Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Wei-Ru Huang"'
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The specifics of cell receptor-modulated avian reovirus (ARV) entry remain unknown. By using a viral overlay protein-binding assay (VOPBA) and an in-gel digestion coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS), we det
Externí odkaz:
https://doaj.org/article/3c8004c989cc4d468e1ff73746d79397
Autor:
Chao-Yu Hsu, Yun Jang, Wei-Ru Huang, Chi-Young Wang, Hsiao-Wei Wen, Pei-Chien Tsai, Cheng-Yao Yang, Muhammad Munir, Hung-Jen Liu
Publikováno v:
Vaccines, Vol 11, Iss 11, p 1666 (2023)
To simultaneously express and improve expression levels of multiple viral proteins of a porcine reproductive and respiratory syndrome virus (PRRSV), polycistronic baculovirus surface display vectors were constructed and characterized. We engineered p
Externí odkaz:
https://doaj.org/article/1c843177f0b44acdb4dec228c39524f3
Autor:
Ya-Yi Chen, Wei-Chen Yang, Yu-Kang Chang, Chi-Young Wang, Wei-Ru Huang, Jyun-Yi Li, Kuo-Pin Chuang, Hung-Yi Wu, Ching-Dong Chang, Brent L. Nielsen, Hung-Jen Liu
Publikováno v:
Veterinary Research, Vol 51, Iss 1, Pp 1-16 (2020)
Abstract To increase expression levels of the PCV2 Cap(d41) protein, novel baculovirus surface display vectors with multiple expression cassettes were constructed to create recombinant baculoviruses BacSC-Cap(d41), BacDD-2Cap(d41), BacDD-3Cap(d41), a
Externí odkaz:
https://doaj.org/article/cf73cf652e8c4e96963e65048e188db2
Autor:
Chao-Yu Hsu, Jing-Wen Huang, Wei-Ru Huang, I-Chun Chen, Ming-Shan Chen, Tsai-Ling Liao, Yu-Kang Chang, Muhammad Munir, Hung-Jen Liu
Publikováno v:
Viruses, Vol 15, Iss 2, p 523 (2023)
Our previous reports proved that the structural protein σA of avian reovirus (ARV) is an energy activator which can regulate cellular metabolism that is essential for virus replication. This study has further demonstrated that the ARV protein σA is
Externí odkaz:
https://doaj.org/article/d93f1ad3d2c141c19a19f57e829cce0a
Autor:
Hsu-Hung Tseng, Wei-Ru Huang, Ching-Yuan Cheng, Hung-Chuan Chiu, Tsai-Ling Liao, Brent L. Nielsen, Hung-Jen Liu
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Recent study in our laboratory has demonstrated that BEFV-induced autophagy via activation of the PI3K/Akt/NF-κB and Src/JNK pathways and suppression of the PI3K-AKt-mTORC1 pathway is beneficial for virus replication. In the current study, we found
Externí odkaz:
https://doaj.org/article/c32fecdc77844a8ab05fabafc654e29d
Autor:
Wei-Ru Huang, Pei-I Chi, Hung-Chuan Chiu, Jue-Liang Hsu, Brent L. Nielsen, Tsai-Ling Liao, Hung-Jen Liu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-19 (2017)
Abstract Although we have shown that avian reovirus (ARV) p17-mediated inhibition of Akt leads to induction of autophagy, the precise mechanisms remain largely unknown. This study has identified a specific mechanism by which ARV coordinately regulate
Externí odkaz:
https://doaj.org/article/0f15e8c5b9164b95ac8d3b6b24d492eb
Autor:
Hung-Chuan Chiu, Wei-Ru Huang, Tsai-Ling Liao, Hung-Yi Wu, Muhammad Munir, Wing-Ling Shih, Hung-Jen Liu
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162356 (2016)
The p17 protein of avian reovirus (ARV) causes cell cycle retardation in a variety of cell lines; however, the underlying mechanism(s) by which p17 regulates the cell cycle remains largely unknown. We demonstrate for the first time that p17 interacts
Externí odkaz:
https://doaj.org/article/6846bcb3cb2b4b84aeb5f938a092062f
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0133699 (2015)
Avian reovirus (ARV) protein p17 has been shown to regulate cell cycle and autophagy by activation of p53/PTEN pathway; nevertheless, it is still unclear how p53 and PTEN are activated by p17. Here, we report for the first time that p17 functions as
Externí odkaz:
https://doaj.org/article/274e08b10ffb418195a2806418f4721a
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138627 (2015)
Externí odkaz:
https://doaj.org/article/c8171ef207064a5ba735b9bd0c5863a2
Autor:
Wei-Ru Huang, 黃韋儒
106
Avian reovirus (ARV) is a common poultry viral pathogen, that causes respiratory diseases, viral arthritis, and malabsorption syndrome. Infection with ARV leads to the slow growth and weakness in poultry, which results in economic losses. El
Avian reovirus (ARV) is a common poultry viral pathogen, that causes respiratory diseases, viral arthritis, and malabsorption syndrome. Infection with ARV leads to the slow growth and weakness in poultry, which results in economic losses. El
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/u3t9k7