Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Wei-Qiang Leow"'
Autor:
Yik Yan Chong, Sasinthiran Thiagarajan, Qiu Xuan Tan, Hui Jun Lim, Joey Wee-Shan Tan, Josephine Hendrikson, Gillian Ng, Ying Liu, Clara Yieh Lin Chong, Wanyu Guo, Nye Thane Ngo, Wei-Qiang Leow, Tracy Loh, Xin Xiu Sam, Tony Kiat Hon Lim, Mingzhe Cai, Chin Jin Seo, Jolene Si Min Wong, Khee Chee Soo, Claramae Shulyn Chia, Nicholas Brian Shannon, Chin-Ann Johnny Ong
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Peritoneal metastasis (PM), the regional progression of intra-abdominal malignancies, is a common sequelae of colorectal cancer (CRC). Immunotherapy is slated to be effective in generating long-lasting anti-tumour response as it utilizes the
Externí odkaz:
https://doaj.org/article/f5021bad349c4ba2a151b64ebfe4f276
Autor:
Vivian Chih-Wei Chen, Craig Ryan Joseph, Wharton O. Y. Chan, Wan Rong Sia, Qi Su, Xin Xiu Sam, Hemavathi Tamilarasan, Yun Yan Mah, Wei Lun Ng, Joe Yeong, Lin-Fa Wang, Thinesh L. Krishnamoorthy, Wei-Qiang Leow, Matae Ahn, Wan Cheng Chow
Publikováno v:
Viruses, Vol 16, Iss 10, p 1646 (2024)
Inflammasome is linked to many inflammatory diseases, including COVID-19 and autoimmune liver diseases. While severe COVID-19 was reported to exacerbate liver failure, we report a fatal acute-on-chronic liver failure (ACLF) in a stable primary biliar
Externí odkaz:
https://doaj.org/article/7d21d18c0b0e4d679d8734ac22353137
Autor:
Yi De Ian Koh, Wei-Qiang Leow
Publikováno v:
Journal of Liver Cancer, Vol 23, Iss 2, Pp 397-401 (2023)
Hepatic tuberculosis (HTB) is an uncommon manifestation of tuberculous infections, and there has been no proven causal link between HTB and hepatocellular carcinoma (HCC). We herein present a rare case of a synchronous presentation of HTB and HCC wit
Externí odkaz:
https://doaj.org/article/c3a963e1832f4ec7b29a899a3e0d7e01
Autor:
Cheen Fei Chin, Dwight L.A. Galam, Liang Gao, Bryan C. Tan, Bernice H. Wong, Geok-Lin Chua, Randy Y.J. Loke, Yen Ching Lim, Markus R. Wenk, Miao-Shan Lim, Wei-Qiang Leow, George B.B. Goh, Federico Torta, David L. Silver
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 17 (2023)
The liver has a high demand for phosphatidylcholine (PC), particularly in overnutrition, where reduced phospholipid levels have been implicated in the development of nonalcoholic fatty liver disease (NAFLD). Whether other pathways exist in addition t
Externí odkaz:
https://doaj.org/article/65986795ef3e486290872e1e79aa32e1
Autor:
Ah-Jung Jeon, Yue-Yang Teo, Karthik Sekar, Shay Lee Chong, Lingyan Wu, Sin-Chi Chew, Jianbin Chen, Raden Indah Kendarsari, Hannah Lai, Wen Huan Ling, Neslihan Arife Kaya, Jia Qi Lim, Adaikalavan Ramasamy, Gokce Oguz, Alexander Yaw-Fui Chung, Chung Yip Chan, Peng-Chung Cheow, Juinn Huar Kam, Krishnakumar Madhavan, Alfred Kow, Iyer Shridhar Ganpathi, Tony Kiat Hon Lim, Wei-Qiang Leow, Shihleone Loong, Tracy Jiezhen Loh, Wei Keat Wan, Gwyneth Shook Ting Soon, Yin Huei Pang, Boon Koon Yoong, Diana Bee-Lan Ong, Jasmine Lim, Vanessa H. de Villa, Rouchelle D.dela Cruz, Rawisak Chanwat, Jidapa Thammasiri, Glenn K. Bonney, Brian K. P. Goh, Greg Tucker-Kellogg, Roger Sik Yin Foo, Pierce K. H. Chow
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Conventional differential expression (DE) testing compares the grouped mean value of tumour samples to the grouped mean value of the normal samples, and may miss out dysregulated genes in small subgroup of patients. This is especi
Externí odkaz:
https://doaj.org/article/ac89eae58a5449229b3b4f7dcae89062
Autor:
