015caf1e4b3aa118a732c8167d42
Autor:
Dong Chen, Jun-Fu Huang, Kai Liu, Li-Qun Zhang, Zhao Yang, Zheng-Ran Chuai, Yun-Xia Wang, Da-Chuan Shi, Qing Huang, Wei-Ling Fu
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90607 (2014)
BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease with multiple underlying causative genetic mutations. The B-type Raf proto-oncogene (BRAF) plays an important role in the mitogen-activated protein kinase (MAPK) signaling cascade during
Externí odkaz:
https://doaj.org/article/c34b62c2d2954f9eb137bda523e9b79e
Autor:
Dong Chen, Zhao Yang, Han Xia, Jun-Fu Huang, Yang Zhang, Tian-Nun Jiang, Gui-Yu Wang, Zheng-Ran Chuai, Wei-Ling Fu, Qing Huang
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e91824 (2014)
Genotyping of thiopurine S-methyltransferase (TPMT) is recommended for predicting the adverse drug response of thiopurines. In the current study, a novel version of allele-specific PCR (AS-PCR), termed competitive real-time fluorescent AS-PCR (CRAS-P
Externí odkaz:
https://doaj.org/article/e79cb035336b43cfbb5ed79642eb7b5e
Autor:
Dong Chen, Li-Qun Zhang, Jun-Fu Huang, Kai Liu, Zheng-Ran Chuai, Zhao Yang, Yun-Xia Wang, Da-Chuan Shi, Qian Liu, Qing Huang, Wei-Ling Fu
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e101354 (2014)
BRAF mutations have been well described in non-small cell lung cancer (NSCLC) for several years, but the clinical features of patients harboring BRAF mutations are still not well described. We performed a meta-analysis to identify common clinical fea
Externí odkaz:
https://doaj.org/article/363686d0f6f540d7ba30e81ee197f875
Publikováno v:
Trends in Analytical Chemistry
Trends in Analytical Chemistry, Elsevier, 2018, 105, pp.185-190. ⟨10.1016/j.trac.2018.05.009⟩
Trends in Analytical Chemistry, Elsevier, 2018, 105, pp.185-190. ⟨10.1016/j.trac.2018.05.009⟩
The Surface Enhanced Raman Scattering (SERS) is a powerful method to observe and detect a large panel of molecules. Through the highly enhanced Raman signal, it is possible to identify a very low concentration of molecules and to improve the limit of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c89a5b067ef9f2b555d4996fe86e428
https://hal-univ-lemans.archives-ouvertes.fr/hal-01921330
https://hal-univ-lemans.archives-ouvertes.fr/hal-01921330
Publikováno v:
Medical Journal of Chinese People's Liberation Army, Vol 40, Iss 2, Pp 163-168 (2015)
Warfarin is still the most clinically used oral anti-coagulant despite of its narrow therapeutic index and high risk of hemorrhage. The mean daily dose of warfarin varies widely from patient to patient, and to achieve the same therapeutic effect, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::97e754fe5c37ca4f3fe84b66c5df5820
http://www.plamj.org/index.php/plamj/article/view/1093
http://www.plamj.org/index.php/plamj/article/view/1093
Autor:
Jing Zhu, Xiao-li Zhang, Han Xia, Yong-Biao Zhang, Ming Liu, Hong Pan, Wei-Ling Fu, Feng Zhang, Yang Zhang
Publikováno v:
Oncology Letters
The present study aimed to investigate the molecular basis of lung cancer development using a microarray to identify the differentially-expressed genes associated with the various tumor-node-metastasis (TNM) stages of lung adenocarcinoma. This subtyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfdb3d4037f731b49bbecc65f9cbdc83
https://doi.org/10.3892/ol.2013.1469
https://doi.org/10.3892/ol.2013.1469
Publikováno v:
Bioscience Reports. 30:217-222
Many studies have shown that epigenetic regulation of ERs (oestrogen receptors) plays a key role in the pathogenesis of leukaemia. In the present study, it was found that the methylated status of ERalpha-A might serve as an epigenetic biomarker of le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4e9eb228150d3d98ac36db5e1670b0
https://doi.org/10.1042/bsr20090044
https://doi.org/10.1042/bsr20090044