Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wei-Ren Ke"'
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 173:132-140
Although inhalation powder aerosols of antibiotics have been used to treat respiratory infections caused by Pseudomonas aeruginosa, biofilms are difficult to clear. Ciprofloxacin and D-amino acids (D-Met, D-Trp and D-Phe) were shown to facilitate P.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::291b580981c3d127cba55553a068ab77
https://doi.org/10.1016/j.ejpb.2022.03.003
https://doi.org/10.1016/j.ejpb.2022.03.003
Publikováno v:
Advanced drug delivery reviews. 191
Dry powder inhalers (DPIs) can be used with a wide range of drugs such as small molecules and biologics and offer several advantages for inhaled therapy. Early DPI products were intended to treat asthma and lung chronic inflammatory disease by admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b68dfbcd6853af9dfaa1ea67a0db62e
https://pubmed.ncbi.nlm.nih.gov/36191861
https://pubmed.ncbi.nlm.nih.gov/36191861
Autor:
Ahmed H. Albariqi, Wei-Ren Ke, Dipesh Khanal, Stefanie Kalfas, Patricia Tang, Warwick J Britton, John Drago, Hak-Kim Chan
biBackground:/i/bIvermectin has received worldwide attention as a potential COVID-19 treatment after showing antiviral activity against SARS-CoV-2iin vitro./iHowever, the pharmacokinetic limitations associated with oral administration have been postu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a7eb6fcd04bc0758dadda6301ac929
https://hdl.handle.net/2123/28304
https://hdl.handle.net/2123/28304
Publikováno v:
International Journal of Pharmaceutics. 632:122563
The aim of this research was to chemically analyse the distribution of drugs and excipients in pharmaceutical dry powder inhalation (DPI) aerosol particles of various sizes in solid state. The conventional wet assay of the chemical composition of par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c92ee857631912bca47f924c3cd3a6f
https://doi.org/10.1016/j.ijpharm.2022.122563
https://doi.org/10.1016/j.ijpharm.2022.122563
Publikováno v:
Aerosol and Air Quality Research. 19:688-697
Rotating drum chambers are simple and effective devices for retaining particles in the airborne state for prolonged periods. Many studies, including inhalation toxicology, environmental fate, and survivability of airborne pathogens, can benefit from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1347747a4404455adc0df21374d972a
https://doi.org/10.4209/aaqr.2018.05.0174
https://doi.org/10.4209/aaqr.2018.05.0174
Autor:
Philip Chi Lip Kwok, Hak-Kim Chan, Rachel Yoon Kyung Chang, Lan Chen, Donghao Chen, Patricia Tang, Wei-Ren Ke
Publikováno v:
Ann Transl Med
Inhaled drugs are routinely used for the treatment of respiratory-supported patients. To date, pressurized metered dose inhalers and nebulizers are the two platforms routinely employed in the clinical setting. The scarce utilization of the dry powder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9751f6ccfbef0249a8ad8b587bab55a4
https://pubmed.ncbi.nlm.nih.gov/33987294
https://pubmed.ncbi.nlm.nih.gov/33987294
Publikováno v:
International journal of pharmaceutics. 602
Spray drying is a rapid method for converting a liquid feed into dried particles for inhalation aerosols. Lactose is a major inhalation excipient used in spray-dried (SD) formulations. However, SD powders produced from solutions are usually amorphous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28ee03b865128ee947ca31324631641c
https://pubmed.ncbi.nlm.nih.gov/33862136
https://pubmed.ncbi.nlm.nih.gov/33862136
Publikováno v:
International journal of pharmaceutics. 591
Lactose is widely used as an approved excipient for dry powder inhaler (DPI) products. Spray drying technique is a rapid method for converting a liquid feed into inhalable dried particles. However, spray-dried (SD) lactose powders produced from solut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c48c1b5541a6c34e61db251c80c97bf
https://pubmed.ncbi.nlm.nih.gov/33069893
https://pubmed.ncbi.nlm.nih.gov/33069893
Publikováno v:
Analytical chemistry. 92(12)
Solid state chemical analysis of pharmaceutical inhalation aerosols at the individual particle level has been an analytical challenge. These particles can range from a few nanometers to micrometers and are a complex mixture of drugs and excipients. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832b6c99522c800e7f4d48e9eec44b44
https://pubmed.ncbi.nlm.nih.gov/32406232
https://pubmed.ncbi.nlm.nih.gov/32406232
Autor:
Chih-Chieh Chen, Chao-Ling Wu, Wei-Ren Ke, Huey-Dong Wu, Sheng-Hsiu Huang, Tzu-Hsuan Lin, Wei-Jhen Wang
Publikováno v:
Respiratory care. 65(7)
Soft mist inhalers (SMIs) generate aerosols with a smaller particle size than pressurized metered-dose inhalers (pMDIs). However, the whole-span particle size distribution (PSD) of SMIs and the optimal delivery method of SMIs during mechanical ventil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8612219f54aefb12cab9a1c0092c695f
https://pubmed.ncbi.nlm.nih.gov/32071134
https://pubmed.ncbi.nlm.nih.gov/32071134