Zobrazeno 1 - 10
of 605
pro vyhledávání: '"Wei-dong Li"'
Autor:
Miaomiao Zhang, Wanyao Wang, Qun Ye, Yun Fu, Xuemin Li, Ke Yang, Fan Gao, An Zhou, Yonghui Wei, Shuang Tian, Shen Li, Fengjiang Wei, Wentao Shi, Wei-Dong Li
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Background Alzheimer’s disease (AD) is a degenerative neurological disorder. Recent studies have indicated that histone deacetylases (HDACs) are among the most prominent epigenetic therapy targets and that HDAC inhibitors have therapeutic
Externí odkaz:
https://doaj.org/article/6a67a3bc131c45e290ffae965c60c35b
Publikováno v:
Metabolites, Vol 14, Iss 11, p 590 (2024)
Background/Objectives: Fritillaria taipaiensis P.Y. Li is a valuable traditional Chinese medicinal herb that utilizes bulbs as medicine, which contain multiple alkaloids. Biomass, as a sustainable resource, has promising applications in energy, envir
Externí odkaz:
https://doaj.org/article/9471e0da63944e9db378d87cfb46a5ee
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Despite aging is closely linked to increased aneuploidy in the oocytes, the mechanism of how aging affects aneuploidy remains largely elusive. Here, we applied single-cell parallel methylation and transcriptome sequencing (scM&T-seq) data fr
Externí odkaz:
https://doaj.org/article/28fdcabdf16840ceaa11e47c379ba8a7
Autor:
Fa-Li Zhang, Wei-Dong Li, Geng Zhang, Min Zhang, Zhao-Jun Liu, Ke-Xin Zhu, Qing-Chun Liu, Shu-Er Zhang, Wei Shen, Xi-Feng Zhang
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Cattle (Bos taurus) are a major large livestock, however, compared with other species, the transcriptional specificity of bovine oocyte development has not been emphasised. Results To reveal the unique transcriptional signatures o
Externí odkaz:
https://doaj.org/article/7e4133dba7204a14ac4824511c5134e9
Autor:
Jinjin Li, Qun Ye, Hongxiao Jiao, Wanyao Wang, Kai Zhang, Chen Chen, Yuan Zhang, Shuzhi Feng, Ximo Wang, Yubao Chen, Huailin Gao, Fengjiang Wei, Wei-Dong Li
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
AimsWe aimed to construct a prediction model of type 2 diabetes mellitus (T2DM) in a Han Chinese cohort using a genetic risk score (GRS) and a nongenetic risk score (NGRS).MethodsA total of 297 Han Chinese subjects who were free from type 2 diabetes
Externí odkaz:
https://doaj.org/article/c7b3681a2e55412d8a280b3fd4d80cf2
Publikováno v:
npj Clean Water, Vol 5, Iss 1, Pp 1-9 (2022)
Abstract Nanofiltration (NF) membranes circumventing global water scarcity with excellent separation and antibacterial performances are highly desirable for efficient water treatment but remain a great challenge. Herein, a nanofiltration membrane was
Externí odkaz:
https://doaj.org/article/67056e98cf374d468118c96acadff5a5
Autor:
Lian-Tao Hu, Wen-Jun Deng, Zhen-Sheng Chu, Luo Sun, Chun-Bin Zhang, Shi-Zhen Lu, Jin-Ru Weng, Qiao-Sheng Ren, Xin-Yu Dong, Wei-Dong Li, Xue-Bin Li, Yun-Ting Du, Yue Li, Wei-Qun Wang
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background The expression profiles and molecular mechanisms of CXC chemokine receptors (CXCRs) in Lung adenocarcinoma (LUAD) have been extensively explored. However, the comprehensive prognostic values of CXCR members in LUAD have not yet be
Externí odkaz:
https://doaj.org/article/d2ec6790745146d79cd48dd37d7273af
Publikováno v:
BMC Psychiatry, Vol 22, Iss 1, Pp 1-6 (2022)
Abstract Background Observational studies suggest that sleep disturbances are commonly associated with schizophrenia. However, it is uncertain whether this relationship is causal. To investigate the bidirectional causal relation between sleep traits
Externí odkaz:
https://doaj.org/article/27bfa9c67df340018ddaa310e25809fe
Autor:
Yuan Zhang, Rongrong Yang, Abigail Dove, Xuerui Li, Hongxi Yang, Shu Li, Ju Wang, Wei-Dong Li, Hongyu Zhao, Weili Xu, Yaogang Wang
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Risk genes linked to the development of gout have been identified, and lifestyle factors are related to gout risk. It remains unclear whether healthy lifestyle factors can mitigate the genetic risk of gout. Therefore, we aimed to
Externí odkaz:
https://doaj.org/article/aa77493be1d44e32894c7cf5351f743f
Autor:
Jing Zhao, Yuan Zhang, Jiali Qiu, Xiaodan Zhang, Fengjiang Wei, Jiayi Feng, Chen Chen, Kai Zhang, Shuzhi Feng, Wei-Dong Li
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Based on the high incidence of chronic kidney disease (CKD) in recent years, a better early prediction model for identifying high-risk individuals before end-stage renal failure (ESRD) occurs is needed. We conducted a nested case–control s
Externí odkaz:
https://doaj.org/article/3c7acecd3d974b279feffc89ae3e3c38