Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Wei Zhong Zhu"'
Publikováno v:
Proteome Science, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background Sex and age have substantial influence on thyroid function. Sex influences the risk and clinical expression of thyroid disorders (TDs), with age a proposed trigger for the development of TDs. Cardiac function is affected by thyroi
Externí odkaz:
https://doaj.org/article/d911726f14f54308870e4253228729b1
Autor:
Wei Zhong Zhu, Teresa Palazzo, Mowei Zhou, Dolena Ledee, Heather M Olson, Ljiljana Paša-Tolić, Aaron K Olson
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0276285 (2022)
Protein posttranslational modifications (PTMs) by O-GlcNAc globally rise during pressure-overload hypertrophy (POH). However, a major knowledge gap exists on the specific proteins undergoing changes in O-GlcNAc levels during POH primarily because thi
Externí odkaz:
https://doaj.org/article/f998fde05451410db0a46077e4aab522
Publikováno v:
Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Abstract Protein posttranslational modifications (PTMs) by O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) rise during pressure‐overload hypertrophy (POH) to affect hypertrophic growth. The hexosamine biosynthesis pathway (HBP) branches from gly
Externí odkaz:
https://doaj.org/article/7d5a8ff38b284bb7ac320dabff805568
Autor:
Dominic Filice, Wahiba Dhahri, Joell L. Solan, Paul D. Lampe, Erin Steele, Nikita Milani, Benjamin Van Biber, Wei-Zhong Zhu, Tamilla Sadikov Valdman, Rocco Romagnolo, José David Otero-Cruz, Kip D. Hauch, Matthew W. Kay, Narine Sarvazyan, Michael A. Laflamme
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-18 (2020)
Abstract Background Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) show tremendous promise for cardiac regeneration, but the successful development of hESC-CM-based therapies requires improved tools to investigate their electrical behavi
Externí odkaz:
https://doaj.org/article/7f1f8dac3ed3440dba9a6860419e0e8d
Publikováno v:
The Journal of Biological Chemistry
The hexosamine biosynthesis pathway (HBP) branches from glycolysis and forms UDP-GlcNAc, the moiety for O-linked β-GlcNAc (O-GlcNAc) post-translational modifications. An inability to directly measure HBP flux has hindered our understanding of the fa
Autor:
Wei Zhong Zhu, Teresa Palazzo, Mowei Zhou, Dolena Ledee, Heather M Olson, Ljiljana Paša-Tolić, Aaron K. Olson
Protein posttranslational modifications (PTMs) by O-GlcNAc globally rise during pressure-overload hypertrophy (POH). However, only a few specific proteins with altered O-GlcNAc levels during POH are known primarily because this PTM is easily lost dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b43a5b9d42bf80b4739787d0769b420
https://doi.org/10.1101/2022.02.17.480962
https://doi.org/10.1101/2022.02.17.480962
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Protein posttranslational modifications (PTMs) by O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) rise during pressure‐overload hypertrophy (POH) to affect hypertrophic growth. The hexosamine biosynthesis pathway (HBP) branches from glycolysis t
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5407 (2009)
We investigated the mechanisms of excitation-contraction (EC) coupling in human embryonic stem cell-derived cardiomyocytes (hESC-CMs) and fetal ventricular myocytes (hFVMs) using patch-clamp electrophysiology and confocal microscopy. We tested the hy
Externí odkaz:
https://doaj.org/article/f5195646e0304fa5926a5066fd85914d
Autor:
Shi-Han Chen, Wei-Jun Cen, Norman E. Buroker, Xiu-Feng Wu, Kui Li, Xue-Han Ning, Zhao-Nian Zhou, C. Ronald Scott, Wei-Zhong Zhu
Publikováno v:
Hypoxia
Norman E Buroker,1 Xue-Han Ning,1,2,† Zhao-Nian Zhou,3 Kui Li,4 Wei-Jun Cen,4 Xiu-Feng Wu,3 Wei-Zhong Zhu,5 C Ronald Scott,1 Shi-Han Chen1 1Department of Pediatrics, University of Washington, 2Division of Cardiology, Seattle Children’s Hospital R
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Protein posttranslational modifications by O ‐linked β‐N‐acetylglucosamine (O‐GlcNAc) increase with cardiac hypertrophy, yet the functional effects of these changes are incompletely understood. In other organs, O‐GlcNAc promotes