Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Wei-Lan Yeh"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Pulmonary fibrosis features in damaged pulmonary structure or over-produced extracellular matrix and impaired lung function, leading to respiratory failure and eventually death. Fibrotic lungs are characterized by the secretion of pro-fib
Externí odkaz:
https://doaj.org/article/bb17719baa3247afb27b3a7064ae15e3
Autor:
Yen-Chang Chen, Chen-Teng Wu, Jia-Hong Chen, Cheng-Fang Tsai, Chen-Yun Wu, Pei-Chun Chang, Wei-Lan Yeh
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-9 (2022)
Abstract Migration and metastasis commonly happen to triple-negative breast cancer (TNBC) patients with advanced diseases. In many studies, it has been suggested that epithelial-mesenchymal transition (EMT) is one of the key mechanisms triggering can
Externí odkaz:
https://doaj.org/article/76922b2bdf0b42238f90a7e4f591f3c7
Autor:
Ching-Kai Shen, Bor-Ren Huang, Vichuda Charoensaensuk, Liang-Yo Yang, Cheng-Fang Tsai, Yu-Shu Liu, Sheng-Wei Lai, Dah-Yuu Lu, Wei-Lan Yeh, Chingju Lin
Publikováno v:
Nutrients, Vol 15, Iss 23, p 4854 (2023)
We previously reported that proinflammatory cytokines, particularly tumor necrosis factor (TNF)-α, promoted tumor migration, invasion, and proliferation, thus worsening the prognosis of glioblastoma (GBM). Urolithins, the potent metabolites produced
Externí odkaz:
https://doaj.org/article/2853ccb729d74b57ab21728b519e38aa
Autor:
Ching-Kai Shen, Bor-Ren Huang, Vichuda Charoensaensuk, Liang-Yo Yang, Cheng-Fang Tsai, Yu-Shu Liu, Dah-Yuu Lu, Wei-Lan Yeh, Chingju Lin
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1533 (2023)
Bradykinin is a small active peptide and is considered an inflammatory mediator in several pathological conditions. Bradykinin exerts its effects by coupling to its receptors, including bradykinin B1 (B1R) and bradykinin B2. B1R has been implicated i
Externí odkaz:
https://doaj.org/article/a9c0c824964145faa5200fd73dfc87c8
Autor:
Wei-Lan Yeh, Bor-Ren Huang, Guan-Wei Chen, Vichuda Charoensaensuk, Cheng-Fang Tsai, Liang-Yo Yang, Dah-Yuu Lu, Mao-Kai Chen, Chingju Lin
Publikováno v:
Nutrients, Vol 14, Iss 24, p 5402 (2022)
Macrophages and microglia are highly versatile cells that can be polarized into M1 and M2 phenotypes in response to diverse environmental stimuli, thus exhibiting different biological functions. In the central nervous system, activated resident macro
Externí odkaz:
https://doaj.org/article/38fdffc7ec8e4529a0c6372425502b15
Autor:
Yen-Chang Chen, Jia-Hong Chen, Cheng-Fang Tsai, Chen-Teng Wu, Miao-Hsiang Wu, Pei-Chun Chang, Wei-Lan Yeh
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Metastasis represents an advanced stage of cancers, and matrix metalloproteinases are critical regulators. Calcium signal is crucial for appropriate cell behaviors. The efficacy and effects of calcium channel blockers in treating cancers
Externí odkaz:
https://doaj.org/article/7c917c12d8894107925d37d57de352f0
Regulatory Effects of Quercetin on M1/M2 Macrophage Polarization and Oxidative/Antioxidative Balance
Autor:
Cheng-Fang Tsai, Guan-Wei Chen, Yen-Chang Chen, Ching-Kai Shen, Dah-Yuu Lu, Liang-Yo Yang, Jia-Hong Chen, Wei-Lan Yeh
Publikováno v:
Nutrients, Vol 14, Iss 1, p 67 (2021)
Macrophage polarization plays essential and diverse roles in most diseases, such as atherosclerosis, adipose tissue inflammation, and insulin resistance. Homeostasis dysfunction in M1/M2 macrophage polarization causes pathological conditions and infl
Externí odkaz:
https://doaj.org/article/d8c53c1064b943aab86272a98676428c
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-12 (2017)
Abstract Background Mesenchymal stem cells in tumor microenvironment can influence therapeutic responses in various types of cancers. For triple negative breast cancer, chemotherapy remains the mainstay of standard treatment. Our aim was to investiga
Externí odkaz:
https://doaj.org/article/fa271110590a40a7875b302dfb05c2bb
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Background: Leptin is considered a tumorigenic adipokine, suggested to promote tumorigenesis and progression in many cancers. On the other hand, intercellular adhesion molecule-1 (ICAM-1) shows altered expression in a variety of benign and malignant
Externí odkaz:
https://doaj.org/article/55ea5fb51ef747d38c820922b8685faa
Autor:
Chingju Lin, Hsiao-Yun Lin, Jia-Hong Chen, Wen-Pei Tseng, Pei-Ying Ko, Yu-Shu Liu, Wei-Lan Yeh, Dah-Yuu Lu
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 4, Pp 8844-8860 (2015)
Increasing studies suggest that inflammatory processes in the central nervous system mediated by microglial activation plays an important role in numerous neurodegenerative diseases. Development of planning for microglial suppression is considered a
Externí odkaz:
https://doaj.org/article/b8424a09e70242689b9dd82070782690