Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Wei-Yong Lin"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Amyotrophic lateral sclerosis (ALS), the most prevalent motor neuron disease characterized by its complex genetic structure, lacks a single diagnostic test capable of providing a conclusive diagnosis. In order to demonstrate the potential fo
Externí odkaz:
https://doaj.org/article/f1814ac5f6c343cab1983ff554f20117
Autor:
Wei-Hsiang Hsu, Chanikan Sangkhathat, Mei-Kuang Lu, Wei-Yong Lin, Hsin-Ping Liu, Yun-Lian Lin
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 603 (2024)
Blue light is the higher-energy region of the visible spectrum. Excessive exposure to blue light is known to induce oxidative stress and is harmful to the eyes. The stems of Dendrobium nobile Lindl. (Orchidaceae), named Jinchaishihu, have long been u
Externí odkaz:
https://doaj.org/article/0a051e1dc5124d92aaaeea8ff52fb274
Autor:
Chien-Yuan Chen, Yung-Mei Chao, Ching-Chang Cho, Cheng-Sheng Chen, Wei-Yong Lin, Yi-Hung Chen, Marlène Cassar, Cecilia S. Lu, Jenq-Lin Yang, Julie Y. H. Chan, Suh-Hang H. Juo
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background We previously reported that miR-195 exerts neuroprotection by inhibiting Sema3A and cerebral miR-195 levels decreased with age, both of which urged us to explore the role of miR-195 and miR-195-regulated Sema3 family members in ag
Externí odkaz:
https://doaj.org/article/84c1bc3705264bf0876a2b3bc94b48f3
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15587 (2023)
LRRK2 mutations are the leading cause of familial Parkinson’s disease (PD) and are a significant risk factor for idiopathic PD cases. However, the molecular mechanisms underlying the degeneration of dopaminergic (DA) neurons in LRRK2 PD patients re
Externí odkaz:
https://doaj.org/article/ab683be58bb140ca81a00c8ad9631df4
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The found in neurons (fne), a paralog of the RNA-binding protein ELAV gene family in Drosophila, is required for post-transcriptional regulation of neuronal development and differentiation. Previous explorations into the functions of the FNE protein
Externí odkaz:
https://doaj.org/article/c4cc57420132403bb3ca1b6ca5da6482
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder causing 70% of dementia cases. However, the mechanism of disease development is still elusive. Despite the availability of a wide range of biological data, a comprehensive understand
Externí odkaz:
https://doaj.org/article/b614a110173d4f4ab37eb591658964f1
Autor:
Chih-Hao Lu, Hao-Teng Chang, Lee-Fen Hsu, Ming-Hsueh Lee, Jack Cheng, Dong Chuan Wu, Wei-Yong Lin
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 280 (2023)
The NMDA receptor hypofunction has been implicated in schizophrenia, memory impairment, and Alzheimer’s disease. Modulating the abundance of D-serine, a co-agonist of the NMDA receptor, is a strategy to treat symptoms of the NMDA receptor hypofunct
Externí odkaz:
https://doaj.org/article/c37ea5a29d8b4b35bac4ef618287eec7
Autor:
Chuan-Hsiu Liu, Mei-Ying Chen, Yueh-Hsiung Kuo, Jack Cheng, Li-Zhong Chang, Meng-Shiun Chang, Tsai-Ni Chuang, Wen-Tsong Hsieh, Yan-Ru Xiao, Bor-Tsang Wu, Wei-Yong Lin, Hsin-Ping Liu
Publikováno v:
Molecules, Vol 28, Iss 2, p 507 (2023)
Microglia are neuroglia in the brain with an innate immune function and participate in the progress of neurodegenerative diseases. Osthole (OST) is a coumarin derivative extracted from Cnidium monnieri and bears a microglia-antagonizing ability. Howe
Externí odkaz:
https://doaj.org/article/c39652f6e11045a0a538c16883faba61
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10181 (2022)
Background: Imidacloprid (IMD) is a widely used neonicotinoid-targeting insect nicotine acetylcholine receptors (nAChRs). However, off-target effects raise environmental concerns, including the IMD’s impairment of the memory of honeybees and rodent
Externí odkaz:
https://doaj.org/article/b5a04380da934e6ab277d156245e49c4
Autor:
Szu-Ju Chen, Sunderiya Dalanbaatar, Huey-Yi Chen, Shih-Jing Wang, Wei-Yong Lin, Po-Len Liu, Ming-Yen Tsai, Der-Cherng Chen, Yung-Hsiang Chen, Wen-Chi Chen
Publikováno v:
Life, Vol 12, Iss 8, p 1250 (2022)
Approximately 1 in 20 people develops kidney stones at some point in their life. Although the surgical removal of stones is common, the recurrence rate remains high and it is therefore important to prevent the occurrence of kidney stones. We chose As
Externí odkaz:
https://doaj.org/article/8fc0da1dbfa34188aa9e2c9f240da6eb