Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Wei-guang LI"'
Autor:
Chen Huang, Pei-Yi Sun, Yiming Jiang, Yuandong Liu, Zhichao Liu, Shao-Ling Han, Bao-Shan Wang, Yong-Xin Huang, An-Ran Ren, Jian-Fei Lu, Qin Jiang, Ying Li, Michael X. Zhu, Zhirong Yao, Yang Tian, Xin Qi, Wei-Guang Li, Tian-Le Xu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Psoriasis is an immune-mediated skin disease associated with neurogenic inflammation, but the underlying molecular mechanism remains unclear. We demonstrate here that acid-sensing ion channel 3 (ASIC3) exacerbates psoriatic inflammation thro
Externí odkaz:
https://doaj.org/article/6523cda04e994d1faf0dc694d6adbcec
Autor:
Hoiyin Cheung, Tong-Zhou Yu, Xin Yi, Yan-Jiao Wu, Qi Wang, Xue Gu, Miao Xu, Meihua Cai, Wen Wen, Xin-Ni Li, Ying-Xiao Liu, Ying Sun, Jijian Zheng, Tian-Le Xu, Yan Luo, Ma-Zhong Zhang, Wei-Guang Li
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-17 (2024)
Abstract Benzodiazepines, commonly used for anxiolytics, hinder conditioned fear extinction, and the underlying circuit mechanisms are unclear. Utilizing remimazolam, an ultra-short-acting benzodiazepine, here we reveal its impact on the thalamic nuc
Externí odkaz:
https://doaj.org/article/e299587192fe40fabc99a0c7c0d5c10e
Autor:
Yichen Yan, Xiaoli Zheng, Gang Liu, Guocheng Shi, Cong Li, Hongtong Chen, Xiaomin He, Kana Lin, Zhaohui Deng, Hao Zhang, Wei-Guang Li, Huiwen Chen, Xiaoping Tong, Zhongqun Zhu
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109633- (2024)
Summary: Chronic hypoxia, common in neonates, disrupts gut microbiota balance, which is crucial for brain development. This study utilized cyanotic congenital heart disease (CCHD) patients and a neonatal hypoxic rat model to explore the association.
Externí odkaz:
https://doaj.org/article/817bf388ae944f97976d57fafff46693
Autor:
Hao Zhang, Qing-Qi Zhou, He Chen, Xiao-Qing Hu, Wei-Guang Li, Yang Bai, Jun-Xia Han, Yao Wang, Zhen-Hu Liang, Dan Chen, Feng-Yu Cong, Jia-Qing Yan, Xiao-Li Li
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-40 (2023)
Abstract Electroencephalography (EEG) is a non-invasive measurement method for brain activity. Due to its safety, high resolution, and hypersensitivity to dynamic changes in brain neural signals, EEG has aroused much interest in scientific research a
Externí odkaz:
https://doaj.org/article/438acbf2c8974f8ba1584727ccdc5b75
Autor:
Kaixing Zeng, Zhi-Han Jiao, Qin Jiang, Ru He, Yixin Zhang, Wei-Guang Li, Tian-Le Xu, Yiyun Chen
Publikováno v:
ACS Central Science, Vol 10, Iss 1, Pp 163-175 (2023)
Externí odkaz:
https://doaj.org/article/ec69b87abccf4ac0a764c76588246113
Autor:
Wenying Xu, Jie Wang, Xin-Ni Li, Jingxue Liang, Lu Song, Yi Wu, Zhenguo Liu, Bomin Sun, Wei-Guang Li
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-21 (2023)
Abstract Deep brain stimulation (DBS) is a well-established and effective treatment for patients with advanced Parkinson's disease (PD), yet its underlying mechanisms remain enigmatic. Optogenetics, primarily conducted in animal models, provides a un
Externí odkaz:
https://doaj.org/article/0a27b693a449457aba181a7227498f4d
Publikováno v:
工程科学学报, Vol 44, Iss 11, Pp 1897-1908 (2022)
To address the problem of high filling cost in an open pit to an underground mine, based on the machine learning method, the filling cementitious material needed for subsequent backfill mining method was developed using the available industrial waste
Externí odkaz:
https://doaj.org/article/bedc412c5acd488bbc515a32bd793ff8
Autor:
Qi Wang, Jia-Jie Zhu, Lizhao Wang, Yan-Peng Kan, Yan-Mei Liu, Yan-Jiao Wu, Xue Gu, Xin Yi, Ze-Jie Lin, Qin Wang, Jian-Fei Lu, Qin Jiang, Ying Li, Ming-Gang Liu, Nan-Jie Xu, Michael X. Zhu, Lu-Yang Wang, Siyu Zhang, Wei-Guang Li, Tian-Le Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Ensembles of fear and extinction memories compete and interact to drive opposing behaviors. Here the authors identified insular cortical circuits as an executive gateway that decipher between fear and extinction memories via distinct subcortical path
Externí odkaz:
https://doaj.org/article/e273ae91804a40ce9bce87dcd02dd204
Autor:
Yan-Jiao Wu, Xin Yi, Xue Gu, Qi Wang, Qin Jiang, Ying Li, Michael X. Zhu, Jianqing Ding, Wei-Guang Li, Tian-Le Xu
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106322- (2023)
Summary: Homeostatic synaptic scaling entails adjustment of synaptic strength on a cell to prolonged changes of neuronal activity, which is postulated to participate in neuropsychiatric disorders in vivo. Here, we find that sustained elevation in amb
Externí odkaz:
https://doaj.org/article/bd12758baa9a4aaea89350f5d492957a
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/440c186182c047f3a089319615668743