Zobrazeno 1 - 10
of 31 033
pro vyhledávání: '"Wei Q."'
Autor:
Wei Q. Deng, Marie Pigeyre, Sandi M. Azab, Samantha L. Wilson, Natalie Campbell, Nathan Cawte, Katherine M. Morrison, Stephanie A. Atkinson, Padmaja Subbarao, Stuart E. Turvey, Theo J. Moraes, Piush Mandhane, Meghan B. Azad, Elinor Simons, Guillaume Pare, Sonia S. Anand
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Epigenetic modifications, particularly DNA methylation (DNAm) in cord blood, are an important biological marker of how external exposures during gestation can influence the in-utero environment and subsequent offspring development
Externí odkaz:
https://doaj.org/article/8f65a94602924fa59ab13c529f08c2be
Autor:
Nazia Pathan, Wei Q. Deng, Matteo Di Scipio, Mohammad Khan, Shihong Mao, Robert W. Morton, Ricky Lali, Marie Pigeyre, Michael R. Chong, Guillaume Paré
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract It has been postulated that rare coding variants (RVs; MAF 5%, with height having the highest h 2 RV at 21.9% (95% CI: 19.0-24.8%). The total heritability, including common and rare variants, recovered pedigree-based estimates for 11 traits.
Externí odkaz:
https://doaj.org/article/c178b4267dff4643bed6e59ce258ffbb
Publikováno v:
HortTechnology, Vol 33, Iss 1, Pp 98-102 (2022)
Firmness is an important fruit quality trait in northern highbush blueberry (Vaccinium corymbosum). Many researchers, growers, and packers rely on machines for measuring firmness right after harvest and during postharvest cold storage of fresh fruit.
Externí odkaz:
https://doaj.org/article/16ede8b656004968a1ed73d607de1f5d
Autor:
Lei Cui, Gao F. Wang, Xin Li, Yu Q. Song, Wen W. Pu, De K. Zhang, Wei Q. Jiang, Ya Q. Kou, Zhao Q. Tan, Ran Tao, Yan Han, Yu D. Han
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
ObjectiveConventional second window indocyanine green (SWIG) technique has been widely attempted in near-infrared fluorescence (NIRF) imaging for intraoperative navigation of tumor radical resection. Nevertheless, the overuse of indocyanine green (IC
Externí odkaz:
https://doaj.org/article/9dc1ae3693794b468c51279d0fbdd56b
Autor:
Lei Cui, Wei Q. Jiang, De K. Zhang, Gao F. Wang, Yu D. Han, Wen W. Pu, Yan Shao, Lin L. Guo, Ran Tao, Yan Han
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
BackgroundThe goal of the current study was to explore the application of preoperative three-dimensional reconstruction (3DR) based on thin-slice magnetic resonance imaging (MRI) in the simultaneous guidance of en bloc tumor resection and adjacent pe
Externí odkaz:
https://doaj.org/article/e6eab2423d674e2cba23f743b53acfd3
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
O’Keefe et al. investigate the integration of type III single-pass transmembrane proteins targeted to the ER and examine the roles of the ER membrane complex, Sec61 complex and signal recognition particle receptor. As a result, the authors propose
Externí odkaz:
https://doaj.org/article/5c449021283a45d288dc2d9c2bd63056
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The Sec61 complex translocates nascent polypeptides into and across the membrane of the endoplasmic reticulum (ER), providing access to the secretory pathway. In this study, we show that Ipomoeassin-F (Ipom-F), a selective inhibitor of prote
Externí odkaz:
https://doaj.org/article/84a590a1a842429faa233bc88b29e96b
Autor:
Sarah O’Keefe, Pratiti Bhadra, Kwabena B. Duah, Guanghui Zong, Levise Tenay, Lauren Andrews, Hayden Schneider, Ashley Anderson, Zhijian Hu, Hazim S. Aljewari, Belinda S. Hall, Rachel E. Simmonds, Volkhard Helms, Stephen High, Wei Q. Shi
Publikováno v:
Molecules, Vol 27, Iss 14, p 4419 (2022)
The plant-derived macrocyclic resin glycoside ipomoeassin F (Ipom-F) binds to Sec61α and significantly disrupts multiple aspects of Sec61-mediated protein biogenesis at the endoplasmic reticulum, ultimately leading to cell death. However, extensive
Externí odkaz:
https://doaj.org/article/49403f4f406c4963bef757e4b156aeea
Autor:
Aurélien Macé, Marcus A. Tuke, Patrick Deelen, Kati Kristiansson, Hannele Mattsson, Margit Nõukas, Yadav Sapkota, Ursula Schick, Eleonora Porcu, Sina Rüeger, Aaron F. McDaid, David Porteous, Thomas W. Winkler, Erika Salvi, Nick Shrine, Xueping Liu, Wei Q. Ang, Weihua Zhang, Mary F. Feitosa, Cristina Venturini, Peter J. van der Most, Anders Rosengren, Andrew R. Wood, Robin N. Beaumont, Samuel E. Jones, Katherine S. Ruth, Hanieh Yaghootkar, Jessica Tyrrell, Aki S. Havulinna, Harmen Boers, Reedik Mägi, Jennifer Kriebel, Martina Müller-Nurasyid, Markus Perola, Markku Nieminen, Marja-Liisa Lokki, Mika Kähönen, Jorma S. Viikari, Frank Geller, Jari Lahti, Aarno Palotie, Päivikki Koponen, Annamari Lundqvist, Harri Rissanen, Erwin P. Bottinger, Saima Afaq, Mary K. Wojczynski, Petra Lenzini, Ilja M. Nolte, Thomas Sparsø, Nicole Schupf, Kaare Christensen, Thomas T. Perls, Anne B. Newman, Thomas Werge, Harold Snieder, Timothy D. Spector, John C. Chambers, Seppo Koskinen, Mads Melbye, Olli T. Raitakari, Terho Lehtimäki, Martin D. Tobin, Louise V. Wain, Juha Sinisalo, Annette Peters, Thomas Meitinger, Nicholas G. Martin, Naomi R. Wray, Grant W. Montgomery, Sarah E. Medland, Morris A. Swertz, Erkki Vartiainen, Katja Borodulin, Satu Männistö, Anna Murray, Murielle Bochud, Sébastien Jacquemont, Fernando Rivadeneira, Thomas F. Hansen, Albertine J. Oldehinkel, Massimo Mangino, Michael A. Province, Panos Deloukas, Jaspal S. Kooner, Rachel M. Freathy, Craig Pennell, Bjarke Feenstra, David P. Strachan, Guillaume Lettre, Joel Hirschhorn, Daniele Cusi, Iris M. Heid, Caroline Hayward, Katrin Männik, Jacques S. Beckmann, Ruth J. F. Loos, Dale R. Nyholt, Andres Metspalu, Johan G. Eriksson, Michael N. Weedon, Veikko Salomaa, Lude Franke, Alexandre Reymond, Timothy M. Frayling, Zoltán Kutalik
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Individual SNPs have small effects on anthropometric traits, yet the impact of CNVs has remained largely unknown. Here, Kutalik and co-workers perform a large-scale genome-wide meta-analysis of structural variation and find rare CNVs associated with
Externí odkaz:
https://doaj.org/article/6a8ab1d070da4fdd8e0c0617397195b3