Zobrazeno 1 - 10
of 140
pro vyhledávání: '"Wei-Chun Chou"'
Publikováno v:
Environmental Health, Vol 21, Iss 1, Pp 1-15 (2022)
Abstract Phthalates are a group of industrial chemicals widely used in everyday products including cosmetics, food packaging and containers, plastics, and building materials. Previous studies have indicated that urinary phthalate metabolites are asso
Externí odkaz:
https://doaj.org/article/da133b0c78fa4f3f9d61ad3d6a0505ee
Autor:
Wei-Chun Chou, Yi-Hsien Cheng, Jim E. Riviere, Nancy A. Monteiro-Riviere, Wolfgang G. Kreyling, Zhoumeng Lin
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Physiologically based pharmacokinetic (PBPK) modeling is an important tool in predicting target organ dosimetry and risk assessment of nanoparticles (NPs). The methodology of building a multi-route PBPK model for NPs has not been
Externí odkaz:
https://doaj.org/article/aa10cf438b8d48268b72ca7a3f8e47b2
Autor:
Po-Chin Huang, Wei-Chun Chou
Publikováno v:
Toxics, Vol 11, Iss 6, p 527 (2023)
Over the last several decades, plasticizers have seamlessly integrated themselves into our daily routines, permeating a vast array of commonly encountered products such as food containers, toys, medicines, building materials, electronic devices, cosm
Externí odkaz:
https://doaj.org/article/02f4e18e2c92450caf47042cf86545f0
Autor:
Qianqian Su, Nengzhou Chen, Jianping Tang, Junxiang Wang, Wei-Chun Chou, Fuli Zheng, Wenya Shao, Guangxia Yu, Ping Cai, Zhenkun Guo, Minghua He, Huangyuan Li, Siying Wu
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 237, Iss , Pp 113503- (2022)
Paraquat (PQ) is a ubiquitously applied herbicide. Long-term PQ exposure with low dose has been reported to induce abnormal expression of long non-coding RNAs (lncRNAs) in brain nerve cells, which could further lead to Parkinson's disease (PD). N6-me
Externí odkaz:
https://doaj.org/article/13d2bb88b05346699b3c0ef11bd89753
Publikováno v:
Environment International, Vol 154, Iss , Pp 106657- (2021)
Phthalates, which are commonly used in flexible plastics and consumer products, have been reported to be toxic to reproductive and developmental function in mammals. Past studies have focused on the toxic effects on male reproduction, with only a few
Externí odkaz:
https://doaj.org/article/d4fc0f878b7f4e3eb3340b779d12251a
Autor:
Wei-Chun Chou, Zhoumeng Lin
Publikováno v:
Environment International, Vol 129, Iss , Pp 408-422 (2019)
A challenge in the risk assessment of perfluorooctane sulfonate (PFOS) is the large interspecies differences in its toxicokinetics that results in substantial uncertainty in the dosimetry and toxicity extrapolation from animals to humans. To address
Externí odkaz:
https://doaj.org/article/12ee7ac79d6b49118ca9b92b993c2a44
Autor:
Wei-Chun Chou, Zhoumeng Lin
Publikováno v:
Environment International, Vol 137, Iss , Pp - (2020)
Background: Environmental exposure to perfluorooctane sulfonate (PFOS) is associated with various adverse outcomes in humans. However, risk assessment for PFOS with the traditional risk estimation method is faced with multiple challenges because ther
Externí odkaz:
https://doaj.org/article/182add6496a14f4d968e50be6adf7ba5
Autor:
Chung-Wei Yang, Chien-Lin Chen, Wei-Chun Chou, Ho-Chen Lin, Yuh-Jyh Jong, Li-Kai Tsai, Chun-Yu Chuang
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157426 (2016)
Spinal muscular atrophy (SMA) is an inherited neuromuscular disease resulting from a recessive mutation in the SMN1 gene. This disease affects multiple organ systems with varying degrees of severity. Exploration of the molecular pathological changes
Externí odkaz:
https://doaj.org/article/538f659ff122450aa9afceef6a46a237
Autor:
Wei-Chun Chou, Yu-The Chung, Hsiao-Yen Chen, Chien-Jen Wang, Tsung-Ho Ying, Chun-Yu Chuang, Ying-Chih Tseng, Shu-Li Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86398 (2014)
Inorganic arsenic (iAs) is an established transplacental agent known to affect fetal development in animal studies. However, iAs has not been adequately studied in the general population with respect to iAs exposure during pregnancy and its impact on
Externí odkaz:
https://doaj.org/article/c6e4801a51b34b53976c3d38f5642cbe
Autor:
Chung-Wei Yang, Wei-Chun Chou, Kuan-Hsueh Chen, An-Lin Cheng, I-Fang Mao, How-Ran Chao, Chun-Yu Chuang
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100576 (2014)
Bisphenol A (BPA) is a ubiquitous endocrine disrupting chemical in our daily life, and its health effect in response to prenatal exposure is still controversial. Early-life BPA exposure may impact brain development and contribute to childhood neurolo
Externí odkaz:
https://doaj.org/article/311ac940b28b41f1988fbe6d32f20635