Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wei-Chung Chiang"'
Autor:
Zhenyi An, Wei-Chung Chiang, Álvaro F. Fernández, Luis H. Franco, CongCong He, Shu-Yi Huang, Eunmyong Lee, Yang Liu, Salwa Sebti, Sanae Shoji-Kawata, Shyam Sirasanagandla, Richard C. Wang, Yongjie Wei, Yuting Zhao, Silvia Vega-Rubin-de-Celis
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
With great sadness, the scientific community received the news of the loss of Beth Levine on 15 June 2020. Dr. Levine was a pioneer in the autophagy field and work in her lab led not only to a better understanding of the molecular mechanisms regulati
Externí odkaz:
https://doaj.org/article/2060115b1cc8482bb2b9de96a0294242
Autor:
Wei-Chung Chiang, Daniel X Tishkoff, Bo Yang, Joshua Wilson-Grady, Xiaokun Yu, Travis Mazer, Mark Eckersdorff, Steven P Gygi, David B Lombard, Ao-Lin Hsu
Publikováno v:
PLoS Genetics, Vol 8, Iss 9, p e1002948 (2012)
FoxO transcription factors and sirtuin family deacetylases regulate diverse biological processes, including stress responses and longevity. Here we show that the Caenorhabditis elegans sirtuin SIR-2.4--homolog of mammalian SIRT6 and SIRT7 proteins--p
Externí odkaz:
https://doaj.org/article/bb004d8048fb42b5bcb34cc75542201d
Autor:
Wei-chung Chiang, 姜為中
91
Many kinds of microorganisms are capable of regulating genes by Quorum sensing (QS) mechanism. When the cell density reaches at a certain level high, the quorum sensing regulated genes will be activated. In fact, quorum sensing genes are trig
Many kinds of microorganisms are capable of regulating genes by Quorum sensing (QS) mechanism. When the cell density reaches at a certain level high, the quorum sensing regulated genes will be activated. In fact, quorum sensing genes are trig
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/91891674175611937800
Autor:
Xiaonan Dong, Qiren Liang, Yun-Zu Pan, Xiaoyu Wang, Yi-Chun Kuo, Wei-Chung Chiang, Xuewu Zhang, Noelle S. Williams, Josep Rizo, Beth Levine, Jef K. De Brabander
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1510-1516
Autophagy plays essential roles in a wide variety of physiological processes, such as cellular homeostasis, metabolism, development, differentiation, and immunity. Selective pharmacological modulation of autophagy is considered a valuable potential t
Autor:
Jing Guo, Wei-Chung Chiang
Publikováno v:
IUBMB Life. 74:296-316
The clearance of damaged or unwanted mitochondria by autophagy (also known as mitophagy) is a mitochondrial quality control mechanism postulated to play an essential role in cellular homeostasis, metabolism, and development and confers protection aga
Autor:
Yongjie Wei, José Carlos Rodríguez Pérez, Jenna B. Yehl, Matthew J. Ranaghan, Beth Levine, Zhongju Zou, Bruce A. Posner, Yi Chun Kuo, Adam Skepner, Shuguang Wei, Joshua A. Bittker, Wei Chung Chiang, Anwu Zhou
Publikováno v:
ACS Chemical Biology. 13:2247-2260
Autophagy, a lysosomal degradation pathway, plays a crucial role in cellular homeostasis, development, immunity, tumor suppression, metabolism, prevention of neurodegeneration, and lifespan extension. Thus, pharmacological stimulation of autophagy ma
Autor:
Denise K. Marciano, Salwa Sebti, Kathryn L. McMillan, Beth Levine, Orson W. Moe, Tabitha Ting, Gabriele G. Schiattarella, Wei Chung Chiang, Ming Chang Hu, Govind Bhagat, Zhongju Zou, Mingjun Shi, Yang Liu, Congcong He, Álvaro F. Fernández, Yongjie Wei
Publikováno v:
Nature
Autophagy increases the lifespan of model organisms; however, its role in promoting mammalian longevity is less well-established1,2. Here we report lifespan and healthspan extension in a mouse model with increased basal autophagy. To determine the ef
Publikováno v:
Cell. 148(1-2):322-334
SummaryExtended longevity is often correlated with increased resistance against various stressors. Insulin/IGF-1-like signaling (IIS) is known to have a conserved role in aging and cellular mechanisms against stress. In C. elegans, genetic studies su
Publikováno v:
Aging Cell. 10:506-519
One goal of aging research is to develop interventions that combat age-related illnesses and slow aging. Although numerous mutations have been shown to achieve this in various model organisms, only a handful of chemicals have been identified to slow
Autor:
Denise K. Marciano, Ming Chang Hu, Yongjie Wei, Govind Bhagat, Mingjun Shi, Wei Chung Chiang, Tabitha Ting, Gabriele G. Schiattarella, Zhongju Zou, Congcong He, Salwa Sebti, Álvaro F. Fernández, Beth Levine, Yang Liu, Orson W. Moe, Kathryn L. McMillan
Publikováno v:
Nature. 561:E30-E30
In this Letter, the graphs in Fig. 2a and c were inadvertently the same owing to a copy and paste error from the original graphs in Prism. The Source Data files containing the raw data were correct. Fig. 2c has been corrected online.