Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Wei Ren Tan"'
The LIDPAD Mouse Model Captures the Multisystem Interactions and Extrahepatic Complications in MASLD
Autor:
Zun Siong Low, Damien Chua, Hong Sheng Cheng, Rachel Tee, Wei Ren Tan, Christopher Ball, Norliza Binte Esmail Sahib, Ser Sue Ng, Jing Qu, Yingzi Liu, Haiyu Hong, Chaonong Cai, Nandini Chilagondanahalli Lakshmi Rao, Aileen Wee, Mark Dhinesh Muthiah, Zoë Bichler, Barbara Mickelson, Mei Suen Kong, Vanessa Shiyun Tay, Zhuang Yan, Jiapeng Chen, Aik Seng Ng, Yun Sheng Yip, Marcus Ivan Gerard Vos, Nicole Ashley Tan, Dao Liang Lim, Debbie Xiu En Lim, Manesh Chittezhath, Jadegoud Yaligar, Sanjay Kumar Verma, Harish Poptani, Xue Li Guan, Sambasivam Sendhil Velan, Yusuf Ali, Liang Li, Nguan Soon Tan, Walter Wahli
Publikováno v:
Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) represents an impending global health challenge. Current management strategies often face setbacks, emphasizing the need for preclinical models that faithfully mimic the huma
Externí odkaz:
https://doaj.org/article/516eada6ebe94695a2023966be28ab43
Autor:
Shern Ping Choy, Byung Jin Kim, Alexandra Paolino, Wei Ren Tan, Sarah Man Lin Lim, Jessica Seo, Sze Ping Tan, Luc Francis, Teresa Tsakok, Michael Simpson, Jonathan N. W. N. Barker, Magnus D. Lynch, Mark S. Corbett, Catherine H. Smith, Satveer K. Mahil
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Skin diseases affect one-third of the global population, posing a major healthcare burden. Deep learning may optimise healthcare workflows through processing skin images via neural networks to make predictions. A focus of deep learning resea
Externí odkaz:
https://doaj.org/article/7895d670344740b89be10ad97311a1b5
Autor:
Jeannie Xue Ting Lee, Wei Ren Tan, Zun Siong Low, Jia Qi Lee, Damien Chua, Wisely Duan Chi Yeo, Benedict See, Marcus Ivan Gerard Vos, Tomohiko Yasuda, Sachiyo Nomura, Hong Sheng Cheng, Nguan Soon Tan
Publikováno v:
Advanced Science, Vol 10, Iss 31, Pp n/a-n/a (2023)
Abstract Metastasis involves epithelial‐to‐mesenchymal transition (EMT), a process that is regulated by complex gene networks, where their deliberate disruption may yield a promising outcome. However, little is known about mechanisms that coordin
Externí odkaz:
https://doaj.org/article/a5859c74baa34b13a85c57472ea4df78
Autor:
Yee Kit Tai, Karen Ka Wing Chan, Charlene Hui Hua Fong, Sharanya Ramanan, Jasmine Lye Yee Yap, Jocelyn Naixin Yin, Yun Sheng Yip, Wei Ren Tan, Angele Pei Fern Koh, Nguan Soon Tan, Ching Wan Chan, Ruby Yun Ju Huang, Jing Ze Li, Jürg Fröhlich, Alfredo Franco-Obregón
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/cb405a7498e74f0e998e803dbd50251f
Autor:
Yee Kit Tai, Karen Ka Wing Chan, Charlene Hui Hua Fong, Sharanya Ramanan, Jasmine Lye Yee Yap, Jocelyn Naixin Yin, Yun Sheng Yip, Wei Ren Tan, Angele Pei Fern Koh, Nguan Soon Tan, Ching Wan Chan, Ruby Yun Ju Huang, Jing Ze Li, Jürg Fröhlich, Alfredo Franco-Obregón
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Chemotherapy is the mainstream treatment modality for invasive breast cancer. Unfortunately, chemotherapy-associated adverse events can result in early termination of treatment. Paradoxical effects of chemotherapy are also sometimes observed, whereby
