Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Wei-Chiao Huang"'
Autor:
Annemart Koornneef, Kanika Vanshylla, Gijs Hardenberg, Lucy Rutten, Nika M. Strokappe, Jeroen Tolboom, Jessica Vreugdenhil, Karin Feddes-de Boer, Aditya Perkasa, Sven Blokland, Judith A. Burger, Wei-Chiao Huang, Jonathan F. Lovell, Danielle van Manen, Rogier W. Sanders, Roland C. Zahn, Hanneke Schuitemaker, Johannes P. M. Langedijk, Frank Wegmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract One of the strategies towards an effective HIV-1 vaccine is to elicit broadly neutralizing antibody responses that target the high HIV-1 Env diversity. Here, we present an HIV-1 vaccine candidate that consists of cobalt porphyrin-phospholipi
Externí odkaz:
https://doaj.org/article/b47f9ae471c641c184638edf81cb1133
Publikováno v:
mSphere, Vol 9, Iss 7 (2024)
ABSTRACT Epitopes from the Candida cell surface proteins Fba and Met6 are putative vaccine targets for invasive candidiasis. Here, we describe a Candida vaccine approach in which short peptides derived from Fba and Met6 are used in spontaneous nanoli
Externí odkaz:
https://doaj.org/article/c3899d1ee21f4675b5279d11a863fc12
Autor:
Shiqi Zhou, Karl O.A. Yu, Moustafa T. Mabrouk, Dushyant Jahagirdar, Wei-Chiao Huang, Julio A. Guerra, Xuedan He, Joaquin Ortega, Steven T. Poole, Eric R. Hall, Oscar G. Gomez-Duarte, Milton Maciel, Jr., Jonathan F. Lovell
Publikováno v:
Biomedical Journal, Vol 46, Iss 6, Pp 100588- (2023)
Background: Enterotoxigenic Escherichia coli (ETEC) strains cause infectious diarrhea and colonize host intestine epithelia via surface-expressed colonization factors. Colonization factor antigen I (CFA/I), a prevalent ETEC colonization factor, is a
Externí odkaz:
https://doaj.org/article/ff69563edaf3491ea5971bdac0a3cd29
Autor:
Jonathan F. Lovell, Yeong Ok Baik, Seuk Keun Choi, Chankyu Lee, Jeong-Yoon Lee, Kazutoyo Miura, Wei-Chiao Huang, Young-Shin Park, Sun-Je Woo, Sang Hwan Seo, Jae-Ouk Kim, Manki Song, Chung-Jong Kim, Jae-Ki Choi, Jieun Kim, Eun Ju Choo, Jung-Hyun Choi
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Numerous vaccine strategies are being advanced to control SARS-CoV-2, the cause of the COVID-19 pandemic. EuCorVac-19 (ECV19) is a recombinant protein nanoparticle vaccine that displays the SARS-CoV-2 receptor-binding domain (RBD)
Externí odkaz:
https://doaj.org/article/751995d68b8d49d3808a9e447b241469
Autor:
Wei-Chiao Huang, Moustafa T. Mabrouk, Luwen Zhou, Minami Baba, Mayumi Tachibana, Motomi Torii, Eizo Takashima, Emily Locke, Jordan Plieskatt, C. Richter King, Camila H. Coelho, Patrick E. Duffy, Carole Long, Takafumi Tsuboi, Kazutoyo Miura, Yimin Wu, Tomoko Ishino, Jonathan F. Lovell
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Co-display of two P. falciparum malaria vaccine antigens (Pfs230D1+ and CSP) on the surface of immunogenic liposomes results in functional immune responses upon immunization of mice and rabbits. Combining both antigens produces immune responses that
Externí odkaz:
https://doaj.org/article/f8e6b970eebc47eab359d0eb8d1b356e
Autor:
Kazutoyo Miura, Eizo Takashima, Thao P. Pham, Bingbing Deng, Luwen Zhou, Wei-Chiao Huang, Ababacar Diouf, Yonas T. Gebremicale, Mayumi Tachibana, Tomoko Ishino, C. Richter King, Jonathan F. Lovell, Carole A. Long, Takafumi Tsuboi
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract Pfs230 is a leading malaria transmission blocking vaccine (TBV) candidate. Comprising 3135 amino acids (aa), the large size of Pfs230 necessitates the use of sub-fragments as vaccine immunogens. Therefore, determination of which regions indu
Externí odkaz:
https://doaj.org/article/443d66dfac1e4aaf99ee198dffee8caa
Publikováno v:
APL Bioengineering, Vol 6, Iss 3, Pp 036105-036105-10 (2022)
Pancreatic cancer (PaCa) suffers from poor treatment options for locally advanced cases. Chemophototherapy (CPT) is an emerging anti-tumor modality, and porphyrin–phospholipid liposomes have been shown to be versatile drug carriers for CPT in precl
Externí odkaz:
https://doaj.org/article/3b67ba2b91b1433fbe28dfc64f6e5be5
Publikováno v:
Frontiers in Environmental Science, Vol 10 (2022)
Evaluating the impact of environmental pollution charge system reform is necessary to help formulate a suitable policy to achieve a goal of emission control. The paper examines the relationship between policy adjustment of SO2 emissions charge standa
Externí odkaz:
https://doaj.org/article/11c5d5d39cc343b0b8ff55baf001387d
Autor:
Wei-Chiao Huang, Bingbing Deng, Moustafa T. Mabrouk, Amal Seffouh, Joaquin Ortega, Carole Long, Kazutoyo Miura, Yimin Wu, Jonathan F. Lovell
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-12 (2020)
Abstract Background The Plasmodium falciparum sexual-stage surface proteins Pfs25 and Pfs230 are antigen candidates for a malaria transmission-blocking vaccine (TBV), and have been widely investigated as such. It is not clear whether simultaneously p
Externí odkaz:
https://doaj.org/article/53505351d4854109a223735264100c34
Autor:
Xuedan He, Shiqi Zhou, Breandan Quinn, Wei‐Chiao Huang, Dushyant Jahagirdar, Michael Vega, Joaquin Ortega, Mark D. Long, Fumito Ito, Scott I. Abrams, Jonathan F. Lovell
Publikováno v:
Advanced Science, Vol 8, Iss 24, Pp n/a-n/a (2021)
Abstract Short peptides reflecting major histocompatibility complex (MHC) class I (MHC‐I) epitopes frequently lack sufficient immunogenicity to induce robust antigen (Ag)‐specific CD8+ T cell responses. In the current work, it is demonstrated tha
Externí odkaz:
https://doaj.org/article/e7289c7a9a7a49198481cde87f2c3b75