Výsledky vyhledávání - "Wei-Wen Jiang"

Akademický článek

Loss of TACC1 variant25 inducing cell proliferation and suppressing autophagy in head and neck squamous carcinoma

Autor: Pan Xu, Ran Zhao, Chen-Yang Zhang, Qian-Qian Zhang, Yong Wang, Jun Zhu, Wei-Wen Jiang

Publikováno v: Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)

Abstract Transforming acidic coiled-coil containing protein1 (TACC1) is closely related to transcription, translation and centrosome dynamics. Dysregulation of TACC1 is associated with multiple malignancies. Alternative splicing (AS) of TACC1 produce

Externí odkaz: https://doaj.org/article/a52d202e1eab4fa4b2899fbb419b8ce7

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Akademický článek

Upregulation of miR-31* is negatively associated with recurrent/newly formed oral leukoplakia.

Autor: Wen Xiao, Zhe-Xuan Bao, Chen-Yang Zhang, Xiao-Yun Zhang, Lin-Jun Shi, Zeng-Tong Zhou, Wei-Wen Jiang

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38648 (2012)

BackgroundOral leukoplakia (OLK) is a potentially malignant disorder of the oral cavity. However, the underlying mechanism of OLK is still unclear. In this study, we explore possible miRNAs involved in OLK.Methodology/principal findingsUsing miRNA mi

Externí odkaz: https://doaj.org/article/cfd873fb21c14d91812984c41da63dc3

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Supplemental Tables 6-11 from Notch1 Mutations Are Drivers of Oral Tumorigenesis

Autor: David Sidransky, Wei-Wen Jiang, Victor E. Velculescu, Samuel V. Angiuoli, David R. Riley, Christine L. McCord, Wayne Koch, Nishant Agrawal, Mariana Brait, Sian Jones, Kai Sun, Evgeny Izumchenko

Supplemental Tables 6-11. Supp. Table 6. List of all mutations identified in each of the normal samples. Supp. Table 7. List of the mutations in the unmatched OSCC and leukoplakia samples that were filtered-out as they were present in the normal samp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14eb19b96616ed49499ee146c008e36b
https://doi.org/10.1158/1940-6207.22526582.v1

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Supplemental Table 5 from Notch1 Mutations Are Drivers of Oral Tumorigenesis

Supplemental Table 5. List of 108 primer pairs designed by Fluidigm Assay Design Group and used in this study for NOTCH1 amplification. Table summarizes the GC-content, length distribution and location of the Access Array amplicons.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::250be6d942c03e57b184512c2dcc5426
https://doi.org/10.1158/1940-6207.22526588.v1

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Data from Notch1 Mutations Are Drivers of Oral Tumorigenesis

Disruption of NOTCH1 signaling was recently discovered in head and neck cancer. This study aims to evaluate NOTCH1 alterations in the progression of oral squamous cell carcinoma (OSCC) and compare the occurrence of these mutations in Chinese and Cauc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9c58be222d52a414c590912acf45b74
https://doi.org/10.1158/1940-6207.c.6545147.v1

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Supplemental Figure 1 from Notch1 Mutations Are Drivers of Oral Tumorigenesis

Supplemental Figure 1. List of all NOTCH1 mutations found in Chinese OSCC patients. A. Mutations identified in 22 tumor-normal pairs. B. Mutations found in 28 OSCC samples without matching normal control.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7c20cf2e54dd21bdc909a2c0f48dfe
https://doi.org/10.1158/1940-6207.22526600

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Supplemental Figure 3 from Notch1 Mutations Are Drivers of Oral Tumorigenesis

Supplemental Figure 3. A. Association between tumor stage of OSCC patients and NOTCH1 mutation-status. B. Table demonstrates differences in smoking and alcohol consumption rates between the OSCC and leukoplakia patients. C. Table demonstrates differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4022f78e6c4bed03034684d2d65f6b
https://doi.org/10.1158/1940-6207.22526594.v1

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Supplemental Tables 1-4 from Notch1 Mutations Are Drivers of Oral Tumorigenesis

Supplemental Tables 1-4. Supp. Table 1. A. List of all OSCC samples used in this study and clinical/pathological data. B. List of 22 matched tumor-normal pairs. Supp. Table 2. List of all normal samples used in this study and clinical/pathological da

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f41e95daad6b62115b30c3d13e9ab10
https://doi.org/10.1158/1940-6207.22526585.v1

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