Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Wei-Hwa Lee"'
Autor:
Ko-Ta Chen, Chi-Tai Yeh, Vijesh Kumar Yadav, Narpati Wesa Pikatan, Iat-Hang Fong, Wei-Hwa Lee, Yen-Shuo Chiu
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e28094- (2024)
1. Abstract: Objective: Osteoarthritis (OA), the most prevalent form of arthritis, impacts approximately 10% of men and 18% of women aged above 60 years. Currently, a complete cure for OA remains elusive, making clinical management challenging. The t
Externí odkaz:
https://doaj.org/article/cc2ef0d17d614a4095f3913ae5d3da08
Autor:
Shao-Cheng Liu, Yang-Che Wu, Chih-Ming Huang, Ming-Shou Hsieh, Ting-Yi Huang, Chin-Sheng Huang, Tung-Nien Hsu, Mao-Suan Huang, Wei-Hwa Lee, Chi-Tai Yeh, Chun-Shu Lin
Publikováno v:
Oncogenesis, Vol 10, Iss 2, Pp 1-18 (2021)
Abstract Locally advanced oral squamous cell carcinoma (OSCC) requires multimodal therapy, including surgery and concurrent chemoradiotherapy (CCRT). CCRT-resistant and recurrent cancer has a poor prognosis. We investigated the effects of Bruton’s
Externí odkaz:
https://doaj.org/article/4f72df9b96cb4851b97f483a721756ee
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-7 (2020)
Abstract Background Glioblastoma multiforme (GBM) is one of the most aggressive malignant brain tumors. Intracranial GBM metastases to the spine are rarely detected clinically. Secondary gliosarcomas after treatment of primary GBM are rarely describe
Externí odkaz:
https://doaj.org/article/7d071661f87545f98038053e5b36c899
Autor:
Kuang-Tai Kuo, Wen-Chien Huang, Oluwaseun Adebayo Bamodu, Wei-Hwa Lee, Chun-Hua Wang, M. Hsiao, Liang-Shun Wang, Chi-Tai Yeh
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)
Abstract Background Lung cancer is the leading cause of cancer death worldwide. Recently, epigenetic dysregulation has been known to promote tumor progression and therefore may be a therapeutic target for anticancer therapy. JARID1B, a member of hist
Externí odkaz:
https://doaj.org/article/c0553b6b00744a35b3107a665a7a9a26
Autor:
Yu-Kai Su, Oluwaseun Adebayo Bamodu, I-Chang Su, Narpati Wesa Pikatan, Iat-Hang Fong, Wei-Hwa Lee, Chi-Tai Yeh, Hsiao-Yean Chiu, Chien-Min Lin
Publikováno v:
Pharmaceuticals, Vol 14, Iss 9, p 876 (2021)
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, with a median duration of survival of approximately 14 months after diagnosis. High resistance to chemotherapy remains a major problem. Previously, BTK has been shown to b
Externí odkaz:
https://doaj.org/article/11571c7ebe6543189e37fcfcd10e3c1b
Autor:
Shih-Jung Liu, Shun-Tai Yang, Shu-Mei Chen, Yin-Chen Huang, Wei-Hwa Lee, Jui Ho, Yin-Chun Chen, Yuan-Yun Tseng
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Background: Malignant gliomas (MGs) are highly chemotherapy-resistant. Temozolomide (TMZ) and carmustine (BiCNU) are alkylating agents clinically used for treating MGs. However, their effectiveness is restrained by overexpression of the DNA repair pr
Externí odkaz:
https://doaj.org/article/3c56cf15b42e4fa68f3bb6c68bbb2396
Autor:
Jiann Ruey Ong, Oluwaseun Adebayo Bamodu, Nguyen Viet Khang, Yen-Kuang Lin, Chi-Tai Yeh, Wei-Hwa Lee, Yih-Giun Cherng
Publikováno v:
Cells, Vol 10, Iss 1, p 178 (2021)
Hepatocellular carcinoma (HCC) is one of the most diagnosed malignancies and a leading cause of cancer-related mortality globally. This is exacerbated by its highly aggressive phenotype, and limitation in early diagnosis and effective therapies. The
Externí odkaz:
https://doaj.org/article/fd7d1e37bfa14e8bbbdcbb49df68b4ce
Publikováno v:
Journal of Functional Foods, Vol 21, Iss , Pp 406-417 (2016)
The effects of capsaicin (CAPS) on protein glycation and the subsequent formation of advanced glycation endproducts (AGEs) were assessed. In vitro glycation assays showed that CAPS retards the late stages of glycation and crosslinking reaction. The d
Externí odkaz:
https://doaj.org/article/58cf9d19c16d473c9e64df8c84315339
Autor:
Hang-Lung Chang, Oluwaseun Adebayo Bamodu, Jiann-Ruey Ong, Wei-Hwa Lee, Chi-Tai Yeh, Jo-Ting Tsai
Publikováno v:
Cells, Vol 9, Iss 4, p 1020 (2020)
Background: With recorded under-performance of current standard therapeutic strategies as highlighted by high rates of post-treatment (resection or local ablation) recurrence, resistance to chemotherapy, poor overall survival, and an increasing globa
Externí odkaz:
https://doaj.org/article/77ccdc0b0f164129bea534799a8a7800
Autor:
Shiue-Wei Lai, Oluwaseun Adebayo Bamodu, Jia-Hong Chen, Alexander TH Wu, Wei-Hwa Lee, Tsu-Yi Chao, Chi-Tai Yeh
Publikováno v:
Cells, Vol 9, Iss 4, p 911 (2020)
The role and therapeutic promise of poly-ADP ribose polymerase (PARP) inhibitors in anticancer chemotherapy are increasingly being explored, particularly in adjuvant or maintenance therapy, considering their low efficacy as monotherapy agents and the
Externí odkaz:
https://doaj.org/article/eef2f579eb7347209010b6dc1faee2d1