Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Wei-chi Ku"'
Autor:
Ya-Yun Wang, Ying-Hung Lin, Vin-Cent Wu, Yu-Hua Lin, Chia-Yen Huang, Wei-Chi Ku, Chiao-Yin Sun
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1671 (2023)
Oxidative stress is the etiology for 30–80% of male patients affected by infertility, which is a major health problem worldwide. Klotho protein is an aging suppressor that functions as a humoral factor modulating various cellular processes includin
Externí odkaz:
https://doaj.org/article/ab1d39d9dd7b4bf38640e205b9ef5c2e
Autor:
Mong-Liang Lu, Wei-Chi Ku, Nailis Syifa, Shu-Chin Hu, Chia-Te Chou, Yi-Hsio Wu, Po-Hsiu Kuo, Chun-Hsin Chen, Wei J. Chen, Tzu-Hua Wu
Publikováno v:
Nutrients, Vol 14, Iss 16, p 3320 (2022)
Inadequate levels of 5-methyltetrahydrofolate (5-MTHF) and the T variant of MTHFR C677T have been suggested to be associated with an increased risk of developing mental illness, whereas the PON1 SNP variant provides a protective role. However, report
Externí odkaz:
https://doaj.org/article/7b8953e59013429ab83362b9e25a467f
Autor:
Ya-Yun Wang, Chih-Chun Ke, Yen-Lin Chen, Yu-Hua Lin, I-Shing Yu, Wei-Chi Ku, Moira K O'Bryan, Ying-Hung Lin
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1009020 (2020)
Approximately 2-15% of couples experience infertility, and around half of these cases are attributed to male infertility. We previously identified TBC1D21 as a sterility-related RabGAP gene derived from infertile men. However, the in vivo function of
Externí odkaz:
https://doaj.org/article/4514cf1dcbfc404f873607ad90ab8925
Autor:
Yen-Chieh Wang, Wei-Chi Ku, Chih-Yi Liu, Yu-Che Cheng, Chih-Cheng Chien, Kang-Wei Chang, Chi-Jung Huang
Publikováno v:
Diagnostics, Vol 11, Iss 12, p 2270 (2021)
In bladder cancer, urothelial carcinoma is the most common histologic subtype, accounting for more than 90% of cases. Pathogenic effects due to the dysbiosis of gut microbiota are localized not only in the colon, but also in regulating bladder cancer
Externí odkaz:
https://doaj.org/article/1fb17735239c46d3b935abb248217b28
Autor:
Rong-Long Chen, Li-Hua Fang, Xin-Yi Yang, Mohsin El Amrani, Esther Veronique Uijtendaal, Yen-Fu Chen, Wei-Chi Ku
Publikováno v:
Pharmaceuticals, Vol 14, Iss 7, p 613 (2021)
Busulfan has been used as a conditioning regimen in allogeneic hematopoietic cell stem transplantation (HSCT). Owing to a large inter-individual variation in pharmacokinetics, therapeutic drug monitoring (TDM)-guided busulfan dosing is necessary to r
Externí odkaz:
https://doaj.org/article/2abc79dd6f3144afa33fb187d9b0f1a7
Autor:
Wei-Hsiang Hsu, Yuh-Chiang Shen, Young-Ji Shiao, Ching-Hua Kuo, Chung-Kuang Lu, Tai-Yuan Lin, Wei-Chi Ku, Yun-Lian Lin
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0209184 (2019)
Ischemic stroke is one of the most common causes of death worldwide and is a major cause of acquired disability in adults. However, there is still a need for an effective drug for its treatment. Buyang Huanwu decoction (BHD), a traditional Chinese me
Externí odkaz:
https://doaj.org/article/8f371b00a0974025af0d46a5d1ee288c
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 187 (2021)
Kaempferitrin is extracted in significantly high quantities from the leaves of Cinnamomum osmophloeum, which belongs to a group of plant species that comes under the genus Cinnamomum, well-known for its established anti-diabetic property in Chinese m
Externí odkaz:
https://doaj.org/article/00d7a14394b74908a248ac4f1e1723ac
Autor:
Yu-Hua Lin, Chia-Yen Huang, Chih-Chun Ke, Ya-Yun Wang, Tsung-Hsuan Lai, Hsuan-Che Liu, Wei-Chi Ku, Chying-Chyuan Chan, Ying-Hung Lin
Publikováno v:
Biomedicines, Vol 8, Iss 11, p 518 (2020)
Septins (SEPTs) are highly conserved GTP-binding proteins and the fourth component of the cytoskeleton. Polymerized SEPTs participate in the modulation of various cellular processes, such as cytokinesis, cell polarity, and membrane dynamics, through
Externí odkaz:
https://doaj.org/article/7cba0c060a28400c954caf34cf499448
Autor:
Chih-Chun Ke, Ying-Hung Lin, Ya-Yun Wang, Ying-Yu Wu, Mei-Feng Chen, Wei-Chi Ku, Han-Sun Chiang, Tsung-Hsuan Lai
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3292 (2018)
Few papers have focused on small guanosine triphosphate (GTP)-binding proteins and their regulation during spermatogenesis. TBC1D21 genes (also known as male germ cell RAB GTPase-activating protein MGCRABGAP) are related to sterility, as determined t
Externí odkaz:
https://doaj.org/article/528ff41adf4646aeb3a6c4620ca74088
Autor:
Ying-Hung Lin, Chih-Chun Ke, Ya-Yun Wang, Mei-Feng Chen, Tsung-Ming Chen, Wei-Chi Ku, Han-Sun Chiang, Chung-Hsin Yeh
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 1, p 97 (2017)
According to recent estimates, 2%–15% of couples are sterile, and approximately half of the infertility cases are attributed to male reproductive factors. However, the reasons remain undefined in approximately 25% of male infertility cases, and mos
Externí odkaz:
https://doaj.org/article/19a53148c5c74a0fbb31f5d2ed842488