Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Wei Ping Yu"'
Autor:
Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li, Valerie C. L. Lin
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background Progesterone receptor (PGR) is a master regulator of uterine function through antagonistic and synergistic interplays with oestrogen receptors. PGR action is primarily mediated by activation functions AF1 and AF2, but their physio
Externí odkaz:
https://doaj.org/article/0c308420b4a04419b0f697e9c3cba5b0
Autor:
Sarivin Vanan, Xiaoxia Zeng, Sook Yoong Chia, Katarina Varnäs, Mei Jiang, Ke Zhang, Wuan Ting Saw, Parasuraman Padmanabhan, Wei-Ping Yu, Zhi-Dong Zhou, Christer Halldin, Balázs Gulyás, Eng-King Tan, Li Zeng
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-15 (2020)
Abstract Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that mediates the retrograde transport of cargo proteins from endosomes to the trans-Golgi network. Mutations such as D620N in the VPS35 gene have been identifi
Externí odkaz:
https://doaj.org/article/85c535b2d2c24c6982aab9b8d5a79aef
Autor:
Shi Hao Lee, Chew Leng Lim, Wei Shen, Samuel Ming Xuan Tan, Amanda Rui En Woo, Yeannie H. Y. Yap, Caitlyn Ang Su Sian, Wilson Wen Bin Goh, Wei-Ping Yu, Li Li, Valerie C. L. Lin
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/e344ca4e32cf41d6897fa6cc69708ef8
Autor:
Huimei Chen, Aida Moreno-Moral, Francesco Pesce, Nithya Devapragash, Massimiliano Mancini, Ee Ling Heng, Maxime Rotival, Prashant K. Srivastava, Nathan Harmston, Kirill Shkura, Owen J. L. Rackham, Wei-Ping Yu, Xi-Ming Sun, Nicole Gui Zhen Tee, Elisabeth Li Sa Tan, Paul J. R. Barton, Leanne E. Felkin, Enrique Lara-Pezzi, Gianni Angelini, Cristina Beltrami, Michal Pravenec, Sebastian Schafer, Leonardo Bottolo, Norbert Hubner, Costanza Emanueli, Stuart A. Cook, Enrico Petretto
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Pathological cardiac fibrosis is a hallmark of diseases leading to heart failure. Here, the authors used systems genetics to identify a pro-fibrotic gene network regulated by WWP2, a E3 ubiquitin ligase, which orchestrates the nucleocytoplasmic shutt
Externí odkaz:
https://doaj.org/article/cfb1b8ece2684ea692a537c58f79dad3
Autor:
Mei Jiang, Hai-Tao Tu, Ke Zhang, Wei Zhang, Wei-Ping Yu, Jie Xu, Eng-King Tan, Kai-Hua Guo, Li Zeng
Publikováno v:
Neurobiology of Disease, Vol 153, Iss , Pp 105313- (2021)
Vacuolar protein sorting protein 35 (VPS35) is a core component of the retromer complex involved in regulating protein trafficking and retrieval. Recently, a missense mutation, Asp620Asn (D620N), in VPS35 (PARK17) has been identified as a pathogenic
Externí odkaz:
https://doaj.org/article/3b65c2cfcdf94ee58e96f900eb27d2ea
Cobalt ion interaction with TMEM16A calcium-activated chloride channel: Inhibition and potentiation.
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231812 (2020)
TMEM16A, a Ca2+-sensitive Cl- channel, plays key roles in many physiological functions related to Cl- transport across lipid membranes. Activation of this channel is mediated via binding intracellular Ca2+ to the channel with a relatively high appare
Externí odkaz:
https://doaj.org/article/01de2e1c569a40a18a2c0424d3c0767f
Autor:
Jing, Zhai, Sheeja, Navakkode, Sean Qing Zhang, Yeow, Kumar, Krishna-K, Mui Cheng, Liang, Joanne Huifen, Koh, Rui Xiong, Wong, Wei Ping, Yu, Sreedharan, Sajikumar, Hua, Huang, Tuck Wah, Soong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(32)
L-type Ca
Autor:
Zhi-Wei, Zhang, Haitao, Tu, Mei, Jiang, Sarivin, Vanan, Sook Yoong, Chia, Se-Eun, Jang, Wuan-Ting, Saw, Zhi-Wei, Ong, Dong-Rui, Ma, Zhi-Dong, Zhou, Jie, Xu, Kai-Hua, Guo, Wei-Ping, Yu, Shuo-Chien, Ling, Richard A, Margolin, Daniel G, Chain, Li, Zeng, Eng-King, Tan
Publikováno v:
Science signaling. 15(748)
Gain-of-function mutations in the leucine-rich repeat kinase 2 (
Autor:
Jing Zhai, Sheeja Navakkode, Sean Qing Zhang Yeow, Kumar Krishna-K, Mui Cheng Liang, Joanne Huifen Koh, Rui Xiong Wong, Wei Ping Yu, Sreedharan Sajikumar, Hua Huang, Tuck Wah Soong
Publikováno v:
Proceedings of the National Academy of Sciences. 119
L-type Ca V 1.3 calcium channels are expressed on the dendrites and soma of neurons, and there is a paucity of information about its role in hippocampal plasticity. Here, by genetic targeting to ablate Ca V 1.3 RNA editing, we demonstrate that unedit
Autor:
Huimei Chen, Aida Moreno-Moral, Francesco Pesce, Nithya Devapragash, Massimiliano Mancini, Ee Ling Heng, Maxime Rotival, Prashant K. Srivastava, Nathan Harmston, Kirill Shkura, Owen J. L. Rackham, Wei-Ping Yu, Xi-Ming Sun, Nicole Gui Zhen Tee, Elisabeth Li Sa Tan, Paul J. R. Barton, Leanne E. Felkin, Enrique Lara-Pezzi, Gianni Angelini, Cristina Beltrami, Michal Pravenec, Sebastian Schafer, Leonardo Bottolo, Norbert Hubner, Costanza Emanueli, Stuart A. Cook, Enrico Petretto
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/28195d5a2cfd4a2ca91a728a572eb369