Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wei-Pu Wu"'
Autor:
Mathieu F. Bakhoum, Wei-Pu Wu, Eugenia C. White, Jesse D. Sengillo, Christian Sanfilippo, Marcelle M. Morcos, K. Bailey Freund, Henry D. Perry, David Sarraf, Stephen H. Tsang
Publikováno v:
Graefe's Archive for Clinical and Experimental Ophthalmology. 256:583-588
PURPOSE: The mitochondrial DNA point mutation A3243G leads to a spectrum of syndromes ranging from MIDD to MELAS. Ocular manifestations include pattern macular dystrophy and concentric perifoveal atrophy. Given the high metabolic demand of corneal en
Autor:
Luis Bonet-Ponce, Chyuan-Sheng Lin, Lijuan Zhang, Wei-Pu Wu, Chun-Wei Hsu, Yi-Ting Tsai, Jianhai Du, Sally Justus, Yading Jia, James B. Hurley, Jimmy Duong, Stephen H. Tsang, Wen-Hsuan Wu, Vinit B. Mahajan, Shuang Wang
Publikováno v:
Journal of Clinical Investigation. 126:4659-4673
Retinitis pigmentosa (RP) encompasses a diverse group of Mendelian disorders leading to progressive degeneration of rods and then cones. For reasons that remain unclear, diseased RP photoreceptors begin to deteriorate, eventually leading to cell deat
Autor:
Wen-Hsuan Wu, Pei-Yin Su, Christine L. Xu, Yi-Ting Tsai, Ruben Jauregui, Karen Sophia Park, Wei-Pu Wu, Xuan Cui, Stephen H. Tsang, Chyuan-Sheng Lin, Ting-Ting Lee, Sally Justus
Publikováno v:
Ophthalmology. 125(9)
Purpose To develop a universal gene therapy to overcome the genetic heterogeneity in retinitis pigmentosa (RP) resulting from mutations in rhodopsin ( RHO ). Design Experimental study for a combination gene therapy that uses both gene ablation and ge
Autor:
Ming Kai Pan, Elan D. Louis, Sheng-Han Kuo, Jie Wang, Ravi J. Louis, Chi-Ying Lin, Wei Pu Wu, Jesus Gutierrez, Phyllis L. Faust, Jyun-you Liou
Publikováno v:
Annals of neurology. 80(3)
Essential tremor (ET) patients have abnormal climbing fiber (CF) synapses in the parallel fiber territory in the cerebellum, and these abnormal CF synapses are inversely correlated with tremor severity. We therefore examined CF synaptic pathology in
Autor:
Stephen H. Tsang, Alexander G. Bassuk, Wei-Pu Wu, Vinit B. Mahajan, Chun-Wei Hsu, Sally Justus, Yi-Ting Tsai, Andrew Zheng, Wen-Hsuan Wu
Publikováno v:
Genome Editing ISBN: 9783319341460
The future of precision medicine, genome editing has gained momentum in the field of ophthalmology because of the eye’s amenability to genetic interventions. The eye is an ideal target for gene therapy due to its accessibility, ease of noninvasive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b39d3adf9776fe9098655527f237a7ef
https://doi.org/10.1007/978-3-319-34148-4_9
https://doi.org/10.1007/978-3-319-34148-4_9
Autor:
Susanne Koch, Stephen H. Tsang, Wen-Hsuan Wu, Chyuan-Sheng Lin, Wei-Pu Wu, Luis Bonet-Ponce, Yi-Ting Tsai, Chun-Wei Hsu, Jimmy Duong
Publikováno v:
The Journal of clinical investigation. 125(9)
Recent gene therapy progress has raised the possibility that vision loss caused by inherited retinal degeneration can be slowed or prevented. Unfortunately, patients are not usually diagnosed until enough degeneration has occurred that the deteriorat
Autor:
Lijuan Zhang1,2,3, Jianhai Du4, Justus, Sally1,2, Chun-Wei Hsu1,2, Bonet-Ponce, Luis5, Wen-Hsuan Wu1,2, Yi-Ting Tsai1,2, Wei-Pu Wu1,2, Yading Jia2, Duong, Jimmy K.6, Mahajan, Vinit B.7, Chyuan-Sheng Lin8, Shuang Wang6, Hurley, James B.4, Tsang, Stephen H.1,2,9 sht2@columbia.edu, Zhang, Lijuan (AUTHOR), Du, Jianhai (AUTHOR), Hsu, Chun-Wei (AUTHOR), Wu, Wen-Hsuan (AUTHOR), Tsai, Yi-Ting (AUTHOR)
Publikováno v:
Journal of Clinical Investigation. Dec2016, Vol. 126 Issue 12, p4659-4673. 15p. 8 Graphs.
Autor:
Koch, Susanne F.1,2, Yi-Ting Tsai1,2,3, Duong, Jimmy K.4, Wen-Hsuan Wu1,2, Chun-Wei Hsu1,2, Wei-Pu Wu1,2, Bonet-Ponce, Luis5, Chyuan-Sheng Lin6, Tsang, Stephen H.1,2,3,6 sht2@columbia.edu
Publikováno v:
Journal of Clinical Investigation. 9/1/2015, Vol. 125 Issue 9, p3704-3713. 10p. 2 Color Photographs, 1 Diagram, 5 Graphs.