Ah-Jung Jeon, Chukwuemeka George Anene-Nzelu, Yue-Yang Teo, Shay Lee Chong, Karthik Sekar, Lingyan Wu, Sin-Chi Chew, Jianbin Chen, Raden Indah Kendarsari, Hannah Lai, Wen Huan Ling, Neslihan Arife Kaya, Jia Qi Lim, Alexander Yaw Fui Chung, Peng-Chung Cheow, Juinn Huar Kam, Krishnakumar Madhavan, Alfred Kow, Iyer Shridhar Ganpathi, Tony Kiat Hon Lim, Wei-Qiang Leow, Shihleone Loong, Tracy Jiezhen Loh, Wei Keat Wan, Gwyneth Shook Ting Soon, Yin Huei Pang, Boon Koon Yoong, Diana Bee-Lan Ong, Jasmine Lim, Vanessa H. de Villa, Rouchelle D. dela Cruz, Rawisak Chanwat, Jidapa Thammasiri, Glenn K. Bonney, Brian K.P. Goh, Roger Sik Yin Foo, Pierce Kah-Hoe Chow
Publikováno v:
JHEP Reports, Vol 5, Iss 6, Pp 100715- (2023)
Background & Aims: Lifestyle and environmental-related exposures are important risk factors for hepatocellular carcinoma (HCC), suggesting that epigenetic dysregulation significantly underpins HCC. We profiled 30 surgically resected tumours and the m
Externí odkaz:
https://doaj.org/article/60b0d493517247318069a8fdb601a422
Autor:
Cowan Ho, Zitong Zhao, Xiu Fen Chen, Jan Sauer, Sahil Ajit Saraf, Rajasa Jialdasani, Kaveh Taghipour, Aneesh Sathe, Li-Yan Khor, Kiat-Hon Lim, Wei-Qiang Leow
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Colorectal cancer is one of the most common cancers worldwide, accounting for an annual estimated 1.8 million incident cases. With the increasing number of colonoscopies being performed, colorectal biopsies make up a large proportion of any
Externí odkaz:
https://doaj.org/article/c49483aae1e44f9b985188770bcc339d
Autor:
Wei-Qiang Leow, Anthony Wing-Hung Chan, Paulo Giovanni L. Mendoza, Regina Lo, Kihan Yap, Haeryoung Kim
Publikováno v:
Clinical and Molecular Hepatology, Vol 29, Iss Suppl, Pp S302-S318 (2023)
Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases characterized by fatty accumulation in hepatocytes, ranging from steatosis, non-alcoholic steatohepatitis, to cirrhosis. While histopathological evaluation of liver biopsies plays a
Externí odkaz:
https://doaj.org/article/832d4fc2c32140bc8b522cee9129c2bb
Autor:
Wei-Qiang Leow, Pierre Bedossa, Feng Liu, Lai Wei, Kiat-Hon Lim, Wei-Keat Wan, Yayun Ren, Jason Pik-Eu Chang, Chee-Kiat Tan, Aileen Wee, George Boon-Bee Goh
Publikováno v:
Diagnostics, Vol 10, Iss 9, p 643 (2020)
Background: Many clinical trials with potential drug treatment options for non-alcoholic fatty liver disease (NAFLD) are focused on patients with non-alcoholic steatohepatitis (NASH) stages 2 and 3 fibrosis. As the histological features differentiati
Externí odkaz:
https://doaj.org/article/ad1a9f61e01841329960391bf728a74e
Autor:
Phuong H. D. Nguyen, Martin Wasser, Chong Teik Tan, Chun Jye Lim, Hannah L. H. Lai, Justine Jia Wen Seow, Ramanuj DasGupta, Cheryl Z. J. Phua, Siming Ma, Jicheng Yang, Sheena D/O Suthen, Wai Leong Tam, Tony K. H. Lim, Joe Yeong, Wei Qiang Leow, Yin Huei Pang, Gwyneth Soon, Tracy Jiezhen Loh, Wei Keat Wan, Chung Yip Chan, Peng Chung Cheow, Han Chong Toh, Alfred Kow, Yock Young Dan, Juinn Huar Kam, Shridhar Iyer, Krishnakumar Madhavan, Alexander Chung, Glenn K. Bonney, Brian K. P. Goh, Naiyang Fu, Victor C. Yu, Weiwei Zhai, Salvatore Albani, Pierce K. H. Chow, Valerie Chew
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
In order to design cancer immune therapies, it is important to understand how tumours evade the immune response that is mounted against them. Authors here analyse the distribution and properties of immune cells in hepatocellular carcinoma and describ
Externí odkaz:
https://doaj.org/article/2648047cd2d74e93ad29e2f0557f8fa3