Externí odkaz:
https://doaj.org/article/8966f7af1cf7441cad9994a85e837885
Autor:
Maegan Miang Kee Lim, Jonathan Wei Kiat Wee, Jen Chi Soong, Damien Chua, Wei Ren Tan, Marco Lizwan, Yinliang Li, Ziqiang Teo, Wilson Wen Bin Goh, Pengcheng Zhu, Nguan Soon Tan
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Overcoming multidrug resistance has always been a major challenge in cancer treatment. Recent evidence suggested epithelial-mesenchymal transition plays a role in MDR, but the mechanism behind this link remains unclear. We found that the exp
Externí odkaz:
https://doaj.org/article/31574e4da91348bdb307ddd59eba8376
Autor:
Wendy Wen Ting Phua, Wei Ren Tan, Yun Sheng Yip, Ivan Dongzheng Hew, Jonathan Wei Kiat Wee, Hong Sheng Cheng, Melvin Khee Shing Leow, Walter Wahli, Nguan Soon Tan
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1747 (2020)
Daily activities expose muscles to innumerable impacts, causing accumulated tissue damage and inflammation that impairs muscle recovery and function, yet the mechanism modulating the inflammatory response in muscles remains unclear. Our study suggest
Externí odkaz:
https://doaj.org/article/9a09a68a869447a3b4dd0470c4cb219e
Exploration and Development of PPAR Modulators in Health and Disease: An Update of Clinical Evidence
Autor:
Hong Sheng Cheng, Wei Ren Tan, Zun Siong Low, Charlie Marvalim, Justin Yin Hao Lee, Nguan Soon Tan
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 20, p 5055 (2019)
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that govern the expression of genes responsible for energy metabolism, cellular development, and differentiation. Their crucial biological roles dictate the significance of PPA
Externí odkaz:
https://doaj.org/article/d4da5c09add84b2b86c9b1679af68387
Autor:
Yong Yao Chun, William Wei Ren Tan, Marcus Ivan Gerard Vos, Wen Kiat Chan, Hong Liang Tey, Nguan Soon Tan, Timothy Thatt Yang Tan
Publikováno v:
Biomaterials Science. 10:3963-3971
Currently, there is no effective method to prevent the formation of hypertrophic scars and keloids, which can cause severe physical and psychological burdens to patients. Secreted protein acidic and cysteine-rich (SPARC) is involved in wound fibrosis
Autor:
Zun Siong Low, Damien Chua, Hong Sheng Cheng, Rachel Tee, Wei Ren Tan, Christopher Ball, Norliza Binte Esmail Sahib, Ser Sue Ng, Jing Qu, Yingzi Liu, Haiyu Hong, Chaonong Cai, Nandini C. L. Rao, Aileen Wee, Mark D. Muthiah, Zoë Bichler, Barbara Mickelson, Jia Qi Lee, Mei Suen Kong, Vanessa S.Y. Tay, Zhuang Yan, Jiapeng Chen, Aik Seng Ng, Yun Sheng Yip, Marcus Ivan Gerard Vos, Debbie Xiu En Lim, Manesh Chittezhath, Jadegoud Yaligar, Sanjay Kumar Verma, Harish Poptani, Xue Li Guan, S. Sendhil Velan, Yusuf Ali, Liang Li, Nguan Soon Tan, Walter Wahli
Adaptive T-cell immune response is essential in conferring protective immunity, a process requiring tight cellular homeostasis regulation. Pathological intrahepatic T-cell landscape has a role in NAFLD propagation; however, its activation remains unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fa97f1db42b4fa5bd0adf6381fb62d1
https://doi.org/10.1101/2023.01.10.523354
https://doi.org/10.1101/2023.01.10.523354