Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts.

Autor: Widjaja AA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Viswanathan S; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Jinrui D; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Singh BK; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Tan J; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore., Wei Ting JG; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Lamb D; Boehringer Ingelheim, Immunology and Respiratory, Ingelheim am Rhein, Germany., Shekeran SG; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., George BL; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Schafer S; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Carling D; MRC-London Institute of Medical Sciences, London, United Kingdom., Adami E; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore., Cook SA; Cardiovascular and Metabolic Disorders Program, Duke-National University of Singapore Medical School, Singapore, Singapore.; National Heart Research Institute Singapore, National Heart Centre Singapore, Singapore, Singapore.; MRC-London Institute of Medical Sciences, London, United Kingdom.

Publikováno v: Frontiers in molecular biosciences [Front Mol Biosci] 2021 Sep 28; Vol. 8, pp. 740650. Date of Electronic Publication: 2021 Sep 28 (Print Publication: 2021).

IL11-mediated stromal cell activation may not be the master regulator of pro-fibrotic signaling downstream of TGFβ.

Autor: Yunhao Tan, Mosallanejad, Kenta, Qingxiu Zhang, O'Brien, Stephen, Clements, Meghan, Perper, Stuart, Wilson, Sarah, Chaulagain, Sudiksha, Jing Wang, Abdalla, Mary, Al-Saidi, Helen, Butt, Danyal, Clabbers, Anca, Ofori, Kwasi, Dillon, Beth, Harvey, Bohdan, Memmott, John, Negron, Christopher, Winarta, David, Tan, Catherine

Publikováno v: Frontiers in Immunology; 2024, p01-15, 15p

LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.

Autor: Proteau, Sarah, Krossa, Imène, Husser, Chrystel, Guéguinou, Maxime, Sella, Federica, Bille, Karine, Irondelle, Marie, Dalmasso, Mélanie, Barouillet, Thibault, Cheli, Yann, Pisibon, Céline, Arrighi, Nicole, Nahon‐Estève, Sacha, Martel, Arnaud, Gastaud, Lauris, Lassalle, Sandra, Mignen, Olivier, Brest, Patrick, Mazure, Nathalie M, Bost, Frédéric

Publikováno v: EMBO Molecular Medicine; 12/7/2023, Vol. 15 Issue 12, p1-18, 18p

SARS-CoV-2 accessory proteins involvement in inflammatory and profibrotic processes through IL11 signaling.

Autor: López-Ayllón, Blanca D., de Lucas-Rius, Ana, Mendoza-García, Laura, García-García, Tránsito, Fernández-Rodríguez, Raúl, Suárez-Cárdenas, José M., Milhano Santos, Fátima, Corrales, Fernando, Redondo, Natalia, Pedrucci, Federica, Zaldívar-López, Sara, Jiménez-Marín, Ángeles, Garrido, Juan J., Montoya, María

Publikováno v: Frontiers in Immunology; 2023, p1-15, 15p

The Pathobiology of Interleukin 11 in Mammalian Disease is Likely Explained by its Essential Evolutionary Role for Fin Regeneration.

Autor: Cook, Stuart A.

Publikováno v: Journal of Cardiovascular Translational Research; Aug2023, Vol. 16 Issue 4, p755-757, 3p