Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Wei-Ren Xu"'
Autor:
Ling Yin, Wei-Ren Xu, Zhi-Guo Wang, Da-Tong Zhang, Jiong Jia, Yan-Qing Ge, Yan Li, Jian-Wu Wang
Publikováno v:
ARKIVOC, Vol 2010, Iss 9, Pp 196-205 (2010)
Externí odkaz:
https://doaj.org/article/f3fb0dd8d819451880bdd69c9cf35641
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 12, Pp o3385-o3385 (2012)
In the title compound, C34H41N7O5·4H2O (systematic name: ethyl 3-{[2-({4-[(Z)-amino(hexyloxycarbonylimino)methyl]anilino}methyl)-1-methylbenzimidazole-5-carbonyl]pyridin-2-ylamino}propanoate tetrahydrate), the benzene and pyridine rings form dihedra
Externí odkaz:
https://doaj.org/article/f43058586e8544ceb83ce1662b16a597
Publikováno v:
Acta Crystallographica Section E, Vol 68, Iss 3, Pp o877-o877 (2012)
In the title compound, C19H17ClN2O2, the pyrazole ring makes dihedral angles of 6.97 (5) and 79.25 (1)°, respectively, with the phenyl and chlorophenyl rings, respectively. In the crystal, C—H...O hydrogen bonds are observed.
Externí odkaz:
https://doaj.org/article/30e936ac7c464e3e897102157e81442b
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48453 (2012)
As important members of nuclear receptor superfamily, Peroxisome proliferator-activated receptors (PPAR) play essential roles in regulating cellular differentiation, development, metabolism, and tumorigenesis of higher organisms. The PPAR receptors h
Externí odkaz:
https://doaj.org/article/9250f83d504e40b6929ec9013fde4d17
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38546 (2012)
Owing to their unique functions in regulating glucose, lipid and cholesterol metabolism, PPARs (peroxisome proliferator-activated receptors) have drawn special attention for developing drugs to treat type-2 diabetes. By combining the lipid benefit of
Externí odkaz:
https://doaj.org/article/2864561ae1dd4f03b124ae5d603d9430
Publikováno v:
Acta Crystallographica Section E, Vol 67, Iss 5, Pp o1130-o1130 (2011)
The title compound, C16H20O4, was obtained unintentionally as the byproduct of an attempted synthesis of methyl 3-(cyclopropylmethoxy)-4-hydroxybenzoate. In the crystal, the molecules are linked by intermolecular C—H...O interactions.
Externí odkaz:
https://doaj.org/article/1fcf36bd6fa3433e884b3f6acbcca0d2
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e28111 (2011)
The worldwide spread of H1N1 avian influenza and the increasing reports about its resistance to the current drugs have made a high priority for developing new anti-influenza drugs. Owing to its unique function in assisting viruses to bind the cellula
Externí odkaz:
https://doaj.org/article/6de5206c6afb4dc7ad58c0b07e1c7ad5
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 12, Pp o3258-o3258 (2010)
In the title compound, C11H19NO5, the five-membered pyrrolidine ring adopts an envelope conformation. The dihedral angles between the carboxyl group plane, the pyrrolidine ring and the methoxy group are 59.50 (3) and 62.02 (1)°, respectively. In the
Externí odkaz:
https://doaj.org/article/c3b7670d1c694ccf9db40e5893f46c70
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 8, Pp o2038-o2038 (2010)
In the title compound, C16H15BrO2, the dihedral angle between the benzene rings is 68.5 (2)°. In the crystal structure, molecules are linked by weak C—H...O hydrogen bonds into chains parallel to the b axis.
Externí odkaz:
https://doaj.org/article/f3a6e397abfa4352898d3d34f89cd230
Publikováno v:
Letters in Drug Design & Discovery. 17:772-786
Background: Phosphoinositide-3 kinases (PI3Ks) are key signaling molecules that affect a diverse array of biological processes in cells, including proliferation, differentiation, survival, and metabolism. The abnormal activity of PI3K signals is clos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62613c62bb925e14108a09596f2f5694
https://doi.org/10.2174/1570180816666190730163431
https://doi.org/10.2174/1570180816666190730163431