Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Wei-Gang Qiu"'
Autor:
Sherwood R. Casjens, Lia Di, Saymon Akther, Emmanuel F. Mongodin, Benjamin J. Luft, Steven E. Schutzer, Claire M. Fraser, Wei-Gang Qiu
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-24 (2018)
Abstract Background With approximately one-third of their genomes consisting of linear and circular plasmids, the Lyme disease agent cluster of species has the most complex genomes among known bacteria. We report here a comparative analysis of plasmi
Externí odkaz:
https://doaj.org/article/adc6f51a7be94c909310a4e30ce0f580
Autor:
Yözen Hernández, Rocky Bernstein, Pedro Pagan, Levy Vargas, William McCaig, Girish Ramrattan, Saymon Akther, Amanda Larracuente, Lia Di, Filipe G. Vieira, Wei-Gang Qiu
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-7 (2018)
Abstract Background Automated bioinformatics workflows are more robust, easier to maintain, and results more reproducible when built with command-line utilities than with custom-coded scripts. Command-line utilities further benefit by relieving bioin
Externí odkaz:
https://doaj.org/article/0275901365564981b4ea66b2e6175b50
Autor:
Wei-Gang Qiu, Alla Polotskaia, Gu Xiao, Lia Di, Yuhan Zhao, Wenwei Hu, John Philip, Ronald C. Hendrickson, Jill Bargonetti
Publikováno v:
npj Breast Cancer, Vol 3, Iss 1, Pp 1-9 (2017)
Personalized medicine: Mutated tumors respond to therapy Mutations in the p53 tumor suppressor gene could offer a predictive biomarker of response to certain drugs in triple-negative breast cancer. Jill Bargonetti from Hunter College in New York, USA
Externí odkaz:
https://doaj.org/article/b2c5b334b48243aca21c4d45cdb91aa3
Autor:
Wei-Gang Qiu, John F. Bruno, William D. McCaig, Yun Xu, Ian Livey, Martin E. Schriefer, Benjamin J. Luft
Publikováno v:
Emerging Infectious Diseases, Vol 14, Iss 7, Pp 1097-1104 (2008)
The A and B clones of Borrelia burgdorferi sensu stricto, distinguished by outer surface protein C (ospC) gene sequences, are commonly associated with disseminated Lyme disease. To resolve phylogenetic relationships among isolates, we sequenced 68 is
Externí odkaz:
https://doaj.org/article/bcf9e38f38cf4faab1a4f3ff76c805e9
Autor:
Rutger A. Vos, Albert J. Vilella, Tobias Thierer, Arlin Stoltzfus, Jason E. Stajich, Wei-Gang Qiu, Art F.Y. Poon, Sergei L. Kosakovsky Pond, William H. Piel, Brian I. Osborne, Aaron J. Mackey, Paul O. Lewis, Toshiaki Katayama, Alisha Holloway, Richard Holland, Mark Holder, Naohisa Goto, Amy Bouck, James P. Balhoff, Hilmar Lapp, Sendu Bala, Christian M. Zmasek, Derrick J. Zwickl, Todd J. Vision
Publikováno v:
Evolutionary Bioinformatics, Vol 3, Pp 287-296 (2007)
In December, 2006, a group of 26 software developers from some of the most widely used life science programming toolkits and phylogenetic software projects converged on Durham, North Carolina, for a Phyloinformatics Hackathon, an intense five-day col
Externí odkaz:
https://doaj.org/article/d0d2017341124c68b9a42ae007f1bba6
Autor:
Che L. Martin, Tika Y. Sukarna, Saymon Akther, Girish Ramrattan, Pedro Pagan, Lia Di, Emmanuel F. Mongodin, Claire M. Fraser, Steven E. Schutzer, Benjamin J. Luft, Sherwood R. Casjens, Wei-Gang Qiu
Publikováno v:
mBio, Vol 6, Iss 4 (2015)
Externí odkaz:
https://doaj.org/article/f9d09afa000a45e7bb3659d77f825792
Autor:
Che I. Martin, Tika Y. Sukarna, Saymon Akther, Girish Ramrattan, Pedro Pagan, Lia Di, Emmanuel F. Mongodin, Claire M. Fraser, Steven E. Schutzer, Benjamin J. Luft, Sherwood R. Casjens, Wei-Gang Qiu
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT Phylogenomic footprinting is an approach for ab initio identification of genome-wide regulatory elements in bacterial species based on sequence conservation. The statistical power of the phylogenomic approach depends on the degree of sequenc
Externí odkaz:
https://doaj.org/article/3c0992910e414960a014d8bd104cad13
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135655 (2015)
Both bacterial symbionts and pathogens rely on their host-sensing mechanisms to activate the biosynthetic pathways necessary for their invasion into host cells. The Gram-negative bacterium Sinorhizobium meliloti relies on its RSI (ExoR-ExoS-ChvI) Inv
Externí odkaz:
https://doaj.org/article/791fc2708db44064b2631d3fd5cd103b
Genome stability of Lyme disease spirochetes: comparative genomics of Borrelia burgdorferi plasmids.
Autor:
Sherwood R Casjens, Emmanuel F Mongodin, Wei-Gang Qiu, Benjamin J Luft, Steven E Schutzer, Eddie B Gilcrease, Wai Mun Huang, Marija Vujadinovic, John K Aron, Levy C Vargas, Sam Freeman, Diana Radune, Janice F Weidman, George I Dimitrov, Hoda M Khouri, Julia E Sosa, Rebecca A Halpin, John J Dunn, Claire M Fraser
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33280 (2012)
Lyme disease is the most common tick-borne human illness in North America. In order to understand the molecular pathogenesis, natural diversity, population structure and epizootic spread of the North American Lyme agent, Borrelia burgdorferi sensu st
Externí odkaz:
https://doaj.org/article/3c59c5552f0541c5970eb094a0a12062
Autor:
E Oluwabunmi Olapade-Olaopa, Olorunseun O. Ogunwobi, Wei-Gang Qiu, Gargi Pal, Akintunde T. Orunmuyi, Lia Di
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 10, Iss 7, Pp 2257-2264 (2020)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Genetic variation in susceptibility to complex diseases, such as cancer, is well-established. Enrichment of disease associated alleles in specific populations could have implications for disease incidence and prevalence. Prostate cancer (PCa) is a di