Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Wei-Jen Chung"'
Autor:
Jill Fenaux, Xin Fang, Yao-ming Huang, Cristina Melero, Caroline Bonnans, Earth Light Lowe, Tiziana Palumbo, Cecilia Lay, Zuoan Yi, Aileen Zhou, Mauro Poggio, Wei-Jen Chung, Sophia R. Majeed, Dylan Glatt, Alice Chen, Maike Schmidt, Clarissa C. Lee
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTImmune checkpoint inhibition (ICI) has revolutionized cancer treatment; however, only a subset of patients benefit long term. Therefore, methods for identification of novel checkpoint targets and development of therapeutic interventions again
Externí odkaz:
https://doaj.org/article/5b1a4e2f8e6a433f9b2901ba88665afe
Autor:
Kristin M. Zimmerman Savill, Brian B. Lee, Jason Oeh, Jie Lin, Eva Lin, Wei-Jen Chung, Amy Young, Wennie Chen, Monika Miś, Kathryn Mesh, Jeffrey Eastham, Florian Gnad, Zhaoshi Jiang, Eric W. Stawiski, Benjamin Haley, Anneleen Daemen, Xiaojing Wang, Hartmut Koeppen, Zora Modrusan, Scott E. Martin, Deepak Sampath, Kui Lin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
How resistance to different classes of AKT inhibitors can emerge is unclear. Here, the authors show that resistance to allosteric inhibitors is mainly due to mutation of AKT1 while the ATP competitive resistance is driven by activation of PIM kinases
Externí odkaz:
https://doaj.org/article/942eedd4f9f14214ba862fbc21b1991f
Autor:
Chin-Te Jung, Chih-Hong Sun, Min-Fang Lien, Chih-Shyang Chang, Wei-Jen Chung, Hong-Yang Lin, Ping-Ying Tsai
Publikováno v:
Geography, Environment, Sustainability, Vol 6, Iss 1, Pp 37-54 (2013)
The lack of integration and communication of various geographic information services (GI services) has resulted in many duplication collection of earth observation data, and challenges of semantic interoperability. This paper proposes an ontology-bas
Externí odkaz:
https://doaj.org/article/6570fd7ca26346f6932d26eb205aa3dd
Autor:
Yi-Chang Liu, I-Hsuan Lin, Wei-Jen Chung, Wensi S Hu, Wailap Victor Ng, Chi-Yu Lu, Tsung-Yen Huang, Hung-Wei Shu, Kwang-Jen Hsiao, Shih-Feng Tsai, Chuan-Hsiung Chang, Chao-Hsiung Lin
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35304 (2012)
Mycoplasma fermentans is a potent human pathogen which has been implicated in several diseases. Notably, its lipid-associated membrane proteins (LAMPs) play a role in immunomodulation and development of infection-associated inflammatory diseases. How
Externí odkaz:
https://doaj.org/article/5707b0e658e74354b19bc76249c7e9dc
Autor:
Wei-Jen Chung, 鍾維人
97
This thesis present the tree structure detector of Haar-like feature for face detector, a training speedup tick, and the feature scale correct method. In the feature training of Adaboost algorithm, the process adapt much more features for com
This thesis present the tree structure detector of Haar-like feature for face detector, a training speedup tick, and the feature scale correct method. In the feature training of Adaboost algorithm, the process adapt much more features for com
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/23685810989949639638
Autor:
Wei-Jen Chung, 鍾偉仁
86
The main purpose of this research is to use Tabu Search method as the basis to develop a good heuristic algorithm for the Mixed Rural Postman Problem with Hierarchical Constraints. We propose two initial solution methods and three neighborhoo
The main purpose of this research is to use Tabu Search method as the basis to develop a good heuristic algorithm for the Mixed Rural Postman Problem with Hierarchical Constraints. We propose two initial solution methods and three neighborhoo
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/71693968664780084981
Autor:
Wei-Jen Chung, 鍾唯任
92
Mycoplasmas are the smallest free-living bacteria. They all have small genome (580-2200 kb) with high percentage of AT content (67 to 76%). Nowadays, more than 150 species of mycoplasma have been discovered, and they are widely distributed in
Mycoplasmas are the smallest free-living bacteria. They all have small genome (580-2200 kb) with high percentage of AT content (67 to 76%). Nowadays, more than 150 species of mycoplasma have been discovered, and they are widely distributed in
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/57778958449849535577
Autor:
Xin Fang, Wei-Jen Chung, Jill Fenaux, Alice Chen, Nizar Batada, Maike Schmidt, Sophia R. Majeed, Sushil Kumar, Steven Pitts
Publikováno v:
Cancer Research. 82:603-603
Using large genetic and phenotypic datasets, 23andMe has developed a novel immuno-oncology target-identification platform. 23andMe has assembled a genetic database of nearly 12 million individuals, with 80 percent consented to research, coupled with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::811fc683b5583a4330ef7f37d7305e8c
https://doi.org/10.1158/1538-7445.am2022-603
https://doi.org/10.1158/1538-7445.am2022-603
Autor:
Jason E. Long, Bu-Er Wang, Florian Gnad, Oded Foreman, Melissa R. Junttila, Jason H. Cheng, Mallika Singh, Anneleen Daemen, Christopher Tran, Wei-Jen Chung, Jonathan E. Cooper, Zora Modrusan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance RAS mutant cancers represent a large unmet clinical need. Kras mutant genetically engineered mouse models (GEMMs) of cancer recapitulate disease characteristics and are relied upon preclinically to validate targets and test therapies. Ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5689d4ac61dca3c5066dc1b4f06a0e
http://europepmc.org/articles/PMC5754767
http://europepmc.org/articles/PMC5754767
Autor:
Bu-Er Wang, Teemu T. Junttila, Wendy Sandoval, Oded Foreman, Zora Modrusan, Matthew Wongchenko, Jeffrey Eastham-Anderson, Qingling Li, Melissa R. Junttila, Jason E. Long, Ji Li, Richard A.D. Carano, Yibing Yan, Dorothee Nickles, Wei-Jen Chung, Johannes Riegler
Publikováno v:
Cell Death and Differentiation
Emerging research suggests that multiple tumor compartments can influence treatment responsiveness and relapse, yet the search for therapeutic resistance mechanisms remains largely focused on acquired genomic alterations in cancer cells. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66b1584dd6f2010cde3581866cf8d8f
https://pubmed.ncbi.nlm.nih.gov/30824837
https://pubmed.ncbi.nlm.nih.gov/30824837