Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Wei-Guo Dai"'
Autor:
Yanbin Huang, Wei-Guo Dai
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 1, Pp 18-25 (2014)
The solid dispersion has become an established solubilization technology for poorly water soluble drugs. Since a solid dispersion is basically a drug–polymer two-component system, the drug–polymer interaction is the determining factor in its desi
Externí odkaz:
https://doaj.org/article/880f29c1784542a3802fe793141b203a
Publikováno v:
Acta Physico-Chimica Sinica. 33:960-967
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303c57f3355ac202aba65a0c82dd9877
https://doi.org/10.3866/pku.whxb201702086
https://doi.org/10.3866/pku.whxb201702086
Autor:
Wei-Guo Dai, Yanbin Huang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 4, Iss 1, Pp 18-25 (2014)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
The solid dispersion has become an established solubilization technology for poorly water soluble drugs. Since a solid dispersion is basically a drug–polymer two-component system, the drug–polymer interaction is the determining factor in its desi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6060854e78508fcd836732a2e668982
http://www.sciencedirect.com/science/article/pii/S2211383513000968
http://www.sciencedirect.com/science/article/pii/S2211383513000968
Publikováno v:
Materials Science Forum. :926-929
A new kind of passive underwater acoustic sensor based on fiber Bragg grating is reported. The pressure sensitivity of the sensor is enhanced three orders of magnitude being packaged with polymer material, which is a foundation for underwater acousti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::887c3f8d2d873a160394a7bdda2c0bf6
https://doi.org/10.4028/www.scientific.net/msf.663-665.926
https://doi.org/10.4028/www.scientific.net/msf.663-665.926
Autor:
Wei-Guo Dai
Publikováno v:
International Journal of Pharmaceutics. 393:1-16
Drug precipitation in vivo is often an undesirable outcome after administration of a drug formulation into a human body. It may reduce drug concentration for immediate action, leading to a delayed or reduced efficacy. There are few practical in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32ea0f5530bd19ca76d34d62c079133
https://doi.org/10.1016/j.ijpharm.2010.03.040
https://doi.org/10.1016/j.ijpharm.2010.03.040
Publikováno v:
International Journal of Pharmaceutics. 355:31-37
In this study, we screened surfactants and their combinations at low concentrations as potentially potent inhibitors of drug precipitation in an aqueous medium. Nine surfactants (including Pluronic F127, Pluronic F108, and Pluronic F68) were evaluate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee44ff4a0f4dac5954f864b46a190e42
https://doi.org/10.1016/j.ijpharm.2007.12.015
https://doi.org/10.1016/j.ijpharm.2007.12.015
Publikováno v:
Journal of Pharmaceutical Sciences. 96:2957-2969
A precipitation screening method using a 96‐well microtiter plate was developed to evaluate in vitro drug precipitation kinetics of liquid formulations for poorly water‐soluble compounds, using milligram quantities of compounds and milliliter vol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d82e772a0476bd04d2c3dd535412fe
https://doi.org/10.1002/jps.20886
https://doi.org/10.1002/jps.20886
Publikováno v:
International Journal of Pharmaceutics. 342:201-207
In this study, we present a novel approach of nanosizing a drug/polymeric complex to increase both solubility and dissolution rate of poorly water-soluble compounds. A hydrophilic polymer, lambda-carrageenan, was first complexed with a model poorly w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ce103e8ff78aca4958ae021f105e4a2
https://doi.org/10.1016/j.ijpharm.2007.04.032
https://doi.org/10.1016/j.ijpharm.2007.04.032
Autor:
Wei-Guo Dai, Liang C. Dong
Publikováno v:
International Journal of Pharmaceutics. 336:58-66
An insulin/lauryl sulfate complex was prepared by hydrophobic ion pairing (HIP). The physiochemical and biological properties of the HIP complex were characterized using octanol/water partition measurement, isothermal titration calorimetry (ITC), ult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cead2ae10949f628f6bc4574c315df
https://doi.org/10.1016/j.ijpharm.2006.11.035
https://doi.org/10.1016/j.ijpharm.2006.11.035
Autor:
J. Scicinski, Y. Xu, Jing Chen, Gary Eichenbaum, Ludo Edmond Josephine Kennis, Liang C. Dong, Crystal Pollock-Dove, Claire Mackie, Anton Megens, Wei-Guo Dai, D. Ashton, J. Evans, W. van Osdol, H. Borghys, Joseph Vu Nguyen, Shaoling Sunnyvale Li
Publikováno v:
Journal of Pharmaceutical Sciences. 95:883-895
In this paper, we present a preclinical approach for evaluating the feasibility of applying controlled-release (CR) oral drug delivery to increase the duration of exposure and lower the C max of compounds in a lead series of short half-life atypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b31c146198a7f93a0593e54b8f74bf
https://doi.org/10.1002/jps.20550
https://doi.org/10.1002/jps.20550